The modern world is full of stress and misery. The constant pressure of relatives, leadership, the second half causes mental health sometimes irreparable damage. Our compatriots are afraid to turn to psychiatrists for help, as they are afraid of registration. This practice has not been conducted for a long time, information about patients is strictly confidential and not subject to disclosure. So you can safely consult a psychiatrist for anxiety, fatigue, constant bad mood and decreased performance. The doctor will prescribe a special prescription drug from the group of tranquilizers or antidepressants. There are many such drugs, but one of the most popular and safe is Grandaxin.
Release form and composition
Grandaxinum is produced in Hungary by the pharmaceutical company EGIS in one dosage form: tablets. Each of them contains 50 mg of tofisopam. Auxiliary components: magnesium stearate, stearic acid, microcrystalline cellulose, medical starch, talc. The tablets are round in shape, white, on one side the inscription GRANDAX is engraved, on the other hand the tablet is smooth. The drug is sold in cardboard packaging, each of which has two or six blisters, each with ten tablets.
Indications for use of the drug
Depending on the symptoms, you can use a different dosage of Grandaxinum. Indications for use are as follows:
- increased anxiety;
- depressive states;
- premenstrual syndrome in women and menopause;
- migraine, headache (as a means to restore cerebral circulation);
- apathy, lethargy, asthenia, chronic fatigue;
- trouble sleeping
- withdrawal and hangover syndromes.
Contraindications
Caution should be exercised if the patient has the following problems:
- chronic kidney and liver diseases;
- suicidal tendency;
- drug addiction;
- epilepsy;
- period of pregnancy and lactation;
- chronic respiratory diseases;
- problems with the cardiovascular system.
Even if there are indications for the use of Grandaxin tablets and positive reviews, you should be extremely careful in taking them and slowly increase the dose, starting with the lowest. Self-administration without consulting a doctor can lead to exacerbation of existing problems and cause complication of chronic diseases of internal organs.
Side effects
The following side effects may develop:
- drowsiness, constant desire to lie down (in the first week of taking a tranquilizer);
- slight dizziness, nausea (if these symptoms appear, the dosage should be reduced);
- nervous irritability, irritability (in the first two weeks of admission);
- allergic reactions (skin itching, urticaria, dermatitis).
Indications for the use of Grandaxin tablets justify the development of side effects in the first week of administration. If the expected benefit of taking the drug is more from possible side effects, then you should overcome the first week. After ten days, the body adapts to the action of a tranquilizer, and the manifestations of side effects will come to naught.
Drug interaction
Antihypertensive drugs enhance the sedative effect of "Grandaxinum". Antacid drugs slow down the absorption of "Grandaxinum", as a result of which the patient does not immediately feel its effect. In this case, the risk of overdose is possible (without noticing the effect, people significantly increase the dosage).
Antimycotic drugs increase the concentration of tofisopam in the blood. In parallel with "Itraconazole", "Ketoconazole" should reduce the dosage of "Grandaxinum" in half.
With a parallel intake with alcohol and with therapeutic tinctures for alcohol, it is possible to increase the sedative effect, drowsiness, ethanol coma.
Patient reviews. Reception for anxiety and depressive disorders
The most common indication for the use of the drug "Grandaxin", according to reviews, depression of various origins.
With endogenous depression, Grandaxin is almost not used, since it has a weak effect on neurotransmitters. It can perfectly stop anxiety, psychotic conditions. Often, psychiatrists prescribe this drug in the first weeks of taking antidepressants, in which case Grandaxin serves as a medical cover for the development of side effects and serotonin syndrome.
Indications for the use of "Grandaxin" - anxiety disorders. Reviews of people taking the drug indicate a leveling out of the emotional state. Already on the third or fourth day of admission, anxiety decreases, unpleasant thoughts go out of their head by themselves (according to patients). A light sedative effect helps to establish a healthy sleep, which affects performance and vigor.
Patient reviews on the treatment of psychopathic conditions
Initially, tranquilizers as a class of medications were created specifically for the relief of such conditions. Indications for the use of "Grandaxin" are diverse, but the first place among them is occupied by conditions requiring a sedative effect precisely in psychopathic conditions.
Reviews of patients note that the maximum sedative effect develops on the fifth or sixth day of admission. Significant relief comes, nervousness and emotional tension decrease.
Reviews about the treatment of hangover and withdrawal syndromes
A special place among the indications for the use of "Grandaxinum" is the relief of hangover and withdrawal syndromes. According to those taking it, the drug helped many people avoid alcohol delirium tremens (delirium tremens). This condition develops, as a rule, after three to four days of drunken alcohol consumption. After exiting binge, delirium is formed due to irreversible damage to the central nervous system. The body needs a dream. Indications for use and reviews of "Grandaxinum" confirm that the tablets help the patient fall asleep and thereby avoid delirium.
In addition, the drug helps to stabilize the state during the hangover period: relieves anxiety, has a calming effect. If the patient has tremor of the extremities, a tranquilizer will help reduce it. "Grandaxin" also improves blood circulation in the brain and helps to restore cognitive functions after prolonged binge. Do not self-medicate: if after binge there is an opportunity to go to the hospital of an addiction clinic, then it is better to do this. Reception "Grandaksin" - not a 100% guarantee that delirium tremens will not get its development.
Reviews on taking the drug during premenstrual syndrome
In this difficult period for every woman, the action of the tranquilizer will come in handy. The direct indication for the use of "Grandaxinum" is premenstrual syndrome. The drug effectively relieves anxiety, aggressiveness and irritability during this period.
Women’s reviews of the drug are mostly enthusiastic: they note peace and tranquility after a couple of days of taking the drug in a therapeutic dose. Of the minuses - you need to constantly take a prescription for the drug from a psychiatrist or neuropathologist, since many pharmacies refuse to sell over-the-counter patients. "Grandaxin" refers to a group of tranquilizers, which means that it can be purchased only by prescription.
The drug is also effective for mental disorders during menopause. It effectively reduces dysphoria, mood swings, unmotivated aggressiveness.
Analogs
Indications for use of the drug "Grandaxin" are specific, but there are many analog drugs with the same properties.
- Phenibut is still sold by many pharmacies without a prescription; this is not a tranquilizer, but a nootropic. In action, it is very similar to the “Grandaxin”. Patients who took both of these drugs note their similarity: sound sleep, sedative and anti-anxiety effects. If you take "Phenibut" in the morning, it has a slight stimulating effect. When taken in the evening, on the contrary, it helps to fall asleep faster.
- Afobazole is weaker than Grandaxin. But you won’t need a prescription either: it belongs to the class of drugs that are available for sale.
- The complete analogue of Grandaxin according to the structural formula is Tofisopam. It is difficult to find on sale, it is a domestic medicine and costs about a hundred rubles (three times cheaper than Grandaksin). A completely identical medication. Contraindications, side effects, indications for Grandaksin tablets - all coincide with the instructions for Tofisopam. These drugs are exactly the same.
- "Mexidol" - also has an excellent effect on withdrawal symptoms and anxiety, although it has a completely different structural formula and its principles of action are different from the work of "Grandoxin". Mexidol has an antidepressant effect. However, it establishes a dream and can be effectively used as an anti-anxiety agent.
- "Corvalol" (alcohol tincture or tablets) is not recommended for simultaneous use with "Grandaxinum", but may well replace it as an independent remedy.
- “Cinnarizine” dilates the vessels of the brain and is a nootropic, but in its effect on the patient’s nervous system and well-being it is similar to “Grandaxin”: it has a mild sedative, moderately hypnotic and anti-anxiety effect.
Medical Tips
Indications for the use of "Grandaxinum" make this drug the object of close attention of neurologists and psychiatrists. This tranquilizer takes one of the leading places among sedatives. Here are some tips to make your medication as effective as possible:
- coffee and strong black tea reduce the effectiveness of Grandaxin, caffeine interrupts its sedative effect and overloads the patient’s nervous system;
- you can not combine the intake of tranquilizers and drinking alcohol;
- while taking "Grandaxin" should refrain from extreme sports and potentially life-threatening activities of the patient (due to a delayed reaction);
- concurrent use of "Sirolimus", "Cyclosporine" and "Grandaxin" is contraindicated;
Before use, it is necessary to carefully study the instructions for use and indications, "Grandaxinum" is a serious drug, and self-medication is unacceptable to them. Often prescribed by psychotherapists, neurologists with VSD.