What are the analogues of Nise? The answer to this question will be presented to your attention a little below. We will also tell you about what the mentioned tool is for, what forms it has, how it should be used correctly and so on.
Composition, form, description and packaging
Before listing the analogues of Nise, it is necessary to talk about the drug itself. As you know, it is available in the following forms:
- The tablets are biconvex, round in shape, almost white in color, with a smooth surface of a yellowish tint. The active element of this form is nimesulide. The preparation also includes excipients in the form of MCC, colloidal silicon dioxide, corn starch, magnesium stearate, dibasic calcium phosphate , talc, starch sodium glycolate and polyvinylpyrrolidone. The drug goes on sale in blister packs (10 tablets each), which are placed in a pack of cardboard.
- Suspension "Nise" (analogues cheap really exist). This form is intended for oral administration. The suspension has a yellow color, a pleasant aroma and a characteristic taste. The drug is redispersed with strong shaking. It contains nimesulide, as well as additional elements such as sucrose, purified water, sorbitol, glycerol, methyl paraben, polysorbate 80, propyl paraben, pineapple flavor, xanthan gum, quinoline dye and citric acid. In pharmacies, the drug can be found in dark glass bottles (60 ml each) with a dosing cap (placed in a cardboard box).
- Gel "Nise" (analogues, the price of the drug are listed below). Such a tool is intended for external use. The gel is free of foreign particles. It is transparent, has a light yellow or just yellow color. The preparation contains nimesulide, as well as such auxiliary components as butylhydroxyanisole, N-methyl-2-pyrrolidone, flavoring agent, propylene glycol, water, macrogol, potassium phosphate, isopropanol, thimerosal, carbomer 940. The drug is sold in tubes (20 g), which are in packs of cardboard.
pharmachologic effect
The analogs of Nise have similar properties to it. The drug in question is an NSAID. It is a selective COX-2 inhibitor. The medication has an antipyretic, analgesic and anti-inflammatory effect. It inhibits platelet aggregation and histamine release.
Experts have proven that nimesulide is able to prevent the destruction of cartilage tissue. It has antioxidant properties, and also interacts with glucocorticoid receptors, inhibits the formation of decay products (toxic), helps to eliminate or weaken pain in the joints, reduces swelling and morning stiffness of the latter, and helps increase range of motion.
Indications for use
Analogues of "Nyza" and the drug in question are most often prescribed for the following diseases:
- rheumatoid arthritis;
- psoriatic arthritis;
- articular syndrome with rheumatism and exacerbation of gout;
- ankylosing spondylitis;
- radiculitis;
- osteochondrosis with radicular syndrome;
- lumbago;
- sciatica;
- osteoarthrosis;
- arthralgia;
- myalgia of non-rheumatic and rheumatic origin;
- arthritis of various etiologies;
- post-traumatic inflammation of the soft tissues and disorders of the musculoskeletal system (tears and damage to ligaments, various bruises);
- inflammation of the tendons and ligaments, bursitis;
- fever of various origins (including for infectious and inflammatory diseases);
- pain syndrome of various origins (with injuries, in the postoperative period, toothache, algodismenorea, headache).
Contraindications
The analogue of “Nise” (tablets, gel, suspension), as well as the drug itself, cannot be used for:
- GI bleeding;
- erosive and ulcerative lesions of the gastrointestinal tract;
- "Aspirin triad";
- impaired liver function;
- pregnancy
- severe renal failure;
- lactation (breastfeeding);
- dermatoses, damage to the epidermis, skin infections in the area of application;
- hypersensitivity to nimesulide, as well as other drug substances, acetylsalicylic acid and other NSAIDs;
- in children under two years of age.
What deviations should be used with particular caution to prescribe the drug in question and its analogues? Nise (gel, tablets, suspension) and other NSAIDs are carefully prescribed for patients with arterial hypertension, heart failure, and diabetes mellitus. In the presence of such deviations, the use of the medication should be carried out under the supervision of a doctor.
The drug "Nise": instructions for use
Analogues of this drug can be both cheaper and more expensive. In any case, they effectively help with any pain syndromes.
Nise tablets are prescribed for adults inside 100 mg twice a day.
For children from 2 years of age, the medication is given in the form of a suspension. The recommended dose is 3-5 mg per kg of baby weight. With the ineffectiveness of such a tool, its analogues are used.
Nise is a gel that is intended for external use. Before using it, it is necessary to wash and dry the skin. A column of the drug with a length of about 3 cm is carefully applied (3-4 times a day) to the area of maximum pain. Do not rub the drug.
The duration of use of the drug in question should not exceed 10 days.
Adverse reactions
Does the Nise drug have side effects? Analogs (cheap and expensive), as well as the drug itself often cause the following deviations:
- Heartburn, toxic hepatitis, nausea, increased liver transaminases, vomiting, erosive and ulcerative lesions of the digestive tract, diarrhea, pain in the stomach.
- Dizziness and headache.
- Thrombocytopenia, agranulocytosis, anemia, leukopenia.
- Skin rash, bronchospasm, anaphylactic shock.
- Fluid retention, hematuria, prolonged bleeding time.
- Itching, transient discoloration of the skin, peeling, urticaria.
- Systemic adverse reactions.
special instructions
Before using the drug, you should read the instructions. It says that:
- The drug is prescribed with caution to people with visual impairment and kidney function.
- With prolonged use of the drug, liver and kidney function should be monitored.
- When using the medication in the elderly, adjustment of the dosage regimen is not required.
- The gel-shaped product should be applied only to undamaged areas of the skin, avoiding open wounds.
- It is required to avoid getting the drug on the mucous membranes, and also to use it together with airtight dressings.
- After using the gel, wash your hands with soap. The tube is recommended to be tightly closed.
- Taking Nyce inside can cause drowsiness and dizziness, and therefore it should be used with extreme caution in patients who engage in potentially hazardous activities.
Analogs and prices
The analogue of “Nise” (tablets) may turn out to be both cheaper than the original and more expensive. For example, Aponil tablets cost 130 rubles (20 pcs., 100 mg), and the drug in question costs 220 rubles (20 pcs., 100 mg). As for the similar drugs Nimika and Nimulide, their price is slightly higher and amounts to 235 and 250 rubles, respectively (20 pcs., 100 mg). The cheapest analogue of Nise in the form of tablets is the drug Nimesulide. It can be purchased for 65 rubles (20 pcs., 100 mg).
Now you know what the Nise drug (tablets) is. Analogs, the price of this tool is indicated above. However, such a drug has other forms of release.
A suspension “Nise” (60 ml) costs about 240 rubles, while its analogue “Nimulid” can be purchased for 220 rubles.
As for the gel, it also has many substitute agents. The drug itself costs about 180 rubles (20 g). However, such a medicine does not have cheap analogues.
In general, the following drugs can be distinguished, which are NSAIDs and are used according to the same indications as the Nise drug:
Aktasulid, Flolid, Ameolin, Sulaydin, Aponil, Prolid, Aulin, Novolid, Kokstral, Nimulid, Mesulid, Nimika, Nimesulide ", Pharmaplant", "Nemuleks", "Nimesulide", "Nimesan", "Nimegesic", "Nimesil", "Nimesulide-Teva".
Drug Reviews
According to patients' reviews, the Nise medication quite effectively eliminates any pain syndromes. It also relieves swelling and eliminates swelling. However, it should be noted that along with positive ratings, this drug has negative ones. According to them, such a tool negatively affects the mucous membranes of the digestive tract and often causes adverse reactions. Perhaps that is why experts still do not recommend using the drug to treat children.