Problems with the cardiovascular system in many regions top the list of the most common diseases. However, this is not surprising. Today's abundance of stress, stressful rhythm of life, poor eating habits, inadequate physical activity and poor environmental situation inevitably affect the state of the human internal organs. The heart is an unpretentious organ. However, it also requires some care. In the absence of sufficient amounts of calcium and vitamin C in consumed foods, the heart can also fail prematurely. To avoid such problems or to solve existing ones will help high-quality medications designed for such problems. Your doctor can help you choose them, who knows the features of your disease well. The drug "Ivabradin" is very popular among specialists and patients. However, to start taking some kind of drug, you need to learn about it as much as possible. It is important to find out detailed information about Ivabradin. Price, reviews, analogues - about all this in the article. What makes the product deserve such a spread? What are the features of the use of this drug? Who should not prescribe the drug in question? What medicines and substances should not be combined with it when drawing up a treatment regimen? You can find clear answers to these and other questions later in this article.
Structure
To the constituent components of the drug "Ivabradine" the instruction includes ivabradine as the main active substance. As additional constituents, corn starch, glycerin, red iron oxide, macrogol, yellow iron oxide, lactose, maltodextrin, titanium dioxide, magnesium stearate, hypromellose and colloidal anhydrous silicon dioxide are used.
Release form
The drug "Ivabradine" is produced in the form of tablets, which are coated with a film coating.
Indications for use
There are a number of conditions in which the drug in question is effective. The medication "Ivabradin" instruction recommends use in the following cases:
- coronary heart disease;
- chronic stable angina pectoris;
- reduction of the threat of cardiovascular events;
- chronic heart failure.
In all of the above cases, the use of the drug in question will be effective.
Contraindications
The drug "Ivabradin" the instructions for use prohibit use in the presence of the following contraindications:
- bradycardia;
- myocardial infarction;
- arterial hypertension;
- unstable angina pectoris ;
- cardiogenic shock;
- Syndrome weakness syndrome
- sinoarthrial block;
- liver failure;
- individual intolerance to the individual components of the drug.
It is forbidden to combine with antiviral agents, macrolide antibiotics, nefazodone and antifungal drugs.
Mode of application
Ivabradine tablets are intended for oral use by adults. They should be taken twice daily with meals.
If five milligram tablets are used, then they can be separated. However, seven and a half milligram tablets should not be divided.
In the event that the drug is used to combat coronary heart disease, it is important to take them according to the following guidelines. A single dose is five milligrams. It should be taken twice a day. Depending on how the body responds to this kind of treatment, the working single dose should be increased to seven and a half milligrams. If the reaction to the drug is accompanied by unpleasant consequences, then the dosage must be reduced or canceled therapy. However, only the attending physician should make adjustments to the treatment regimen.
A similar treatment regimen is used, and if the tablets are used to combat chronic heart failure.
Elderly patients should take two and a half milligrams of "Ivabradine" twice a day. If the reaction of the body is positive, then the dose can be gradually increased.
Patients who suffer from mild hepatic insufficiency can take the drug in question in the same doses. If the degree of the disease is moderate, then the patient needs constant monitoring by the attending physician. Patients with a severe degree of liver failure are not allowed to take this drug.
Adverse reactions
The main side effect when using this drug is the appearance of photopsies (special light flashes that temporarily occur in front of the eyes; they can represent a sharp increase in the brightness of the perception of the picture in a certain area of the field of view). As a rule, they appear at those moments when the light intensity suddenly changes. This side effect is characteristic of the first two months of treatment. However, in some cases, they may occur much later.
In a small number of patients, bradycardia was observed in the first two to three months from the start of therapy.
Overdose
Ivabradine tablets are strongly recommended to be taken exclusively at the recommended doses. Exceeding them can lead to undesirable negative consequences. These include severe bradycardia. It should be treated symptomatically in medical facilities with the participation of competent medical personnel. Sometimes even the temporary use of a pacemaker is required.
Application features
"Ivabradine" is not intended for the prevention or control of arrhythmia.
During therapy with the drug in question, it is important to regularly monitor the status of each patient. This will help to avoid any unpleasant consequences.
For those patients who have suffered a stroke, it is not recommended to prescribe this remedy.
It is proved that the drug in question has a significant effect on the functioning of the retina. Although this effect is generally not toxic, its effects are often difficult to predict. Therefore, if you experience any unpleasant consequences for vision, you should immediately stop using this medication and seek help from your doctor.
You can not use the drug in question simultaneously with calcium channel blockers. This reduces the effectiveness of therapy.
Patients who suffer from hypertension should be under the supervision of a competent physician for the entire period of treatment.
The drug in question is not suitable for those patients who suffer from congenital lactose intolerance.
You can not drink grapefruit juice during therapy with Ivabradine. Since this drink significantly increases the concentration of the drug in blood plasma, which dramatically affects its effectiveness.
Effect on reaction rate
How does Ivabradin affect the ability to adequately drive a car and complex mechanisms? The instruction states that this drug does not adversely affect the patient’s consciousness and speed of his reaction. However, when using the drug in question, a short-term visual impairment is possible. They represent the sudden appearance of bright light flashes or somewhat blurred vision. Typically, such symptoms are associated with a sharp change in light intensity and pass on their own after a while. This nuance is important to consider for those who plan to drive a car or work with any mechanisms.
Other drug interactions
The drug "Ivabradin" instructions for use prohibit the use simultaneously with cardiovascular preparations (for example, bepridil, quinidine, ibutilide, sotalol, disopramide and amiodarone), as well as non-cardiovascular substances (such as cisapride, ziprasidone, mefloquin, promozidine, pimozidine, , sertindole, halofantrine).
If such a combination is nevertheless necessary, the patient’s cardiac indices should be constantly monitored in a specialized medical institution.
Use during pregnancy
To use during the period of carrying the child or during breastfeeding "Ivabradin" the instruction strictly prohibits. The drug crosses the placental barrier and into breast milk and, as a result, has an extremely negative effect on the development of the child.
Also, it is not recommended to use this medication for the treatment of children under eighteen years of age, since there is no data on the safety and effectiveness of the drug for this group of patients.
Analogs
Those patients who, for certain reasons, can not take the drug in question, can turn their attention to substitutes for the drug "Ivabradin". Analogs containing the same main active ingredient are numerous. The most popular of these is Coraxan. Other remedies commonly prescribed by specialists are Bravadin, Vivaroxan, and Ryan. All these drugs have similar recommendations for use and, according to reviews, have the same effectiveness.
Reviews
Patients advise Ivabradine as an effective tool, convenient for use. Most of those who use it do not feel any adverse reactions. And the result of the action, on the contrary, is noticeable after the first tablet of the drug "Ivabradine". Reviews confirm its effectiveness. However, all patients emphasize the need for constant consultation with the attending physician in order to avoid any undesirable consequences for the patient.
Shelf life
The drug in question retains its beneficial properties for three years from the date of its manufacture. After this period, the use of the drug may be useless or even dangerous for the patient, therefore, after the expiration date, the use of this medication is prohibited.
Storage and distribution conditions from pharmacies
The medicine "Ivabradin" is different in that it does not lose its beneficial properties under various lighting conditions and temperature conditions, so it is not necessary to create special conditions for its storage. However, it is important to keep the drug in question in a place where children can not get it. The medicine is dispensed from pharmacies exclusively according to the prescription prescribed by the attending physician. The average cost of the drug (for tablets of five milligrams) is about one thousand one hundred forty rubles.
You can use Ivabradine without fear only by carefully studying this article and consulting with a competent specialist. The supervision of the attending physician can be a guarantee of the success of therapy with the participation of the drug in question. Many patients were able to save life only because they strictly adhered to these recommendations and did not neglect communication with their attending physicians. Trying to save on this time can result in a final loss of health. Is there something worth taking such risks for?
Therefore, make sure that you carefully study all the information that relates to the use of the drug "Ivabradine": instructions for use, analogs, contraindications and possible side effects. A responsible approach to choosing a treatment method is usually rewarded with its successful results.
The fact that a person’s well-being largely depends on his state of health is an indisputable fact. Diseases can impose significant limitations on our capabilities and not even give a chance to realize our ideas, desires and undertakings. Be attentive to your health and do not let any disease take control of your life!