According to the instructions for use, “Loratadin-Teva” is an anti-allergenic drug that blocks H1-histamine receptors, and also inhibits the effects of histamine on blood vessels and smooth muscles. Also, the tool prevents the onset of the inflammatory process and eliminates the first symptoms of allergies. The drug is not addictive, as well as irritation of the central nervous system. Of the shortcomings, only the rather high cost of Loratadin-Teva tablets can be noted. Instructions for use, reviews, the price of this tool is of interest to many. This medicine belongs to the means of a new generation, it is enough to receive it once a day to completely get rid of the symptoms of any types of allergies.
In this article, we consider the instructions for use and reviews for the drug "Loratadin-Teva".
A little bit about allergies
When an allergy occurs, a reaction occurs of the release of histamines, hormones that are produced in the body, but until a certain time do not make themselves felt. Histamine provokes the development of allergy symptoms, which are well known to us all. It:
- swelling;
- itching
- rhinitis;
- coughing attacks;
- inflamed mucosa and others.
It is possible to remove allergic manifestations only by eliminating the source of the allergy itself. If this is not possible, then antihistamines are used. Their main task is to block H1 receptors and stop the release of histamine, which leads to a decrease in allergy symptoms. Pills "Loratadin-Teva" instructions for use are very detailed.
Release form and composition
The drug is available in the form of white oval tablets. The active ingredient is loratadine. As auxiliary substances are used: lactose monohydrate, corn starch, pregelatinized starch, magnesium stearate.
On one side is a dividing strip and the English letter “L” and “10” are engraved on both sides of the dividing line.
Action taken
As indicated by the instructions for use, “Loratadin-Teva” has an antiallergenic, antipruritic and antiexudative effect, inhibits mast cell degranulation and blocks secondary inflammatory mediators (prostaglandin, leukotriene), in addition, it reduces the expression of cytokines and the adhesion of molecules. The medication is not able to overcome the blood-brain barrier. Virtually no sedative and anticholinergic effects, compatible with any type of food. Unlike other drugs of this group, “Loratadin-Teva” does not affect the functioning of the cardiovascular system and does not cause arrhythmia.
Pharmacokinetics
The medicine, once inside the body, is well absorbed in the stomach. Metabolized in the liver. This process is accompanied by an effect called the first passage through the liver. In patients with undisturbed liver and kidney function, the maximum concentration of the active substance in the body is observed after an hour and a half.
Indications for use
As a drug for symptomatic treatment, “Loratadine” is used for seasonal and perennial allergic rhinitis, chronic urticaria, and other manifestations of allergy.
Contraindications
According to the instructions for use, a contraindication is high sensitivity to the active substance and other components of the drug. In addition, the medication is not prescribed for lactose intolerance, lactase deficiency, glucose-galactose malabsorption, pregnancy, during natural feeding, for children under three years of age. With caution, the drug is used in patients suffering from severe liver failure. What else does the instruction say about Loratadin-Teva tablets?
Dosage
Take orally before meals. Adults and children over twelve years of age (body weight must exceed 30 kg) are prescribed 10 mg once a day. The duration of the drug depends on how long the symptoms of allergy occur. If the patient’s condition has not changed for the better within three days from the start of the medication, this means that loratadine does not have the desired effect and the drug must be replaced. For elderly patients, dosage adjustment is not required. Patients suffering from liver failure, it is shown to take the drug 5 mg once a day every day or 10 mg once every two days. This is confirmed by the instructions supplied with Loratadine-Teva.
Side effects
Side effects can be expressed as headache, nervousness, insomnia or, conversely, drowsiness. Sometimes patients notice an increase in appetite, nausea, pain in the epigastric region, a feeling of dry mouth, and a malfunction in the liver. An allergic reaction may manifest itself as a rash, redness, or anaphylaxis. Patients with a malfunction of the cardiovascular apparatus occasionally feel a rapid heartbeat and tachycardia. But, as stated in the instructions, the use of the drug "Loratadin-Teva" rarely causes these symptoms.
Overdose
Exceeding the dose of the drug is fraught with the appearance of drowsiness, headache, tachycardia. The treatment in this case is symptomatic: gastric lavage and the use of activated charcoal are necessary, and it is also possible to use saline laxative solutions and enterosorbents to quickly remove the drug from the gastrointestinal tract.
Drug interactions
Substances such as erythromycin, ketoconazole, cimetidine, increase the maximum concentration of loratadine and its active metabolite in the blood. Clinical changes of importance are not observed. “Loratadin-Teva” reduces the maximum concentration of erythromycin in blood plasma by 15%. If the drug is taken during meals, this will delay absorption, but the clinical effect as a whole will not change. This drug does not enhance the effect of alcohol.
special instructions
This drug can negatively affect the well-being of patients suffering from liver diseases, since their clearance of loratadine can be reduced. When conducting skin-allergic tests, the administration of “Loratadin-Teva” must be stopped at least 48 hours before, since this antihistamine can reduce or obscure the positive skin reaction to the irritant. If you feel a dry mouth after taking this medicine, you should regularly conduct oral hygiene, as the risk of caries increases. Children under 12 years of age should receive the drug in accordance with the age dosage.
The effect of the drug on the ability to drive vehicles and control mechanisms is described below.
When receiving therapy with this drug, the patient should remember to be careful when driving a car and in the process of controlling complex mechanisms, since various side reactions may appear in the form of sedation, dizziness, which can affect the ability to concentrate and the speed of psychomotor reactions.
Shelf life
The shelf life of this drug is 3 years. After the expiration date indicated on the package, the medicine can not be used.
Storage conditions and price
It is necessary to store this medication at a temperature regime not exceeding 25 ° C, in a dark place inaccessible to children. This is indicated by the instructions for use attached to the Loratadin Teva. Its price is affordable. The drug costs about 200-250 rubles, depending on the region.
Analogs
Many experienced allergy sufferers continue to use Suprastin for stopping allergy symptoms, but it is impossible to say that it is definitely worse or better than the described drug. Of course, the newer “Loratadin” surpasses this drug in its properties, although if it helps you and there are no negative manifestations after it, you can leave it as it is. The disadvantages of Suprastin include the fact that it is necessary to take it 3-4 times a day, and severe drowsiness. In addition, driving after taking this medicine is undesirable. Imported medicine "Claritin" is often prescribed by doctors in private clinics. It really has an effective effect, and besides, it can be used during pregnancy. But in this regard, it should be recalled that the active substance in these drugs is the same, respectively, and the effect will be identical. It should be taken into account that Claritin is a very expensive drug, its cost is significantly higher than that of the domestic Loratadin. The use of such an analogue as "Cetrin" also justifies itself in terms of effectiveness, the effect of the drug can last up to three days.
The mechanism of action here is the same as that of "Loratadin": blocking the H1 receptors, which are responsible for the production of histamine. The action is felt immediately 15 minutes after taking the medicine. The medication should not be taken by pregnant and lactating women, as well as children until they reach the age of 6 years. Cetrin also has a domestic counterpart, Cetirizine. Dosage, indications for use and side effects are the same as the medicines described above, but the price is somewhat lower. The advantage of this medicine is the absence of side effects for the respiratory organs, this makes it possible to use it for bronchitis and pneumonia. Of the contraindications, it is possible to note the impossibility of using the digestive system in diseases.
Many doctors are still replacing new drugs with Diazolin, which has long been the most popular allergy medicine and can be found in every medicine cabinet. The use of this proven remedy justifies itself with minor manifestations of an allergy, for example, with a runny nose. However, it is necessary to monitor the condition, if the effect is not achieved, then the drug must be replaced. Diazolin has several significant drawbacks:
- acts slowly;
- the effect persists for a short time;
- has a sedative effect.
We told you about the most popular allergy medications, which are analogues of “Loratadina-Teva”, which one to give preference to, you choose.