The substance ipratropium bromide belongs to the pharmacological group of anticholinergics. On the basis of this medicinal component, preparations are made under the name Atrovent and Ipovent.
Composition and format of drug release
Ipratropium bromide is the active ingredient in drugs such as Atrovent and Ipovent. Auxiliary components of these drugs are benzalkonium chloride, disodium edetate and hydrochloric acid with purified water. Medicines are available in the form of a solution for inhalation and aerosol.
Also on sale are ipratropium bromide + phenoterol. This tool is a combination drug, which has a pronounced bronchodilator effect, due to the action of the constituent substances.
The combination of ipratropium bromide + fenoterol increases the effectiveness of bronchodilator treatment of pathologies that are accompanied by hypersecretion of mucus and increased tone of bronchial muscles. As a result, the agent can be used in lower doses than with monotherapy.
Indications for the use of a medicinal substance
The substance ipratropium bromide for treatment is prescribed to patients in a number of cases:
- For the treatment and prevention of chronic respiratory diseases. In this case, the drug is used for lung diseases with a decrease in bronchial lumen.
- Against the background of chronic obstructive bronchitis. In this case, the active component helps in the presence of inflammation of the bronchi, which is combined with impaired air patency.
- Also, the use of ipratropium bromide is advisable in patients with mild to moderate bronchial asthma, especially with concomitant pathologies of the cardiac and vascular system.
- Against the background of bronchial spasms during surgical operations.
Mode of application
What does the instruction for ipratropium bromide tell us? The method of use of this medical substance is set individually. This takes into account the age of the patients, and in addition, sensitivity to the drug and the type of disease.
Dosed aerosol for adult patients and children over three years of age, for the prevention of respiratory failure in the presence of chronic obstructive bronchitis and bronchial asthma, two doses are prescribed on average three times a day. In the process of using the drug for medicinal purposes, it is allowed to perform additional inhalations in three doses of aerosol.
The solution for inhalation for adult patients and children over six years of age is prescribed up to five times a day. When using an electric atomizer, as well as using respirators, a single dose will count as eight drops in a spray device. In the framework of using a manual sprayer, up to thirty breaths of undiluted solution are taken. Powder for inhalation in the treatment of adults and children over six years of age is used in an amount of 0.2 milligrams three times a day.
Ipratropium bromide is commonly used as part of monotherapy. But drugs based on this substance can also be used in combination with adrenoreceptor stimulants, and in addition, they are often combined with xanthine derivatives.
Side effects
Against the background of taking the described medicinal substance in humans, one or another adverse reaction can often occur. Usually this is dry mouth, along with an increase in the viscosity of sputum. In case of contact with eyes, as well as in case of accommodation disturbances (that is, against the background of pathology of visual perception), people with closed-angle glaucoma may experience a significant increase in intraocular pressure.
When using an aerosol intranasally (that is, directly in the nose) in some situations, local reactions may occur in the form of dryness in the nose and irritation of its mucosa. In addition, allergic reactions are not excluded.
Contraindications
The presented drug component is contraindicated in patients in a number of cases:
- With increased sensitivity of the body.
- Dosed aerosol intended for intranasal use is not recommended in the instructions for children under six years of age.
- It is very important to be careful when prescribing the drug to patients suffering from angle-closure glaucoma, and in addition, obstruction.
- Against the background of urinary tract diseases due to an increase in the volume of the prostate gland in men.
- At the beginning of pregnancy, the drug presented is used only on the basis of strict indications.
The aerosol can with ipratropium bromide must be stored away from fire, and also away from sources of high temperature.
Analogues of the drug
Analogues of the described drug include medications like Vagos, Itrop, Arutropida and Normosekretol. These medicines should be selected by a doctor.
Pharmacological group
Ipratropium bromide is classified as a medicine used to treat bronchi and lungs. This active component belongs to anti-asthma drugs, as well as to the category of beta-adrenoreceptor stimulants.
Reviews
Drugs based on the presented medical substance are reported to be effective in controlling cough. It is noted that thanks to ipratropium bromide, which is included in drugs such as Atrovent and Ipovent, people manage to achieve a stable therapeutic effect in the presence of diseases of the bronchi and lungs.
In the reviews, people note the convenience of the product in use and emphasize the affordable price, which is about two hundred rubles for drugs based on this ingredient. It is also reported that this tool helps well in the presence of coughing smokers, perfectly irrigating the bronchi and lungs. Consumers also praise this component for helping to fight colds.
Significant disadvantages of people include the presence of side effects that ipratropium bromide provokes. For example, reviews often report dry mouth and increased viscosity of sputum. An additional inconvenience is caused by the fact that this medical substance has many different contraindications for use.
Thus, ipratropium bromide, according to reviews, is an effective component of drugs and helps patients cope with respiratory pathologies. But when using drugs containing this active substance, contraindications and possible adverse reactions should be taken into account.
We reviewed the instructions for use with ipratropium bromide.