This article provides a complete description of the drug "Neurorubin". The price of the drug will also be indicated in the review. Here you will learn about the composition of the medication, its properties, indications for use, adverse reactions, consumption patterns and more.
Attention! Information on this pharmacological agent is presented for informational purposes only and is not recommended for use in self-medication. The article presents not an official instruction for the use of "Neurorubin", but its simplified version. Before you purchase and start using the medicine, you should consult your doctor. Only a specialist can decide on the purpose of this drug, determining the optimal dosage and method of use for you.
The release form of the drug "Neurorubin"
The drug "Neurorubin" is made in the form of:
1. The tablets are round, convex on both sides, having a pink color, the inscription "TP" and a film shell. Packed in 10 pieces in blisters, which, in turn, are packaged in 2 in cardboard boxes.
2. Injection solution (transparent, red in brown glass ampoules). Each contains 3 ml of the drug and is packaged in an amount of 5 pieces in a cardboard box.
The composition of the drug "Neurorubin"
The drug "Neurorubin" (ampoules) contains: in 3 ml - vitamins B1 (thiamine hydrochloride) and B6 (pyrodoxin), 100 milligrams, B12 (cyanocobalamin) - 1 mg. Excipients are present in the solution - benzyl alcohol, potassium cyanide (0.25 mg), as well as water for injection.
The drug “Neurorubin Forte Lactab” (tablets) contains thiamine mononitrate - 200 mg, cyanocobalamin - 1 mg, pyridoxine hydrochloride - 50 mg. Also in the drug of this form of release there are auxiliary components. The number of components is indicated per 1 tablet. Auxiliary compounds include: colloidal silicon dioxide, microcrystalline cellulose, pregelatinized starch, magnesium stearate, hypromellose, powdered cellulose, mannitol. The film coatings of Neurorubin tablets contain talc, erythrosine, macrogol-6000, and titanium dioxide.
Pharmacological action of the drug "Neurorubin"
Why is the drug Neurorubin needed? The instruction of the medication explains that it is a drug consisting of a complex of neurotropic vitamins of group B, which are important for the metabolism of proteins, fats and carbohydrates.
Pharmacokinetics and pharmacodynamics of the drug "Neurorubin"
Further, we will talk about what processes in the human body are affected by the components of the drug. The official instructions for use of "Neurorubin" provides a clear description of the action of each of them. Despite the fact that the complex compounds of the drug belong to the same group of vitamins, each of them differs in its inherent spectrum of biological activity. Acting in a complex, they stabilize the nervous system and have a beneficial effect on carbohydrate, fat and lipid metabolism.
Vitamins B1, B6 and B12 are dissolved in water and absorbed by the human body completely immediately after introduction into muscle tissue.
Vitamin B1
Vitamin B1 is actively involved in the metabolism of proteins, fats and carbohydrates. With a lack of thiamine in the human body, the level of lactic and pyruvic acid rises. In this case, vitamin B1 comes to the rescue. Thanks to him, the process of re- and deamination of lactate and pyruvates is launched.
Thus, vitamin B1 normalizes protein metabolism. It also acts as a catalyst in the process of metabolism of fats and their acids, activates ion channels, interacting with cell membranes, and stimulates peristalsis and secretory function in the intestine.
Vitamin B1 is partially excreted from the body in an unchanged state, the rest is evacuated in the form of pyramine and thiamincarboxylic acid.
Vitamin B6
Vitamin B6 actively affects the metabolism of fats and proteins. He also participates in the synthesis of enzymes and hemoglobin. Pyridoxine favors the formation of a myelin neural membrane and is an integral part of lipid metabolism. In addition, vitamin B6 is involved in the process of combining neurotransmitters and hemoglobin in the synapses of the nervous system. Pyridoxine hydrochloride also acts as a coenzyme in enzyme reactions.
Vitamin B6 accumulates mainly in muscle tissue in the form of phosphoric ether. It is excreted from the human body mainly in the state of pyridoxic acid.
Vitamin B12
Vitamin B12 is an indispensable participant in protein metabolism, regulates the production of nucleic and amino acids, purines. Cyanocobalamin is vital for the human body, as it affects the process of myelination of neurons and the production of acetylcholine. In addition, vitamin B12 has a positive effect on the restoration of the fibers of the nervous system and stimulates the production of impulses in its peripheral structures.
Cyanocobalamin is hematopoietin. This means that it promotes the formation of substances in the human body that stimulate the process of maturation of blood cells and normalize the rate of coagulation.
Vitamin B12 is accumulated mainly in the liver and is eliminated from it within about one year.
The drug "Neurorubin": indications for use
The drug "Neurorubin" (tablets) is used to prevent such human health conditions when a deficiency of B vitamins is observed. The medicine is also used to treat the following ailments: diabetic polyneuropathy, neuralgia, intoxication (including alcohol), polyneuritis.
The drug "Neurorubin" (injections) is used as a separate therapeutic agent and in combination with other medicines. By injection, the medicine is administered for the following diseases: neuritis (including chronic and acute), beriberi disease (with wet and dry form), and diabetic polyneuropathy.
Contraindications
Instructions for use "Neurorubin" informs about the contraindication to the use of both forms of the drug in such ailments and conditions: during pregnancy and lactation, under the age of 18 years, with diathesis of an allergic nature, in case of hypersensitivity to the components of the drug. The use of both tablets and Neurorubin injection can lead to complications of psoriasis and aggravation of acne.
Side effects
Are there side effects when using the drug "Neurorubin"? The instruction warns of the possible occurrence of the following deviations:
- headache;
- nausea
- vomiting
- increased irritability;
- gastric bleeding;
- increase in hepatic transmiasis;
- causeless anxiety;
- tachycardia;
- feelings of anxiety;
- sensory neuropathy;
- pulmonary edema;
- itching, rash on the skin;
- circulatory collapse;
- urticaria;
- increased sweating;
- Quincke's edema;
- cyanosis;
- acne development;
- anaphylactic shock.
The drug "Neurorubin": application (dosage and method of use)
The dosage of the drug “Neurorubin” and the duration of therapy are determined by the attending physician, who, when prescribing the drug, is based on the patient’s condition and the nature of the disease.
According to the instructions, the tablet form of the medication is used before, after or during meals. The drug should be swallowed without chewing, washed down with boiled water at room temperature. The therapeutic dose of tablets "Neurorubin" - 1-2 pieces per day.
In the form of injections, the drug "Neurorubin" is administered to relieve pain. Depending on the severity of the disease, injections are given daily or once every two days. The injection solution is injected into the muscle tissue of the buttocks. When the patient's condition improves, the drug "Neurorubin" is used to maintain the therapeutic effect twice during each week.
The duration of the course of taking this medication is one month.
Overdose
In case of exceeding the dosage of the drug "Neurorubin" usually there is an exacerbation of side effects. In this case, the patient is prescribed gastric lavage and therapy depending on the symptoms.
True, isolated cases are known when, with excessive use of this drug, reversible sensory peripheral neuropathy occurred. After discontinuation of the drug, the patient's condition returned to normal.
Interaction of the drug "Neurorubin" with other drugs
On the parallel use with other drugs, the instructions for use of "Neurorubin" says about undesirable joint therapy with the substances Altretamine and Levodopa. The reason is a decrease in their effectiveness with B vitamins.
You should not use the medication "Neurorubin" simultaneously with any form of the therapeutic agent "Isoniazid". Otherwise, the toxic effect of the latter is enhanced.
Medicines “Fluorouracil” and “Thiosemicarbazone” have opposite acting abilities with respect to vitamin B1. Therefore, their parallel use is not recommended.
The simultaneous use of the drug "Neurorubin" with drugs that have antacid and enveloping properties, as they reduce the absorption of the medication we are describing, is also unacceptable.
Terms of sale and storage of the drug "Neurorubin"
The drug "Neurorubin" is sold, the price of which will be indicated later in pharmacies without a prescription.
Pills should be stored at room temperature, which is not lower than +15, but also does not exceed +25 degrees Celsius. The drug should be out of the reach of children. The place where it is located must be dry and protected from direct sunlight. Ampoules with Neurorubin injection should be stored at a temperature of +2 to +8 º.
The shelf life of the drug "Neurorubin" is 48 months from the date of manufacture.
Features of the use of the drug "Neurorubin"
Caution should be taken when using the drug "Neurorubin" for people with angina pectoris or heart failure.
It is extremely rare, but there are cases of development of sensory neuropathy with prolonged use of the drug in large quantities. After stopping the intake of Neurorubin tablets, the patient's condition improves markedly.
In connection with such side effects that occur when using the drug, such as dizziness, anxiety, weakness, anxiety, caution should be exercised in the case of driving vehicles and when performing work that requires a high concentration of attention.
The use of the drug "Neurorubin" during pregnancy and lactation
As mentioned above, during pregnancy and while breastfeeding, it is prohibited to use both tablets and Neurorubin injection solution. In fact, there is no data on the safety of the drug in such cases.
But despite the ban, exceptions happen. The doctor may prescribe the drug "Neurorubin" to a woman during pregnancy or lactation. Sometimes this is permissible in case of emergency, provided that the intended help to the body exceeds the likely harm from the drug. Then, with lactation, it is necessary to interrupt the feeding of the child. Otherwise, the complex of B vitamins will overcome the hematoplacental barrier and under their influence the composition of milk will change. This, of course, will negatively affect the child’s health status.
The drug "Neurorubin": price (tablets and ampoules)
The cost of the Neurorubin vitamin complex depends on the region of the country in which it is sold and on the form of release of the drug. On average, the price of tablets in various regions of Russia starts at 605 rubles.
That's all the background general information about the drug "Neurorubin". The instructions, the price of the drug indicate the high effectiveness of the medication and its accessibility for each patient. The main thing - do not self-medicate, and health will be in order.