Many patients suffering from diseases of the musculoskeletal system know firsthand what Hondra-Force is. Tablets and ointment, produced under this name, can be purchased at any pharmacy.
In this article we will tell you about how to use the drug in question, in which cases it is prescribed most often, what patients report about it.
Composition, shape, packaging
The mentioned medication can be purchased at the pharmacy in such forms as:
- Oral preparation "Hondra-Force" (capsules). The active ingredients of this form are: chondroitin sulfate and glucosamine hydrochloride. Also, the composition of the drug includes auxiliary components.
- The drug for external use is Hondra-Force (ointment). The active substance of this form is chondroitin sodium sulfate. In addition, the composition of this tool includes additional elements in the form of dimethyl sulfoxide, white soft paraffin, lanolin and purified water.
The medicine “Hondra-Force”, the price of which is indicated below, goes on sale in cardboard packs. The ointment is contained in plastic tubes, and the capsules are in cell packages. They are also accompanied by detailed instructions for use.
Pharmacological characteristics
What determines the effectiveness of the Hondra-Force drug? The instruction says that with its therapeutic effect, this medication is obliged to the substances that make up its composition.
Chondroitin is called a high molecular weight mucopolysaccharide, which is found in large quantities in completely different types of connective tissue (including cartilage). It is an additional substrate for the formation of cartilage matrix.
This element inhibits bone resorption and reduces calcium loss. It also affects the phosphorus-calcium metabolism that occurs in the cartilage and bone tissues, accelerates their recovery processes, slows down degeneration, stimulates regeneration and helps restore joint bags and joint surfaces.
It should be noted that chondroitin supports the density of synovial fluid, plays an important role in the lubrication of articular surfaces and prevents the compression of connective tissue. It also inhibits the progression of osteoarthritis, reduces the person’s need for NSAIDs, reduces the severity of pain, normalizes the metabolism in hyaline tissues, stimulates the synthesis of proteoglycans, the formation of hyaluron and collagen of the second type.
Chondroitin in the composition of the drug in question is able to protect hyaluron from enzymatic cleavage (for example, lysosomal enzymes), which is the main cause of the destruction of connective tissues.
Glucosamine properties
What other properties are inherent in the oral Hondra-Force? Capsules, in addition to chondroitin, contain an ingredient such as glucosamine. This is an endogenous substance that is part of glycosaminoglycans and proteoglycans. It is able to activate the synthesis of proteoglycans, chondroitinsulfuric and hyaluronic acids, as well as other elements that are the building material for intraarticular fluid, articular membranes and cartilage.
The presented element enhances the synthesis of cartilage matrix and normalizes the processes of calcium deposition in bone tissue. It also protects cartilage from chemical damage, including those caused by glucocorticoids and NSAIDs.
Glucosamine is able to have a moderate anti-inflammatory effect. Its regular intake inhibits degenerative processes in the joints, paravertebral soft tissues and spine.
Thanks to this element, the drug in question is involved in the biological synthesis of connective tissue, stimulates the regeneration of cartilage and prevents their destruction.
Thus, the Hondra-Force drug, the instruction of which is presented below, has regenerative, anti-inflammatory and analgesic properties. Its use improves joint mobility and reduces the patient's need for NSAIDs, which significantly improves their quality of life.
Pharmacokinetics
When does the Hondra-Force drug begin to act? The instruction reports that a stable therapeutic effect is observed when using the medication for six months.
When taken orally, 90% of the dose is absorbed from the digestive tract. The highest concentration of the drug in the blood is observed after an hour. The bioavailability of the drug is 13% for chondroitin and 25% for glucosamine.
After distribution, the drug is found in the kidneys, liver and articular cartilage. It is excreted in urine and feces.
What kinetic parameters does the external agent “Hondra-Force” (ointment) have? The pharmacokinetics of this form of the drug has not been investigated.
Indications
Capsules and ointment "Hondra-Force", reviews of which are positive, are prescribed for the complex treatment of diseases of the musculoskeletal system, as well as other conditions that are accompanied by degenerative and dystrophic changes in the tissues of the articular cartilage. These include:
- fractures
- secondary and primary osteoarthrosis, periodontopathy and osteoporosis;
- osteochondrosis, shoulder-shoulder periarthritis, patella chondromalacia, spondylosis.
Contraindications
The medication in question is not prescribed for hypersensitivity to any of its substances, phenylketonuria, a tendency to bleeding, severe renal impairment, acute inflammatory processes at the site of application and thrombophlebitis. Also, it is not used for breastfeeding, under the age of 12 years and during pregnancy.
The drug "Hondra-Force": instruction
Capsules "Hondra-Force" is prescribed only inside. Adults and adolescents at the very beginning of treatment are recommended to take 2 capsules twice or four times a day. After 30 days, the dosage can be reduced to 2 capsules once or twice a day.
The clinical effect of taking such a drug is slow. However, it can persist for a long time after the cessation of therapy.
The minimum duration of treatment with this drug is 6 weeks, and the maximum is 2-3 months.
As for the external form of the drug, it should be used three times a day. The ointment is applied to the affected area with a thin layer and rubbed easily until completely absorbed.
The duration of this course is determined individually, depending on the tolerability and effectiveness of therapy (usually 2-3 weeks). If required, the course can be repeated.
The drug "Hondra-Force": price and analogues
You can buy this medication in any pharmacy. Its cost varies between 180-450 rubles (depending on the form of release, the volume of the tube and the number of capsules in the package).
If the drug in question is contraindicated for you, then it can be replaced with one of the following means. These include: “Diclofenac”, “Voltaren”, “Indomethacin”, “Remisid”, “Nemid”, “Ketonal”, “Chondrolon” and so on.
Reviews about the drug
Both ointment "Hondra-Force" and capsules equally well cope with the task. These funds effectively treat diseases of the musculoskeletal system, and also stop the degenerative and dystrophic changes that occur in the tissues of the articular cartilage.
Patients and doctors argue that the medication in question permanently eliminates pain associated with diseases such as shoulder-scapular periarthritis, osteochondrosis, patella chondromalacia and spondylosis. At the same time, he practically has no contraindications and side effects.