The medicine "Bromocriptine", the instructions for use indicate release in the form of tablets of 2.5 mg. The active substance is bromocriptine mesylate.
The drug belongs to the clinical and pharmacological group of inhibitors of prolactin secretion. The pharmacological effect is based on the ability of Bromocriptine to improve the functioning of dopamine receptors and inhibit the synthesis of prolactin in the body. As a result, the process of physiological lactation stops and the menstrual cycle normalizes.
The drug "Bromocriptine", the instruction indicates, ensures the balance of the hormonal level, the balance between progesterone and estrogens. This makes it possible to eliminate cysts formed in the mammary gland, at least to reduce their size. The drug is not associated with a risk of developing thromboembolism or postpartum uterine involution. Tablets are taken to regulate the body's production of luteinizing hormone and reduce the manifestations of polycystic ovary.
Under the influence of the drug, the growth of the pituitary adenoma producing prolactin stops, its size decreases. High doses of bromocriptine are able to restore the neurochemical balance in the organs of the brain, stimulate their work.
The medication "Bromocriptine", the instruction indicates, significantly improves the condition of patients with Parkinson's syndrome. Blocks tremor and stiffness, activates movement at all stages of the development of the diagnosis. Additionally, with the help of the drug, the symptoms of depression that occur during Parkinson's disease are eliminated .
The active substance inhibits the production of pituitary hormones such as somatotropic and adrenocorticotropic, but at the same time does not affect the synthesis of other hormones.
The drug "Bromocriptine." Instruction Indications
The doctor prescribes the drug in the following cases:
- with violations of the menstrual cycle;
- with established diagnoses associated with prolactin dependence;
- with amenorrhea, including complicated galactorrhea;
- with female infertility;
- with oligomenorrhea;
- with failure of the luteal phase;
- with hyperprolactinemia of the secondary type, which developed against the background of prolonged use of certain drugs;
- with female infertility, not associated with prolactin addiction;
- with polycystic ovary;
- with anovulatory cycles ;
- with premenstrual syndrome with tenderness of the mammary glands, swelling, flatulence, mood swings;
- with hyperprolactinemia in men;
- with oligospermia, lack of libido, impotence;
- with pituitary prolactinomas ;
- in preparation for surgery to reduce the volume of the tumor;
- during rehabilitation after operations in those cases when the level of prolactin is elevated ;
- with acromegaly;
- to suppress lactation, including after an abortion;
- with a thickening of the mammary glands after childbirth;
- with mastitis after childbirth;
- with diseases of the mammary glands;
- with mastalgia;
- with benign nodal or cystic changes;
- with Parkinson's disease in complex treatment or as monotherapy.
The dosage of the drug is chosen by the doctor, depending on the diagnosis and condition of the patient.
The drug "Bromocriptine", side effects
Digestive system disorders are manifested by nausea, vomiting, dry mouth, constipation, diarrhea.
Disturbances in the cardiovascular system are manifested by hypotension, arrhythmia; in single patients , Raynaud's syndrome was observed as a result of prolonged use .
Disturbances in the functioning of the nervous system occur at the beginning of the course of treatment, appear dizziness, headache, drowsiness, nervous agitation, dyskinesia, decreased vision, hallucinations.
Allergic reactions were observed only in the form of a skin rash.
Very rarely it was mentioned about nasal congestion, about cramps in the calf muscles.
The drug "Bromocriptine." Instruction Contraindications
You can not prescribe the drug for arterial hypertension, tremor, Gettington's chorea, psychosis, cardiovascular disease, and liver failure. Contraindications include gastrointestinal ulcer.
The drug is not intended for use by children under the age of 15, pregnant women with toxicosis, patients with hypersensitivity to ergot derivatives. For the production of Bromocriptine, ergot is used.