In the article, we consider the instructions for use, price, reviews and analogues for the Mebendazole preparation. The medication is an antiparasitic drug of synthetic origin, which has an effect on a wide range of helminths. The drug is most effective against round varieties of worms, but it can also affect tape species.
Description
According to the instructions for use, Mebendazole is used in the treatment of diseases caused by various helminths. The drug is available exclusively in tablet form, packaged in 6 pieces in one package. You can buy it only after receiving a prescription from a doctor.
Instructions for use with Mebendazole Farmland are very detailed.
Structure
The active component of the drug, represented by mebendazole, disrupts the metabolism of glucose in helminths, which causes their death. If a significant number of parasites are detected, experts recommend using Mebendazole in combination with piperazine. Taking these drugs will help to avoid the accumulation of helminths in the bile ducts or appendix.
The effect of the drug is described as prolonged. Its effect is due to the gradual and systematic poisoning of parasites. This is due to the uneven distribution of mebendazole throughout the body, with an emphasis on adipose tissue and liver cells. In the intestines, the drug is poorly absorbed. Residual components with feces, esophagus are excreted, and some part reaches the kidneys and leaves with urine. The maximum amount of active substance in the body accumulates after 4-5 hours after taking the pill. Excretion from the body occurs after two days.
This is confirmed by the instructions for use with Mebendazole.
Application: for children, adults and dogs
In order for the therapy to be as effective as possible, Mebendazole treatment should be passed to all family members living together. The drug is considered the most effective for enterobiasis and trichocephalosis. However, it also shows activity against roundworms, trichinella, echinococcus, hookworm and mixed variants of helminthiasis.
It is not recommended to conduct Mebendazole therapy alone, as this can have unpleasant consequences for the body. Therefore, first of all, you need to undergo an examination and get a specialist appointment.
As indicated by the instructions for use, Mebendazole is administered orally after meals. It is rarely prescribed in the field of pediatrics, as it has a rather large list of possible side effects. However, if other options for the treatment of helminthiasis in a child are not provided, the drug is prescribed in minimum dosages, which are selected based on the weight and type of parasitic infestation.
For adult patients, the drug is prescribed very often. The duration of administration and dosage should be established by a specialist. The dosage also depends on the patient’s body weight and is adjusted depending on its deficiency or an overabundance in a larger or smaller direction.
You can also use, according to the instructions for use, Mebendazole for dogs.
In this case, the drug is always used along with laxatives to avoid the accumulation of parasites in one place and intoxication of the animal's body. The dosage is calculated depending on how badly the body is affected by helminths, as well as on the basis of the animal’s body weight.
Once a year, when summer ends, it is recommended to take a medication in order to prevent helminthiasis. In this case, one tablet per day is sufficient.
How to use "Mebendazole" for children according to the instructions for use?
Children who are under 12 years old are not recommended to take the drug as a preventive measure.
Dosage
According to the instructions for use with Mebendazole, the amount of the drug should be determined taking into account the characteristics of each patient and the type of helminths. During treatment, it is forbidden to drink alcohol and fatty foods. If we are not talking about extensive worming, the use of laxatives in combination with Mebendazole is not considered mandatory.
A single dosage and duration of treatment depend on the diagnosis:
- Echinococcosis. Within three days, five tablets are taken in the morning, at lunch and in the evening. Then a single dosage is determined at the rate of 25-30 mg / 1 kg. The resulting amount of the drug is divided into three doses.
- With gnatostomiasis, ascariasis, teniosis, mixed helminthiasis, strongyloidosis, capillariosis, trichosis and trichocephalosis, the drug is taken one tablet in the morning and evening for at least three days.
- Trichinosis involves taking 2-4 tablets three times a day with a course of three days. Further, the dosage is increased to 5 tablets. In total, treatment should last at least 10 days.
- Enterobiosis. Take one tablet at a time. Repeat after 2-4 weeks.
As for children, their intake of the drug at the age of 2-10 years suggests a dosage of 25-50 mg. mebendazole (a quarter or half tablet) for enterobiasis and a whole tablet per day for other types of helminthiases.
The price of Mebendazole is not indicated in the instructions for use.
Adverse reactions
Adverse reactions during treatment occur quite rarely. Their appearance depends on the individual characteristics of each organism. So, when taking pills, the following symptoms may appear:
- Pain in the head, fatigue, dizziness.
- Dyspepsia, accompanied by abdominal pain in the abdomen and epigastric zone, as well as stool disorders.
- From the skin, hives, hyperthermia, and redness may occur.
- Allergy up to Quincke's edema and convulsive syndrome.
An overdose of the drug can lead to such negative consequences as eosinophilia, neutropenia, leukopenia and other disorders in the blood.
Increased care requires taking "Mebendazole" by those patients who have a history of diabetes. This is due to the property of mebendazole to make adjustments to glucose metabolism. At the age of two years, the drug is prescribed only for health reasons. In most cases at this age, preference is given to more gentle options for the drug.
Contraindications
The drug is contraindicated in the following cases:
- Hypersensitivity to the components of the drug.
- Liver failure.
- Crohn's disease, as well as ulcerative colitis of a non-specific type.
- The period of gestation and breastfeeding.
You should not take the drug at the same time as vitamin E, various fat-soluble drugs and Cimetidine.
This is stated in the instructions for use.
Price of Mebendazole
The cost of the medication is low and averages from 90 to 130 rubles per package. It depends on the region and the pharmacy network. 56-60 hryvnias - the price in Ukraine.
Instructions for use with Mebendazole also do not contain information about analogues. We will consider them below.
Analogs
On the pharmaceutical market there are immediately a number of drugs that have the same composition. The most popular analogues of the drug are:
- "Wormin." The drug is based on mebendazole, produced in tablet form. You can not take "Vormin" for children under three years of age, women during the period of bearing a child and breastfeeding. The main difference between the drug and the original are auxiliary components. It is at this point of the instruction that you should stop your attention when replacing one drug with another.
- "Pirantel." It is an analogue of Mebendazole in terms of its effect on the body. It is produced in various forms, including suspension, capsules and tablets. It is allowed to take children from six months. During pregnancy and lactation, the drug can be taken only for health reasons. This is confirmed by the instructions for use with the analogue of Mebendazole.
- Helminthox. Pyrantel-based drug. It is prescribed to eliminate roundworms and pinworms. It is produced in tablet form and in suspension. The medication can be given to children under six months of age, as well as to pregnant women.
- "Piperazine." Often prescribed in combination with Mebendazole. Children can take pills from the age of three. It is forbidden to take the drug while carrying a child and breastfeeding.
- "Biltricid." There is no experience in treating patients under four years of age, therefore, at this age, the drug is contraindicated.
It is possible to replace Mebendazole with the analogues listed above only after consulting a specialist.
Reviews
Parasitologists speak well of Mebendazole. They highlight the effectiveness of the drug and its effectiveness against many varieties of helminths. Specialists also respond well to the short duration of treatment with the drug. In this case, relapses are usually absent after the first course of treatment. Parasitologists warn against prolonged use of Mebendazole, as this can lead to the development of adverse reactions from the nervous system and digestive organs.
Patients taking the drug also respond well to it. Mebendazole extremely rarely provokes undesirable reactions, while effectively eliminating helminthiases of any origin. The disadvantages of the drug are its relatively high cost, especially when it is necessary to drink 5 tablets three times a day. Such a course of treatment is quite expensive. Causes complaints and a small package of the drug, which is not enough for one course. However, in general, the drug is considered high-quality and effective.
We reviewed the medication "Mebendazole" instructions for use and reviews.