Lichen, fungi and other parasitic diseases should be treated immediately. This is due to the fact that such lesions tend to spread rapidly to healthy areas of the body, as well as be transmitted to other people.
To protect themselves and their family members, doctors recommend using a drug like Griseofulvin. Instructions for use, price, reviews of contraindications and indications of the drug in question will be presented below.
Composition, form, packaging and description
In what form is the Griseofulvin medicine sold? Customer reviews report that most often this tool can be found in the form of tablets. They have a white color with a creamy tint, as well as a bitter and not very pleasant taste.
The main active ingredient of this drug is griseofulvin. It goes on sale in contour cells, which are enclosed in cardboard bundles.
It should also be noted that this medication is available in the form of liniment. It consists of griseofulvin and salicylic acid. The drug for local use is sold in banks.
Drug characterization
The drug "Griseofulvin" is an antifungal antibiotic that has a fungistatic effect (that is, it helps to stop the growth of parasitic fungi) on:
- various types of dermatomycetes that cause skin diseases in humans;
- microsporums or parasitic fungi that are the causative agents of microsporia in humans ;
- trichophytons - causative agents of trichophytosis, causing diseases of the nails and scalp;
- epidermophytons - causative agents of epidermophytosis (i.e., inflammatory lesions of the skin of the feet, inguinal region and nails).
It is impossible not to say that the Griseofulvin medication (patient reviews will be presented below) has almost no effect on candidiasis, that is, a disease caused by yeast-like fungi.
An important feature of this tool is its effectiveness when taken orally.
It should also be noted that the activity of the drug to some extent depends on the degree of grinding of its crystals and the specific surface of the powder.
Experts say that the finely crystalline form of this medication is half as active as a specially made, highly dispersed form.
Modern pharmacists mainly use a highly ground preparation, in which the particle size does not exceed 4 microns.
Kinetic properties
How is the absorption of the oral preparation "Griseofulvin"? Reviews of doctors indicate that this tool is perfectly absorbed through the intestines. In the human body, it shows a pronounced tropism to the hair, the horny lipophilic layer of the skin, as well as the tissues of the nail plates.
Due to these properties, the medication in question reaches a high concentration in the lesions.
Metabolized "Griseofulvin" in the liver, and excreted through the intestines and kidneys. The half-life of the drug is exactly one day.
Indications
What is the purpose of using Griseofulvin? Reviews (this medicine treats very well the nail fungus) experts report that the medication in question is one of the effective means of treating people with dermatomycoses (that is, fungal diseases on the skin). It is also prescribed for the treatment of favus (fungal diseases of the skin and head), microsporia (parasitic fungal diseases), trichophytosis and epidermophytosis.
It should be noted that this drug treats skin diseases that were caused by trichophyton (that is, the causative agent of ringworm), and lesions of the nail plates (onychomycosis) caused by pathogenic fungi.
Contraindications
Can “Griseofulvin” be prescribed to children? Reviews of experts report that such a medication can be used in relation to a child, but only for strict indications.
It should also be noted that this drug is not prescribed for patients with severe leukopenia and systemic blood diseases, as well as organic diseases of the kidneys and liver, porphyrin disease (that is, with hereditary diseases associated with impaired pigment metabolism), pregnancy, malignant neoplasms and breastfeeding.
In addition, the tool in question is contraindicated for use outside the hospital, for pilots, drivers of vehicles and people engaged in high-altitude work.
Instructions for use
How is Griseofulvin assigned to a child? The use of tablets is indicated with one dessert spoon of vegetable oil.
With microsporia, children are prescribed 21-22 mg / kg of weight per day. For adults, the drug is recommended to be used in the amount of 8 tablets per day.
The duration of therapy is determined as follows: tablets are taken every day until the test results for mushrooms are negative. After this, the dose is maintained for another two weeks. But at the same time, the drug is taken in a day. Two weeks later, the frequency of taking the tablets is twice every seven days.
With infiltrative suppurative trichophytosis and favus for adults, the medication is prescribed in the same dose and according to the same scheme. As for children, then for them the dosage needs to be changed (18 mg / kg per day).
In the treatment of head mycoses, one should shave the hair once a week, and also wash it with soap twice every seven days.
The dosage for such a lesion depends on the person’s body weight. With a weight of up to 50 kg, the drug is taken in the amount of five tablets. With a body weight exceeding that indicated, for every 10 kg one more tablet is added, but not more than 1 g per day.
The daily dosage for children is calculated using the formula 16 mg / kg.
How to treat onychomycosis with Griseofulvin (3 years old child)? Reviews of experts say that the treatment of such lesions is carried out according to the following scheme: the medication is taken every day for a month. From the second month, he is prescribed once every two days, and then they switch to reception twice a week.
The duration of therapy is 8 months or more.
With severe lesions of the nails, the appointment of tablets should be combined with local therapy.
Liniment "Griseofulvin" is applied to localized skin lesions on their own, and also used in combination with tablets (for extensive lesions).
The ointment is applied to the integument with a thin layer twice a day for three weeks.
Side effects
What adverse reactions can cause the drug "Griseofulvin"? Customer reviews report that this tool affects the functioning of the digestive tract. Patients often complain of pain in the epigastric region, nausea and vomiting. Sometimes the patient may have a stool disorder.
It should also be noted that the central nervous system may cause dizziness, headaches, asthenovegetative and neurological symptoms.
Very rarely, photosensitization develops in patients and disturbances in the hematopoietic system occur. In this case, you must stop taking the medicine.
Analogs
What can replace the drug "Griseofulvin"? Reviews of experts report that this medication is similar to such drugs as Lamican and Terbinafine. However, they should be used only as directed by the doctor.
The drug "Griseofulvin": reviews
Real reviews of doctors about pills and ointments "Griseofulvin" indicate that this tool is highly effective and effective. Patients fully agree with them. They claim that after several doses of the drug, the severity of fungal lesions decreases.
The only drawback of the drug in question is that it can cause unpleasant reactions from the digestive tract.