The drug "Norbactin" describes the instruction as an antibacterial agent from the fluorochitolone series, which has a broad spectrum bactericidal effect. The medication is active against most bacteria (gram-negative and gram-positive), including strains that are resistant to penicillins, sulfanilamides, tetracyclines, aminoglycosides, cephalosporins. The active component of the drug is norfloxacin.
After oral administration, the active substance from the digestive tract is absorbed quickly. About a third of the drug is excreted in the urine during the day unchanged, a third - with feces. The absorption of the drug slows down with the use of food. In blood plasma, the maximum level is observed within one to two hours after oral (oral) administration of 400 mg of the drug.
The drug "Norbactin." Instruction Appointment
The drug is indicated for infections provoked by bacteria that are sensitive to the active ingredient (norfloxacin). These include, in particular: diseases (uncomplicated and complicated) of the lower and upper parts of the urinary system of chronic and acute course (pyelonephritis, pyelitis, cystitis, cystopyelitis), urinary tract pathologies caused by urological procedures, surgical interventions, and urolithiasis.
The tool "Norbactin" instruction also recommends to patients with severe neutropenia and weak immunity as a prophylaxis of infectious diseases provoked by gram-negative microbes.
Dosage regimen
The drug is prescribed for adults. Recommended on an empty stomach, washed down with water, or with food, twice (in the evening and in the morning). It is allowed to take once a day, but at the same time daily.
The dosage of the drug depends on the severity of the pathology and the sensitivity of the pathogenic microbes. Therefore, it is necessary to determine the degree of sensitivity of microorganisms to norfloxacin. In this case, treatment can be started until the results of bacteriological analysis are obtained.
The drug "Norbactin" for cystitis (uncomplicated, acute) is prescribed in a dose of 400 mg for three days, twice a day. For infections in the urinary tract, the dosage and frequency of administration is the same, the duration of use is from seven to twenty days.
To prevent diseases caused by gram-negative bacteria, patients with weak immunity and severe neutropenia are prescribed 400 mg throughout the course of neutropenia two to three times a day.
In case of recurrent (repeated) infections in the urinary tract of a chronic course, the Norbactin preparation recommends taking 400 mg twice a day for eight to twelve weeks.
Despite the fact that some symptoms of the disease resolve within a day or two, therapy should not be interrupted.
Contraindications
The tool "Norbactin" is not prescribed for hypersensitivity to its components, severe renal failure, with tendonitis or tendon rupture caused by quinolones, children under eighteen years of age.
Medication is not recommended during lactation and during pregnancy.
Adverse reactions
Taking Norbactin may cause diarrhea, abdominal pain, vomiting, nausea, and bitterness in the mouth. With prolonged use, the development of pseudomembranous colitis is likely . The tool "Norbactin" in some cases can provoke disorders of the urinary system (polyuria, dysuria, nephritis and others), central nervous system (dizziness, depression, anxiety, euphoria and others). Fainting conditions were also observed in individual patients.
About the drug "Norbactin" reviews of experts, mostly positive. However, doctors warn that the therapeutic effect is achieved only with strict adherence to the treatment regimen.
Before using the medicine "Norbactin", you should carefully study the annotation, consult a doctor.