"Mifepristone" is a synthetic drug aimed either at preventing pregnancy or at terminating it. Getting into the blood of a woman, he blocks the action of hormones responsible for the onset of pregnancy and its further development. Under its action, the uterus contracts and its inner layer - the endometrium - is rejected.
A fertilized egg is attached to this layer - this is the so-called beginning of pregnancy. If pregnancy has already occurred, the egg is rejected from the body of the woman along with the endometrium.
Indications for use
The drug "Mifepristone", reviews of women indicate that it is used only for forced termination of pregnancy at a short time (up to 6 weeks). After this period, this medicine is prohibited. The effectiveness of the drug is 98%.
In a normal, full-term pregnancy, Mifepristone can be used to stimulate labor.
It is prescribed in the treatment of uterine fibroids.
Used for emergency contraception. Efficiency - 99%.
Dosage and administration
During pregnancy, taking this drug leads to the opening of the uterus and endometrial rejection, usually after 46-48 hours. After two days, the patient is prescribed a prostaglandin preparation, which, together with the Mifepristone medication, helps to reduce the uterus and leads to artificial abortion.
The drug "Mifepristone", reviews of patients say this, is used once in the presence of a doctor. The dose is 600 mg.
After this, the woman is observed by medical personnel without fail for at least 2 hours. After two days, ultrasound control is required, after half a month - repeated ultrasound of the uterus and clinical examination to make sure the fetus is completely removed.
A few years ago, 12 deaths occurred in the United States associated with the use of the drug Mifepristone during childbirth. In all cases, death from toxic shock was recorded. This was explained by a decrease in local immunity in women due to the fact that the prostaglandin analogue was administered by them vaginally.
Contraindications
The drug can be prescribed if a woman does not have a number of contraindications to its use.
Therefore, its use is prohibited if:
- determined individual intolerance to the drug;
- pregnancy is not confirmed or does not exceed 6 weeks (after the cessation of menstruation), or occurred during the use of intrauterine contraceptives, or after the abolition of hormonal contraceptives ;
- there is a suspicion of an ectopic pregnancy;
- a woman has uterine fibroids;
- the patient suffers from renal, adrenal or hepatic insufficiency;
- a woman has inflammatory diseases of the vagina;
- the patient has anemia.
For bronchial asthma, chronic lung disease, high blood pressure, heart failure, the drug Mifepriston (patient reviews and doctors' recommendations say this) should be used carefully. When taking Mifepristone, various side effects can be observed in the form of aching pain in the lower abdomen, weakness, dizziness, and severe headache. 5% of women have excessive uterine bleeding, infection or inflammation of the uterus and appendages. Stool may be disturbed, nausea and vomiting, fever and even allergic reactions of the body in the form of a rash and urticaria can be observed.
The drug "Mifepristone": reviews and recommendations
After using the drug, breastfeeding should be stopped for three days.
After abortion , a new one may immediately occur, which is extremely undesirable. Therefore, the use of contraceptives is necessary.
In pharmacies, you can find the preparations "Mifepristone" and "Mifegin", based on the substance mifepristone.