In the article, we consider the instructions for use with "Fenkarol" for children and adults.
The medication is a histamine receptor blocker. It is able to prevent the development and facilitate the course of various allergic manifestations. It has a pronounced anti-allergic, antiexudative and antipruritic effect, prevents allergic inflammation in the tissues of the body. Against the background of its intake, the effect of histamine is weakened, its effect on vascular permeability decreases, thereby developing a decongestant effect.
Pharmacological forms
According to the instructions, "Fenkarol" is available in two pharmacological forms - in the form of an injection solution, which is used for intramuscular injection, and in the form of tablets.
Fenkarol tablets are round, flat-cylindrical, have a white color, a chamfer is located on one side. Packed in contour packaging, each of which holds 10 tablets.
Injection "Fenkarol" has no color and smell; it is packaged in ampoules containing 1 or 2 ml. Cardboard package contains 10 ampoules. Instructions for use with "Fenkarol" are in each pack.
Structure
The manufacturer produces the drug in tablets of two dosages - 10 and 25 mg. The main active ingredient in the composition is chifenadine hydrochloride. As additional ingredients are used: potato starch, calcium stearate, sucrose.
Each milliliter of the solution intended for intramuscular administration contains 10 mg of chifenadine, the instruction to Fenkarol confirms this. Also included is glutamic acid, injectable water. The drug is able to reduce swelling, have an anti-allergic effect.
Pharmacokinetics and pharmacodynamics
The instruction to “Fenkarol” indicates that the active component in the composition of the medication is the quinuclidyl derivative of carbinol, which is able to reduce the effect of histamine, which is produced as an immune response to an allergen.
Chifenadine is able to block H1 receptors depending on the competitive type. In this case, the activation of the enzyme diamine oxidase. This enzyme breaks down about 30% of histamine. In this regard, the effectiveness of the drug is higher than other allergy medications.
Only an insignificant part of the active component penetrates the blood-brain barrier; practically no effect is made on deamination of serotonin and monoamine oxidase.
The medication is able to relieve spasm that occurs in the smooth muscles of the intestine, itching, uncomfortable sensations that develop with an allergic reaction. Under its influence, hypotensive activity decreases, the normal degree of permeability of the capillary walls is maintained, at the same time there is no obvious effect on the heart muscle and pressure. When compared with the popular pipolfen and diphenhydramine, "Fenkarol" does not inhibit the central nervous system, enters the brain tissue in small quantities. In the event that a patient develops a specific reaction to the active component, the appearance of a weak sedative effect is not excluded.
When administered intramuscularly, after half an hour, the highest concentration of the active component is noted. When using a tablet form - after an hour. The accumulation of chifenadine occurs mainly in the tissues of the liver, lungs and kidneys. After metabolism, metabolites are formed that are excreted in the urine.
Indications for use
In accordance with the instructions to "Fenkarol", for the treatment of allergic reactions, both tablet and injection medication can be used. The latter is preferably used only if an urgent need arises, and an allergic reaction has a severe course.
The tabletted “Fenkarol” is used for hay fever, hives, hay fever, reactions to medications or foods.
In addition, the drug can be used for:
- Reactions that are accompanied by bronchospasm.
- Angioneurotic edema.
- Rhinopathy having an allergic etymology.
- Dermatosis, manifested in the form of neurodermatitis, eczema, skin itching.
Instructions for use with Fenkarol must be strictly followed.
Contraindications
It is strictly forbidden to use the medication if the patient has the following physiological conditions:
- Children's age, if the use of an injectable form of the drug is indicated.
- Lactation.
- Pregnancy (first trimester).
- Hypersensitivity to any of the components present in the composition of the drug.
With caution, the drug should be used if the patient has diseases of the heart and blood vessels, intestines, kidneys, stomach, liver.
What else does the instruction manual for Fenkarol tell us?
Side effects
Against the background of the use of the drug, negative reactions develop extremely rarely. If a patient using the drug has an individual sensitivity to chifenadine, undesirable effects may develop such as:
- Headache.
- Slightly marked inhibition and drowsiness.
- Loss of consciousness.
- Nausea and vomiting.
- Bitter taste in the mouth.
- Indigestion.
- Dry mucous membranes.
In the presence of gastrointestinal pathologies, the likelihood of developing these negative effects increases. If the patient develops any of the side effects, including those not provided for by the instructions for use, he needs to consult an allergist.
This is confirmed by the instructions for tablets "Fenkarol".
Using
The choice of the pharmacological form of the drug is carried out by an allergist, based on the etymology of the disease, its course and the appropriateness of using one form or another.
Tableted "Fenkarol" should be taken after a meal. You can drink it with water or any other liquid. When using "Fenkarol" in a dosage of 25 mg, adult patients should take up to 2 tablets, three or four times a day are taken. The maximum allowed per day to consume 200 mg of the drug.
For children from 12 years old, the total daily dose should not exceed 75 mg. Thus, one tablet should be taken, the multiplicity of receptions - up to three.
The average duration of treatment using this medication is 15 days. Below we consider the instructions for the "Fenkarol" for children.
When using a medication with a dosage of 10 mg, certain schemes should be followed.
- Children from 12 years of age are prescribed 20 mg three times a day.
- Children 7-12 years old according to the instructions for use with Fenkarol - 10 mg each. Reception should be carried out no more than three times a day.
- Children 3-7 years old are shown twice a day for 10 mg.
The duration of therapy should be agreed with the doctor. Most often it is 10-15 days.
When using the injectable "Fenkarol", intended for intramuscular administration, the following treatment regimens should be adhered to:
- During therapy, hay fever should be administered intramuscularly twice a day for three days, 2 ml of solution should be administered. Then the dosage should be reduced by half and continued administration for another two days.
- In the treatment of Quincke's edema and urticaria, it is indicated for 5 days to administer 2 ml twice a day. In a subsequent dose, reduce to 2 ml per day, the introduction is continued for another 3 days.
- For one injection, no more than 2 ml of the drug is allowed. During the day - no more than 4 ml.
To achieve the desired effect and relieve acute allergies, experts recommend switching to the tablet “Fenkarol”.
Overdose
When taking up to 300 mg of the drug during the day, serious disturbances in the functioning of the body do not occur.
An overdose is characterized by the development of the following specific symptoms:
- Stomach ache.
- Indigestion.
- Vomiting
- Nausea.
- Dry mouth.
- Headache.
When symptoms of an overdose appear, the patient should be prescribed symptomatic therapy, give activated charcoal.
Instructions for use with Fenkarol tablets are very detailed.
Interaction with other medicines
The effects of alcohol, as well as drugs with a sedative effect while taking the medication, are not amplified. With the parallel use of medicines with Fenkarol, plasma concentrations of drugs that are slowly absorbed in the stomach, such as coumarins, can change.
Analogs
Currently, there are quite a few remedies, the impact of which is similar to Fenkarol. Among the most popular are worth noting:
- "Altiva";
- Claritin
- Lorano Odt;
- Peritol
- Telfast;
- "Trexil Neo";
- "Fexofast";
- Fribris
- “Friedes”;
- "Erolin";
- Erius
- "Eden";
- Fexofen-Sanovel;
- Fexomax;
- Tigofast;
- Semprex
- Lorizan
- Lordes
- Loratadine
- "Laurent";
- "Ketotifen";
- Kestin
- "Diazolin";
- "Histafen";
- "Alergostop";
- "Alernova";
- "Allergomax";
- "Alersis";
- Alerik
- "Desal";
- Clarisens
- Loratek.
If it is necessary to replace the drug, it is important to consult an allergist and determine the feasibility. Below we consider in more detail the instructions for use with Fenkarol for children.
Use for treating children
For the convenience of dosing the drug for children, the manufacturer produces a special tabletted "Fenkarol" with a dosage of 10 mg. The use of this form of medicine is allowed from 1 year.
Most often, children's “Fenkarol” is used as an emergency aid if the child develops edema on the background of eating any allergenic product.
Cost
The average cost of a tabletted “Fenkarol” with a dosage of 25 mg is 220 rubles per pack containing 20 tablets. The instructions for use with "Fenkarol" is not indicated.
Packaging a child’s product will cost an average of 150 rubles.
Reviews
Most often, there are positive reviews about the experience of using this medication. Patients note that "Fenkarol" is very effective in case of severe bronchospasm, helps eliminate the swelling that accompanies bronchitis, runny nose and acute respiratory infections. Separately, the democratic cost of the drug is noted, a rare manifestation of adverse reactions.
Reviews on the use of the children's version of the drug contain information about its high effectiveness and speed in emergency situations. However, some parents note such negative aspects of the drug as the inability to use for children up to a year, often developing adverse reactions.
It is important to remember that the appointment of medications to combat allergies should be carried out by an allergist. Self-medication can cause complications and undesirable consequences.
We reviewed the instructions for "Fenkarol" for children and adults.