Tablets "Misoprostol" - a drug that has a gastroprotective effect. The medication helps to increase the production of bicarbonate and protective mucus, increase blood flow in the mucosa. The drug "Misoprostol" (the instruction contains such data) accelerates the healing process of stomach ulcers or duodenal ulcers, erosion, and also in some cases prevents their formation. The tool has an effect on parietal cells in the stomach. The activity of the drug is noted thirty minutes after administration. Duration of action - from 3 to 6 hours. The medication helps to reduce the myometrium in the smooth muscles, expands the uterine neck. Against the background of oral administration, rapid and complete absorption is observed. Eating lowers absorption. The drug is metabolized in the liver and walls of the digestive tract.
The medicine "Misoprostol." Instruction Appointment
A remedy is recommended for the treatment and prevention of peptic ulcer of the duodenum and stomach, gastrointestinal ulcer due to the use of NSAIDs. In combination with the medicine "Mifepristone", the medication is prescribed to terminate pregnancy in the early stages (up to 42 days). The drug "Misoprostol" (instructions indicate this) is recommended for exacerbation of gastrointestinal ulcer, erosive gastroduodenitis.
Contraindications
Do not prescribe a medicine as a gastroprotective agent during pregnancy. The contraindications of the drug "Misoprostol" (reviews of experts confirm this) include the age of eighteen years, the period of feeding, hypersensitivity. When prescribed for abortion, the drug is not recommended for anemia, hormone-dependent tumors, arterial hypertension, pathologies of the cardiovascular system. Do not prescribe medication for diseases of the liver or kidneys, bronchial asthma, with the use of intrauterine devices (the device is removed before treatment). Contraindications include endocrine pathologies ( adrenal dysfunction, diabetes), glaucoma, suspected ectopic pregnancy. Caution when prescribed as a gastroprotective drug should be observed for inflammation in the intestine and other conditions predisposing to diarrhea. Dose adjustment is necessary if there is a chance of developing dehydration, epilepsy, hematopoiesis, and ischemic heart disease.
The drug "Misoprostol." Instructions for use
As a gastroprotective agent, a medication is prescribed with meals. For the prevention of NSAID gastropathy, a drug is recommended at a dose of 400-800 mcg / day. The amount of funds is divided into 2-4 doses. It is recommended to drink the drug simultaneously with NSAIDs and continue to use throughout the course of NSAIDs. In the treatment of peptic ulcer and gastroduodenitis of an erosive type, 800 mcg / day is prescribed in two or four doses. The duration of therapy is at least a month. To terminate the pregnancy, 400 mcg of the drug is prescribed 36-48 hours after taking 600 mg of the Mifepristone medication.