Ointment "Hepatrombin G" is a medication with antithrombotic and regenerative effects for external use. This combined medication has, in addition to the above, anticoagulant (slowing down blood coagulation), anti-inflammatory and anti-edematous properties.
In the composition of the above funds there is heparin - an anticoagulant of direct effect, inhibiting the activity of the coagulation function. This substance is extracted from the lungs of cattle. Heparin suppresses the reactions that cause blood coagulation and the formation of blood clots, it enhances blood supply, helps to remove stagnant fluid and harmful products from metabolism from the tissues.
The composition of the ointment “Hepatrombin G” enhances the properties of heparin, improves its penetration, protects the skin and, in addition, is an antihemorrhoidal agent. Prednisone, also present in the composition of this medication, reduces the inflammatory process and eliminates pain. The drug scleroses hemorrhoidal nodes (helps to glue their walls with subsequent drying of the node) and has a local anesthetic effect.
Composition and packaging
According to the instructions, hepatrombin G ointment is made in the form of an ointment for rectal and external use. The composition of the medication includes such active elements as heparin sodium, prednisolone acetate, lauromacrogol. In addition, there are some additional substances:
- hard paraffin;
- viscous paraffin;
- colloidal silicon dioxide;
- anhydrous lanolin.
Ointment “Hepatrombin G” is represented by a yellowish-white translucent gel-like mass with a specific odor. It is packaged in 20 g in aluminum tubes with holes protected by the same aluminum membrane. The special cover is equipped with a device for removing the membrane. The kit also contains a tip for rectal administration. The medicine is packed in cardboard boxes.
Indications for appointment
As indicated by the instructions for the ointment "Hepatrombin G", the use of the named medication is recommended for the following pathologies:
- thrombosis (the formation of blood clots in the lumen of blood vessels);
- thrombophlebitis (thrombosis with the formation of a thrombus blocking the lumen of an inflamed vein);
- varicose veins;
- trophic ulcers of the leg;
- tenosynovitis (inflammation of the connective membranes of the tendon);
- inflammatory infiltrates (accumulation of cellular elements with an admixture of blood and lymph in the tissues);
- lymph magnet (inflammation of the lymph nodes);
- mastitis (inflammation of the mammary glands);
- furunculosis (acute inflammatory process in the area of the hair sac and surrounding tissues);
- carbunculosis (purulent-necrotic change in the area of the group of hair sacs).
According to clinical trials, the medicine "Hepatrombin G" is effective in the treatment of sports injuries. In addition, it is prescribed for internal and external hemorrhoids, thrombophlebitis of the veins of the anus, eczema, fistulas, itching and cracks in the anus.
Dosage regimen and drug use
The use of ointment "Hepatrombin G" has some features:
- It is applied in the form of a column (approximately 5 cm) up to 3 times a day, directly on problem areas.
- For vascular diseases, the ointment is used with a bandage.
- Therapy of trophic ulcers involves applying an ointment in the form of a ring, with a diameter of about 4 centimeters.
- When treating leg veins, the medicine is rubbed with light movements, while it is recommended that a single dosage be applied in small portions.
- In the treatment of carbuncles and boils, the best effect is the use of gauze compresses with ointment. After eliminating the pain, the drug is used for a week 1 time per day.
- To administer the ointment, it is necessary to rectally use the attached tip, which facilitates the process of applying the medication.
Ointment is not recommended for more than two weeks, since prolonged use of the drug can provoke the occurrence of systemic adverse reactions.
The use of ointment "Hepatrombin G" during pregnancy and lactation
In the first trimester of pregnancy, the use of this medication in any of its pharmacological forms is contraindicated, since during this period the laying of the internal organs of the unborn child occurs, and the effect of the drug can lead to impaired embryogenesis.
The use of Hepatrombin G ointment during pregnancy in the second and third trimesters is possible only in cases where its potential benefit to a woman is higher than the possible risk to the fetus. The medicine in this case is used under the strict supervision of a specialist and in minimum dosages. The use of the described medication during lactation is possible only after the permission of the doctor. This is confirmed by the instructions for the ointment "Hepatrombin G" for hemorrhoids.
Side effects
With proper use and compliance with dosages, the drug is well tolerated by patients. Side effects can occur and develop with individual sensitivity to the constituent elements of the ointment or its use for too long. Often, the following negative phenomena occur in patients:
- allergic reactions - burning and itching at the place of application of the drug or in the rectum after administration of the ointment;
- local redness of the skin;
- angioedema or urticaria.
Overdose symptoms
During the use of the medication for more than 14 days, signs of an overdose may develop, which are caused by the influence of heparin and prednisolone. These phenomena are manifested in the following:
- a tendency to develop bleeding, bleeding disorders;
- excessive sweating
- impaired adrenal function;
- cardiopalmus;
- change in blood pressure and dizziness.
Drug interaction
The instructions for the use of ointment “Hepatrombin G” reports that with the parallel use of a medication in any pharmacological form with medicines from the class of anti-inflammatory non-steroid drugs, the risk of bleeding increases in patients.
With the concomitant use of this pharmacological agent with anticoagulants, a transformation of the clinical picture of the blood is noted and the risk of bleeding significantly increases. The described tool is not recommended to be used simultaneously with prednisone or other hormones, since this can lead to serious changes in the endocrine system, in particular organs such as the adrenal glands, pancreas and thyroid gland.
Special recommendations
Ointment from hemorrhoids "Hepatrombin G" is not able to adversely affect the central nervous system, therefore, does not affect the speed of mental and motor reactions. The medicament in question in the form of an ointment should be prescribed with some caution to patients with impaired liver and kidney function.
Price
The approximate cost of the drug is 240 rubles. It depends on the region and the manufacturer of the drug. The instructions for use of the ointment "Hepatrombin G" do not contain such information.
Analogs
The following medicines are considered similar in therapeutic effect:
- "Hepalpan" is a combined remedy, the effect of which is due to the properties of its active components. It reduces blood coagulation and thrombus formation in the vascular wall (due to heparin), stimulates and has a keratolytic effect (due to allantoin). The dexpanthenol present in the composition stimulates epithelization (regeneration of the skin surface) and tissue repair.
- “Vazoket” is a medication based on diosmin, which has a venotonic effect (reduces the extensibility of veins), increases venous tone, reduces blood stasis in the veins, and improves lymphatic drainage. This drug normalizes microcirculation, reduces the adhesion of leukocytes to venous walls and their migration into paravenous tissues. It stabilizes the diffusion of oxygen, has an anti-inflammatory effect. "Vazoket" enhances the vasoconstrictor properties of adrenaline, serotonin, norepinephrine, inhibits the production of free radicals, the production of thromboxane and prostaglandins.
- "Phlebodia" - this pharmacological agent belongs to the category of angioprotectors and is used in the treatment of venous diseases. The main substance of this medicine helps to normalize microcirculation, helps restore blood vessels that have lost tone. The drug is used to treat varicose veins and hemorrhoids, but is also used for other negative conditions associated with impaired blood and lymph circulation.
- “Butadion” - NSAIDs from the category of pyrazolone derivatives. It has an analgesic, anti-inflammatory and antipyretic effect, which is due to inhibition of COX activity and a decrease in prostaglandin synthesis.
- “Venarus” is a venotonic and venoprotective pharmacological agent that exerts an angioprotective effect. Reduces the extensibility of veins, significantly increases their tone and prevents venous congestion. Reduces the permeability and fragility of capillaries, increases their resistance. The medicine improves microcirculation and lymphatic drainage. With systematic use, it eliminates the clinical manifestations of venous insufficiency of a functional and organic nature.
So, we examined the instructions for use for the hepatrombin G ointment.
Reviews about the drug
The named pharmacological agent is today widely used in the treatment of a variety of venous disorders associated with inflammation of the veins and the formation of blood clots. Often it is used to reduce the severity of hemorrhoids, both internal and external forms of manifestation.
Patients with this drug are satisfied and note that after treatment with this ointment, their veins have significantly improved. They argue that with regular use, pain in the area of varicose veins was reduced or even disappeared, faster recovery of inflamed skin areas associated with inadequate blood circulation.
It should also be noted that patients, especially women, who most often suffer from such pathological conditions, noted the lightness appearing in the legs and that their manifestation of morning swelling of the legs significantly decreased.
About the ointment "Hepatrombin G", instructions for use and customer reviews about which we presented in this article, some patients have developed a negative opinion. As a rule, we are talking about the poor tolerance of this medication. At the same time, patients noted that they had symptoms of dizziness, mild nausea, and a bitter taste in the mouth. In addition, a small group of patients claims that the drug practically did not help them get rid of the manifestations of the disease.