The drug "No-Shpa" is the most popular tool that helps eliminate spasms of smooth muscles. The spectrum of action of this antispasmodic is quite wide. It helps eliminate spasms of muscles and other tissues. In addition, it is used during preliminary medical preparation before conducting some medical manipulations.
A big plus of this drug is a small number of side effects in comparison with some other types of antispasmodics.
Features of the drug
According to the instructions for use, “No-Shpa” is an antispasmodic that has a powerful effect on smooth muscles to eliminate or reduce the intensity of spasms. This is due to the fact that the drug has an intense inhibitory effect on certain enzymes.
It is worth noting that this drug does not cause almost any side effects from the cardiovascular system. The active substance, which is part of the drug, has a relaxing effect on the muscles of the gastrointestinal tract, genitourinary system, as well as the biliary tract.
Coming inside, No-Shpa is completely absorbed in a short period of time. The maximum possible therapeutic effect is achieved in about 30-45 minutes. Complete elimination of the active substance from the body occurs within 3 days.
Composition and form of release
The drug "No-Shpa" is available in the form of capsules, tablets and a solution for injection. Each of the forms contains the active substance drotaverine, as well as some auxiliary components.
The tablet form is presented in the form of yellow-green or orange pills. One tablet contains 40 mg of the active ingredient. The medicine in tablet form is prescribed for muscle spasms, as well as diseases such as:
- cystitis;
- cholecystitis;
- pyelitis;
- cholangitis and many other diseases.
In addition, according to the instructions for use, No-Shpa tablets are prescribed to eliminate cramps in diseases of the intestines and stomach, and also as an anesthetic for headaches provoked by vasospasm.
The solution for injection is used if taking the drug in tablet form for some reason is not possible. It is worth noting that this tool does not contain lactose, so it can be used to eliminate spasms for patients with its intolerance. According to the instructions for use, No-Shpy injections are prescribed for patients with impaired glucose absorption, lactose deficiency. In addition, the drug is recommended for use with pancreatitis, which is complicated by severe vomiting.
Indications for use
The instructions for use of No-Shpe indicate that this drug is used to eliminate cramping in the presence of diseases:
- bile ducts;
- urinary system;
- gastrointestinal tract.
In particular, this drug is prescribed in the presence of biliary tract diseases, in particular, such as:
- cholangiolithiasis;
- papillitis;
- cholecystolithiasis.
In tablet form, this drug is used to treat diseases of the urinary system, in particular, such as:
- nephrolithiasis;
- bladder cramps;
- urethrolithiasis.
In the form of injections, the drug is prescribed for tenesmus of the bladder. In addition, No-Shpa can be prescribed as an adjunct in the treatment of diseases of the stomach and intestines, which are accompanied by intense spasms. However, peritonitis, acute pancreatitis, as well as ulcer perforation, must first be excluded.
According to the instructions for use, No-Shpa tablets for adults can be prescribed for tension headaches. However, it must be borne in mind that the drug does not help with headaches provoked by an increase in pressure, as well as migraines. Also, the drug can be used to eliminate menstrual pain.
Dosage of medication
According to the instructions for use with “No-Shpe”, self-medication is allowed, without prescribing a doctor for 1-2 days. However, if during this time it was not possible to achieve a decrease in the pain effect, you need to see a doctor for a comprehensive diagnosis.
The instructions for the use of No-Shpa tablets state that the daily dosage for oral administration should be no more than 120-240 mg. At the same time, it must be divided into several parts. It is worth noting that, according to the instructions for the use of No-Shpa tablets, the dosage for single use should be no more than 80 mg. Adult patients are recommended to take 1-2 tablets 2-3 times a day.
The instructions for the use of No-Shpy in ampoules indicate that the use of this drug is contraindicated for patients under 18 years of age. For adults, the maximum daily and single dose of the drug is exactly the same as the tablets. The introduction of the drug is carried out in 1-3 doses. It is worth noting that the dosage of the drug is determined individually within the maximum daily amount. The course of therapy is also determined by the severity of pain symptoms in the patient.
Pregnancy
During the bearing of the child, it is important to choose the right medicine to eliminate the problems that arise. They should give the maximum possible result, but at the same time be safe so as not to harm the unborn baby.
Experts have proved that taking No-Shpy during pregnancy does not harm the fetus at all and recommend using this remedy to eliminate the increased tone of the uterus. This reduces the risk of premature termination of pregnancy. It is worth noting that, according to the instructions for use, “No-Shpu” in ampoules during pregnancy is not recommended.
In the third trimester of pregnancy, before taking the medicine, you must consult with your doctor and appreciate all the advantages and possible risks for the baby, since the active components of the drug can penetrate the blood-brain barrier. Doctors do not recommend using this drug during delivery to relieve pain, as there is a high risk of severe bleeding.
Use in childhood
As stated in the instructions for use, No-Shpa tablets are not prescribed for children under 1 year of age, however, some parents ignore this and give this drug to the child with intestinal colic. Basically, this drug does not provoke any side effects. In small amounts, the active substance of the drug is mixed with breast milk and has a fairly mild effect. However, it is best to consult a doctor before taking it.
According to the instructions for use, the dosage of No-Shpa tablets for the child is calculated by the attending doctor. Children 1-6 years old can use the drug in an amount of 40-200 mg of the drug, divided into 2-3 doses. As stated in the instructions for use, "No-Shpa" for children over 6 years of age is prescribed in a dosage of 80-200 mg, divided into 2-5 doses.
Contraindications
In the instructions for the use of No-Shpy, it is contraindicated for adults and children to use this medication if:
- hypersensitivity to active components;
- impaired functioning of the kidneys or liver;
- hypersensitivity to additional components of the injection;
- genetic intolerance to lactase, galactose;
- chronic heart failure.
If there is a need for the use of No-Shpa in patients with low blood pressure or hypotension, the medicine should be used very carefully, since there is a high probability of collapse.
As for the use of the drug during pregnancy, only the attending doctor should decide this question. With lactation, women need to abandon breastfeeding for the period of treatment.
Side effects
Despite the fact that No-Shpa is widely used for pain, the instructions for use indicate that this drug can provoke certain side effects. However, it is worth noting that they rarely occur, and also have a predominantly short nature.
On the part of the cardiovascular system, a decrease in pressure, as well as a rapid heartbeat, can sometimes be observed. In addition, side effects can be in the form of:
- dizziness
- headaches;
- nausea
- insomnia
- constipation.
Side effects from the immune system are expressed in the form of allergic reactions, in particular, such as:
- hives;
- skin rashes;
- angioedema;
- itching
According to the instructions for use, No-Shpa injections can provoke local allergic reactions, which manifest as redness and slight swelling at the injection site. There is also evidence that many patients developed anaphylactic shock when using the drug, which in some cases ended in the death of the patient.
Overdose
An overdose of the No-Shpa preparation can provoke paralysis of the respiratory center, dangerous cardiac conduction disturbances, as well as arrhythmia. Such pathologies can lead to blockade of the legs of the bundle of His and cardiac arrest.
If there is a suspicion of an overdose, you must leave the patient for several days under medical supervision. If necessary, try to artificially induce vomiting, gastric lavage, as well as symptomatic therapy aimed at restoring existing disorders of the body.
Interaction with other drugs
According to the instructions for the use of No-Shpa, along with other antispasmodic drugs, in particular anticholinergic drugs, their effect is significantly enhanced. The antispasmodic effect is also enhanced by the use of phenobarbital.
The drug "No-Shpa" does not provoke the occurrence of side effects while using it with an analgesic. This allows, if necessary, to carry out combination therapy, combining the vasodilator effect with pain medication. “No-Shpa” injections, administered intramuscularly or intravenously, slightly decrease the activity of morphine. It is necessary to combine this medicine with the Levopoda preparation with caution, since with their simultaneous use the effect of the latter decreases, and as a result, the patient has an increase in tremor.
There is the possibility of taking "No-Shpy" with drugs that interact with plasma proteins. However, it is worth noting that their simultaneous administration can lead to the fact that a stronger drug can displace a less powerful drug, increasing its concentration in the blood. As a result of this, various side effects may occur.
special instructions
Before using the No-Shpa drug, the instructions for use, reviews and analogues should be studied first so that side effects can be prevented. In addition, it is necessary to take into account the peculiarity of the use of the drug. With intravenous or intramuscular administration of the drug, one must remember that the composition of the solution for injection includes sodium metabisulfate, which can provoke very strong allergic reactions. In addition, No-Shpa can cause bronchospasm or anaphylactic manifestations.
With the intravenous administration of the drug, patients who suffer from hypotension should be placed strictly horizontally, as well as periodically monitor the pressure, as there is a high risk of developing angiogenic collapse.
Since taking No-Shpy can provoke short dizziness or a drop in pressure, it is not recommended to drive vehicles or engage in dangerous types of work in the first period of taking the drug that require quick response and increased attention. Such side effects do not occur in every patient, the degree of restriction in this case largely depends on the individual characteristics of the body.
“No-Shpa” tablets should be taken very carefully for people with lactose intolerance, as this drug can provoke gastrointestinal disturbances. With a sharp cessation of taking this drug, withdrawal syndrome may occur, which manifests itself in the form of an exacerbation of the underlying disease. That is why with prolonged use, the medicine should be canceled gradually.
It is worth noting that the combination of the No-Shpa drug with alcohol is unacceptable, since alcohol reduces muscle tone, distorting the effect of the main active component.
Analogues of the drug
Analogues of the drug are used to treat the same diseases as the original drug, but they are made on the basis of other active components. Before choosing “No-Shpa” analogues, the instructions for using each such medicine should be studied carefully. Such drugs may have various pharmacological qualities and side effects, and also differs in therapeutic effect and pharmacokinetics.
The most common analogs include the group of myotropic antispasmodics, the main active component of which is papaverine. These drugs by their action are closest to No-Spee in their pharmacological qualities and are very popular because they have an affordable cost. However, drugs that include papaverine have a much lower effectiveness. In addition, among the substitutes "No-Shpa" you need to highlight such as:
- "Papazol".
- "Trimedat."
- Niaspam.
However, it is worth noting that all these drugs are inferior to No-Shpe in the versatility of the spectrum of action. So, "Trimepbutin" and "Mebeverin" have a very weak antispasmodic effect on the muscles of the urinary system and uterus. The main advantages of the drug "Mebeverin" include the fact that it does not have too many side effects.
Among the analogues of No-Shpa, Papaverine should be singled out. Both of these drugs are antispasmodics of myotropic action. They help lower muscle tone and widen blood vessels. Due to this, muscle cramps are quickly eliminated. It is worth noting that Papaverine is poorly soluble in water, and also has a slightly lower effectiveness. It is best to take this medicine rectally or intravenously.
Among the analogues of No-Shpa, doctors distinguish Drotaverin, however, it is worth noting that such a drug has more pronounced side effects and can harm health.
Qualitative antispasmodics also include drugs such as Spazmonet and Spazmol. Miotrobny antispasmodic "Spazmol" is made on the basis of drotaverinum. That is why this drug has exactly the same scope and effectiveness. The dosage of this drug is 1-2 tablets 2-3 times a day for an adult.
The antispasmodic "Spazmonet" also basically has drotaverinum. This drug is used for spasms of smooth muscles. This medicine has almost the same contraindications and side effects as No-Shpa.
Drug Reviews
Before using the medicine, the instructions for the use of No-Shpy and the reviews about this medicine should be studied very carefully in order to understand exactly whether this medication can be used. Patient reviews about the drug are mostly positive and often doctors recommend this medicine to eliminate cramping. According to available reviews, the drug begins to act literally 10-15 minutes after administration.
Many people not only write about the effectiveness of the drug, but also recommend it to all those who want to very quickly and effectively get rid of existing painful sensations. However, there are also negative reviews, as some patients say that the drug did not have the desired effect. All this is important to consider, so that taking the medicine does not provoke a sharp deterioration in well-being.