In the reviews, "Neuromidine" is described as an effective drug for the treatment of diseases associated with disorders of the nervous system. Consider the basic information about the tool: in which cases it is necessary to use it, what contraindications exist and what patients say about this drug.
General information about the drug
The drug "Neuromidin" is supplied to pharmacies in the form of tablets and a solution for injection.
The main active substance of the drug is ipidacrine hydrochloride. The composition of "Neuromidine" includes some additional components. They depend on the form of the product:
- The tablets additionally contain calcium stearate, lactose monohydrate, starch.
- "Neuromidine" in ampoules in addition to the active substance includes water for injection.
The drug should be stored in a cool (not more than 25 degrees) dark place. The shelf life of Neuromidine tablets is 18 months. The solution will become unusable after one year.
From pharmacies, the drug is dispensed only if there is a prescription from a doctor.
Indications for use
As mentioned above, the tool is used to treat various diseases associated with the peripheral nervous system.
For example, it can be:
- neuritis;
- polyneuritis;
- myasthenic syndrome;
- myasthenia gravis;
- polyneuropathy;
- mononeuropathy;
- polyradiculopathy;
- myelopolyradiculitoneuritis.
In what other cases is prescribed "Neuromidine"? Indications are also:
- Mental retardation in children.
- Paresis.
- Bulbar palsy.
- Cerebrovascular accident.
- Disorders of the central nervous system (memory loss, impaired ability to concentrate, disorientation, and so on);
- Alzheimer's disease.
- Weak labor.
- Encephalopathy
Judging by the reviews, “Neuromidine” is also used during treatment as one of the components of complex therapy:
- multiple sclerosis;
- traumatic brain injuries;
- insufficient bowel tone;
- impaired motor activity resulting from organic lesions or injuries.
Contraindications
The medicine "Neuromidin" is not prescribed in cases where the patient has:
- vestibular disorders;
- bradycardia;
- bronchial asthma;
- angina pectoris;
- propensity for vestibular disorders;
- bowel obstruction or urinary tract;
- epilepsy;
- hypersensitivity to the components of the drug.
Also, the drug is not used during pregnancy (the exception is only a weak course of labor) and lactation. The ban group also includes children under the age of 14 years. An exception is made in rare cases and only in the presence of serious diseases, for example, mental retardation.
With great care and under the close supervision of a doctor, "Neuromidine" is used:
- with cardiovascular diseases;
- peptic ulcer of the duodenum and stomach at the stage of their exacerbation;
- lactase deficiency;
- acute respiratory diseases;
- isomaltose or lactose malabsorption syndrome;
- a history of obstructive diseases of the respiratory system;
- lactose intolerance.
Side effects
In the reviews of "Neuromidine" contains information that in some cases, treatment with the drug causes some side effects. In the instructions for use, the manufacturer warns of such phenomena as:
- headache;
- dizziness;
- pain in the epigastric region;
- nausea;
- excessive sweating;
- diarrhea;
- vomiting
- bronchospasm;
- bradycardia
- skin rashes and itching;
- increased salivation;
- increased tone of the uterus.
If they occur, you need to take a break in treatment for 1-2 days, and then reduce the dosage of the drug. It is very important to inform the attending physician!
Overdose
In the case when the patient significantly exceeded the recommended dose of the drug, he may experience a state of cholinergic crisis. The latter is characterized by the appearance of symptoms such as:
- decreased appetite;
- enhanced secretion of glands;
- narrowing of the pupils;
- bronchospasm;
- uncontrolled acts of defecation and urination;
- cramps
- weakness;
- drowsiness;
- lowering blood pressure;
- slow heart rate;
- feelings of anxiety or anxiety;
- increased arousal;
- feeling of fear;
- speech impairment;
- jaundice;
- coma.
To eliminate dangerous symptoms, it is necessary to carry out symptomatic therapy and the introduction of M-anticholinergics ("Atropine", "Metacin", "Cyclodolum" and so on).
Instructions for use
The necessary dosages and duration of treatment with the drug are determined by a specialist individually. They depend on the severity of the disease, as well as some other factors. Therefore, below we consider only the average values:
- Multiple sclerosis treatment lasts 60 days and should be repeated several times a year. Usually in this case, the patient is prescribed to take 1 pill 4 times a day.
- In diseases of the central nervous system, the course of treatment can last from 2 months to six months. The patient is prescribed a 0.5-1 tablet of Neuromidin up to 3 times a day.
- In diseases of the peripheral nervous system, treatment will last about 1-2 months, after which it is imperative to take the same break. The patient will have to take a 0.5-1 tablet of the drug 1-3 times a day. In the presence of severe disorders of neuromuscular conduction, as well as to prevent myasthenia crises, Neuromidin in ampoules is additionally used. First, the patient is injected with 1-2 ml of a solution for injection, and further treatment continues with tablets. In this case, the dose can be increased to 1-2 pills up to 5 times a day.
- In case of impaired motor activity, the course of treatment will be 15 days. The drug will be administered intramuscularly 15 ml twice a day.
- Treatment and prevention of intestinal atony involves the use of the drug for 1-2 weeks. The dosage will look like this: 1 tablet 2-3 times a day.
- In order to stimulate labor, a pregnant woman will be given 20 mg of the drug every hour. In total, 1 to 3 applications are needed.
The duration of treatment and the dosage of the drug for children with mental retardation will be determined individually, taking into account many different factors.
Special instructions and interaction with other substances
When treated with "Neuromidinum" the maximum dose of the active substance should not exceed 200 mg per day.
The patient should refrain from driving and performing work that requires quick reactions and increased concentration of attention.
It is important to remember that alcohol is able to enhance the side effects of the drug, so you need to refrain from drinking it throughout the course of treatment. The same applies to anticholinesterase drugs.
"Neuromidine" is able to enhance the effect of inhibition of the central nervous system when using sedatives. But the action of anesthetics, he noticeably depresses.
The use of the drug with nootropics is allowed.
Analogs
Are there any analogues of Neuromidin? Of course. If such a need arises, the agent can be replaced with other drugs with a similar composition or type of action.
The most famous analogues of "Neuromidine" are:
- "Axamon";
- Amiridine;
- Prozerin;
- Ipigrix;
- "Kalimin 60 N".
In most cases, the cost of analogues is much lower in comparison with Neuromidin. The advisability of a replacement must first consult a doctor.
Reviews about the drug
What do patients and their relatives say about Neuromidin? Reviews are completely different. Some note that the tool did an excellent job and relieved the symptoms of the disease, while others say the complete absence of any result. In addition, in negative reviews, there are often complaints about the occurrence of side effects after the use of Neuromidine (allergic reactions, nausea, and so on), as well as too high a cost of the drug.