Let's look at an elementary situation - you have serious health problems, and the need for medications is increasing every day. But after all, if you are not a very rich person and, moreover, at the moment, also not quite able-bodied, it is quite possible that buying the next remedy could turn into a serious problem for you. What to do? Here generics come to the rescue.
Generic is a drug that has absolutely the same composition and effectiveness as an advertised branded product, but at the same time it is much cheaper. One such drug, representing a new class of immunomodulators, is Natco Pharma Ltd., manufactured in India. The official generic of Revlimid is Lenalid.
Its main active ingredient - lenalidomide - has, in addition to immunomodulatory, also a pronounced anti-angiogenic effect.
Let's consider the use of the drug and its most popular generic to date.
Where can I buy the generic "Revlimida"
Generics, despite the complete analogy of composition and effectiveness with a branded drug, have a lower cost, since a company that has a license for their production does not spend money on technology development, testing, etc. Thanks to this, it is able to maintain its profitability at a lower the price of manufactured drugs.
Since the patient is often unable to buy Revlimid (branded drug), the benefits of this approach can hardly be overestimated. Judge for yourself, the Swiss drug "Revlimid" price, depending on the dosage, it starts from 270,000 rubles, while its generic, manufactured by the Indian company Natko, costs 55,000 rubles. The difference is very noticeable!
Just like the brand drug “Revlimid”, the price of which, of course, cannot but shock, an affordable Indian counterpart can be ordered on the retail website of a large Indian company with a 5-year reputation . The condition for the provision of services is the availability of relevant documents that can confirm the need for modern treatment.
About Genco's Natco Pharma
The Indian company Natco Pharma, producing this generic, is known worldwide. It has its own achievements and developments in the field of pharmacology and also regularly expands the number of drugs produced under license.
The products manufactured by Natko are certified in accordance with the most stringent international standards, including MSA in the UK, FDA in the USA, and PIC in Germany. They are a real panacea for many patients, because all the products of "Natko", meeting international standards, are of low cost, which means they can save the health, and indeed the life of many people suffering from serious illnesses.
Indications for use
The described drug is prescribed for myelodysplastic syndromes, and with a diagnosis "Multiple myeloma", treatment with "Revlimid" can significantly alleviate the condition of the patient.
The named disease is, in fact, a tumor of the plasma cells belonging to the immune system that are formed in the bone marrow. And taking “Revlimid” in conjunction with a small dose of the steroid “Dexamethasone”, based on the data presented at the congress of the American Society of Hematologists, stopped the development of pathology for a longer period than in the case of using only “Dexamethasone”.
How is Revlimid applied?
The described agent is intended for oral administration only. Gelatin capsules must not be chewed or broken. In general, both Revlimid and its generic are taken strictly as prescribed by the doctor, at a certain time, shortly before a meal or immediately after it. The capsule must be washed down with water.
Application features
The initial dose of the drug, as a rule, is 25 mg once a day for 1-21 days of each 28-day cycle. "Dexamethasone", with which this drug is prescribed, is taken 40 mg once a day for 1-4, 9-12 and 17-20 days for 4 initial cycles, and then 40 mg once a day for 1-4 day.
In case of intolerance to the drug, dose adjustment should be performed only by the attending physician!
Interaction with other means
A mutual effect on the metabolism of other drugs and lenalidomide was not found.
There is a decrease in the effectiveness of oral contraceptives taken during the described treatment due to the effects of Dexamethasone, which is prescribed with Revlimid.
Contraindications
Like Revlimid, its analogues are contraindicated:
- during pregnancy;
- breastfeeding;
- if necessary, maintain fertility potential;
- in childhood;
- with hereditary intolerance to lactose (it contains capsules of the drug);
- hypersensitivity to its components.
Side effects
Treatment with Revlimid and its generic can cause adverse reactions. Most often they appear in the form:
- neutropenia (39.4%);
- muscle weakness (27.2%);
- asthenia (17.6%);
- constipation (23.5%);
- muscle cramps (20.1%);
- thrombocytopenia (18.4%);
- anemia (17%);
- diarrhea (14.2%);
- rash (10.2%).
Moreover, the development of thrombocytopenia and neutropenia has the greatest dependence on the dosage of the drug, which allows you to control these processes by reducing the dose.