Too many women today suffer from infertility. Thanks to modern medicines, you can solve the problem and feel the joy of motherhood. One of the most popular and proven drugs can be called "Rotten." Almost all happy patients leave reviews.
Formula of release and composition of the drug
It is a recombinant human chorionic gonadotropin. The drug is administered subcutaneously and intramuscularly. The drug’s leophilisate is white. To it comes with a bottle of solvent. It is transparent in color and colorless. The main substance of the “Rotted” medicine is human chorionic gonadotropin. Auxiliary components are magnesium hydrogen phosphate, carmellose sodium, mannitol, sodium digitophosphate.
The solvent contains an
isotonic sodium chloride solution. The drug is produced in a dosage of 2 ml. In the box are three ampoules of
dry matter and the same number of ampoules for dissolving the “Rotil” medicine. Reviews show that to achieve the desired pregnancy is obtained in 60% of cases after undergoing therapy.
pharmachologic effect
The medicine “Rotted” contains human chorionic gonadotropin. It has a high degree of similarity with the action of luteinizing hormone. This substance is indispensable for the normal growth and maturation of male and female gametes. LH is also needed to create sex hormones. It is equally useful to both women and the stronger sex. Representatives of the weaker sex, the “Pregnil” drug replaces the formation of the endogenous luteinizing hormone in the middle of the cycle to help complete the phase of the formation of follicles, which are responsible for ovulation.
Also, the medicine is prescribed as a substitute for endogenous LH in the luteal phase. It is no coincidence that the drug “Rotted” reviews more often. Who becomes pregnant immediately after treatment, he tries to recommend the medication to others.
For men, the “Rotted” medicine stimulates the production of Leydig cells. Thanks to timely treatment, it is possible to normalize the level of testosterone in the blood of the stronger sex.
Pharmacokinetics of the drug
The chorionic gonadotropin reaches its highest peak in plasma after injection after eight hours in men and 20 hours in women. There is a big difference between the absorption of a substance after an injection in different sexes. In women, the concentration of the hormone in the body is delayed. This reaction is most associated with increased thickness of adipose tissue in the body.
Almost 80% of the drug is broken down in the kidneys. After one injection, the substance is excreted after 33 hours. So the medicine “Rotted” acts in the female and male body. Instructions, reviews, the correct dosage - all this information should be studied before starting therapy.
Dosage
After diluting the dry matter with a solvent, it is necessary to inject intramuscularly or subcutaneously. To create ovulation in infertility with its complete absence or impaired follicular maturation, a woman is injected with 5,000 to 10,000 IU of the “Rotted” drug.
Has a positive means "Rot 5000" reviews. Those who become pregnant are trying to share important information with women who have not yet experienced the
joys of motherhood. However, self-medication on the recommendation of friends is undesirable. The drug should be prescribed by a specialist.
To complete the treatment with follicle-stimulating agents, it will be enough to make one injection of “Rotted”. Reviews of doctors show that the therapeutic effect occurs within a month. The medicine is administered before ovarian puncture during the hyperstimulation control program. To maintain the formation phase of the corpus luteum, an injection must be made in a dosage of 1000 to 3000 IU. Injections are made on the third, sixth and ninth day of artificially induced ovulation.
In men, with a low content of testosterone in the body, an injection is made in a dose of 1000 to 2000 IU twice a week. With the development of infertility, additional drugs must be added to the “Rotted” drug. For example, the substance "Phyllitropin". It must also be stabbed twice a week. The course can last up to 3 months. In this case, you will have to rely on an increase in spermatogenesis. During treatment with the “Rotted” medicine, it is necessary to abandon testosterone replacement therapy.
The dosage of the drug in childhood
In boys, with a delay in puberty, the “Rotted” remedy is administered at a dose of 1500 IU twice a week for six months. In children under 2 years of age, the drug is administered in a dosage of 250 IU twice a week for 6 weeks. Up to 6 years, the dosage is 500-1000 IU. The course of treatment can be quite long. After 6 years, the dose reaches 1500 IU.
If the therapeutic effect is insufficient, treatment is recommended to be repeated.
Side effects
In very rare cases, a generalized rash or fever may begin. Also at the injection site, a local reaction occurs. It is manifested by swelling, soreness and itching. Women do not often develop thromboembolism after completing a course with the Pregnil 5000 drug. Reviews show that side effects are temporary and go away quickly.
In rare cases,
ovarian hyperstimulation syndrome develops
. There is hydrotox, abdominal pain, diarrhea, nausea, soreness of the mammary glands, a slight
increase in the ovaries and cysts. Weight gain is another unpleasant symptom.
In men and adolescents, when treated with large doses of the “Rotted” drug, water and sodium can be retained in the body. This occurs as a result of an excess of hadrogens. Breast enlargement may be observed.
As you can understand, the drug “Rotted” has many side effects. Reviews of specialists show that the presented symptoms are not dangerous to health. However, they must be reported to the attending physician.
Contraindications to drug treatment
Some patients may develop hypersensitivity to the main substance of the Pregnil drug (gonadotropin) and its auxiliary components. You can not prescribe a remedy for suspected or presence of tumors in women of different etiologies.
In children with early puberty, the medication is not used. Women with the wrong location and development of organs incompatible with pregnancy, the drug is also contraindicated. With caution, medication should be prescribed if the body is prone to thrombosis. Not used for heart and kidney failure. All these contraindications must be taken into account before starting treatment with the Pregnil drug. Reviews of experts show that a positive effect will only be possible if the patient first undergoes a
full examination of the body.Drug Reviews
The drug gives an excellent effect in violation of ovarian maturation, the absence of ovulation in infertility. In men and adolescents with a low testosterone content, the medicine also brings an excellent therapeutic result.
Negative reviews about the drug are also available. They are most often associated with improper medication.
Typically, the remedy presented is used to treat infertility in women. You can often hear good reviews about the Pregnil 5000 drug. Whoever becomes pregnant knows how important timely therapy is.