The drug "Grandaxin" refers to pharmacological agents with a tranquilizing and anxiolytic effect. In simple terms, with regular use of Grandaxin, the patient disappears painful anxiety, a sound and healthy sleep is established, and unrest recedes into the background. Against the background of taking the drug, it is easier to survive serious stress, parting or loss of a loved one and other life difficulties and troubles. In patients who take the medicine, the question often arises: is it possible with Grandaxin alcohol and what are the consequences of such mixing?
Composition and form of release
"Grandaxin" is produced by the Hungarian Pharmacological Plant in only one form of release - tablets. The main active ingredient is tofisopam. One tablet contains 50 mg of tofisopam, as well as excipients - magnesium stearate, stearic acid, microcrystalline cellulose, potato starch, talc, lactose monohydrate. One cardboard package contains 2 or 6 blisters, each containing 10 tablets. The cost of the drug varies from 300 to 900 rubles (the price depends on the margin of the pharmacy chain and on the number of tablets in the package).
The difference between Grandaxin and many other tranquilizers is that the drug does not lead to the development of drug dependence. Unlike tranquilizers of the benzodiazepine series, Grandaxin does not cause excessive drowsiness, mental and motor inhibition, does not lead to delayed ejaculation and problems with libido. If the patient, while taking “Grandaxin", notes such problems in himself, then most likely the person is overly impressive. The fact that he takes tranquilizers leads him to hypochondria.
"Grandaxin" promotes mild stimulation of the nervous system, which is perceived by the patient as a good mood and lack of anxiety. Also, patients note that against the background of the reception, the muscles relax, the pain of psychogenic origin disappears. The maximum concentration of tofisopam in the blood is observed two to three hours after taking the pill. The active substance is absorbed in the stomach and partially in the intestine, after which it enters the bloodstream. The remainder of tofisopam is excreted with urine, and about 30% - with feces.
Indications for use of "Grandaxinum"
Instructions for use with the drug reports that the drug can be prescribed as an independent drug or as part of complex therapy for the following disorders and conditions:
- Neurotic and neurosis-like conditions, which are accompanied by anxiety.
- Panic attacks of various origins.
- Problems falling asleep and disturbed sleep phases.
- Increased nervous irritability, hyperactivity, motor anxiety.
- Pain in the heart of psychosomatic origin.
- Withdrawal syndrome in chronic alcoholism.
- Depression with elements of psychopathy (in this case, the drug should be used as part of complex therapy).
- Muscle cramps and nerve tics, the cause of which is excessive nervous tension.
Feasible side effects
Instructions for use with the drug reports that in some cases, the drug provokes the appearance of the following side effects:
- On the part of the nervous system - increased irritability, in the first days of admission there may be problems with sleep, headache, and attention disorder.
- From the digestive organs - diarrhea, bloating.
- Some patients complained of pain in the epigastric region when taken on an empty stomach.
- On the part of the endocrine system: increased appetite and, as a result, weight gain.
Contraindications
Grandaxin should not be taken during pregnancy. Despite the fact that the drug has a very mild effect on other tranquilizers, its effect on the fetus has not yet been adequately studied and theoretically can cause the development of certain pathologies.
Since the drug is absorbed in the stomach and partly in the intestine, subsequently entering the bloodstream, persons with chronic diseases of these organs should be taken with caution. The use of "Grandaxinum" can provoke deterioration in patients with chronic diseases of the liver, stomach and intestines. Doctors usually advise taking the pill after a meal - this can reduce the irritating effect of the drug on the gastric mucosa.
Interaction with other medicines
Taking barbiturates and antiepileptic drugs reduces the concentration of tofisopam in the blood. As a result of this drug combination treatment "Grandaxinum" loses all meaning.
When taken simultaneously with antifungal drugs, the conversion of tofisopam in the liver to active metabolites slows down, as a result of which it is impossible to predict the exact concentration of the substance in the blood. The patient may feel severe drowsiness, or, conversely, experience motor anxiety or even a panic attack.
Grandaxin may increase the concentration of Digoxin in the blood. It is undesirable to combine these drugs.
Special instructions for admission
It is extremely undesirable to take "Grandaxinum" in parallel with the tincture of "Corvalol". The basis of the latter is ethyl alcohol, and combining Grandaxin with alcohol is extremely undesirable.
The drug is often prescribed for simultaneous administration with antidepressants (both tricyclics and from the SSRI group). This practice is quite normal, especially if the person first started taking antidepressants. It should be noted that “Grandaxin” cannot be combined with alcohol while taking antidepressants - there is a high risk of getting serotonin syndrome. The course of treatment with antidepressants should be observed in sobriety.
Grandaxin and alcohol compatibility
In practice, it often happens that patients ask a similar question. Ironically, the drug is often prescribed by psychiatrists and narcologists to people suffering from withdrawal symptoms, that is, chronic alcoholics. It is very difficult for people with alcohol addiction to refuse to take the next dose of alcohol. This raises questions about the compatibility of Grandaxin and alcohol. How long can I drink alcohol after a course of treatment with "Grandaxinum" and what are the consequences while taking it?
It is important to understand that any alcoholic beverage in the composition has ethyl alcohol. This is a fairly toxic substance, but when it is in the blood, a person experiences euphoria, his consciousness changes. For this condition, the person "pays" the subsequent withdrawal symptoms, as well as the appearance of chronic diseases of internal organs. Withdrawal syndrome really becomes less pronounced if you take "Grandaxinum".
You can try to replace alcohol with something in your life. For example, getting euphoria from doing extreme sports, finding a hobby or trying to radically distract (change jobs, social circle, etc.). But the simultaneous use of "Grandaxin" with alcohol is devoid of any meaning. Moreover, such a combination can aggravate the condition of a person with alcohol dependence.
Implications for Internal Organs
What are the consequences of combining Grandaxin and alcohol for internal organs? Of course, the liver is the first to suffer. This body is the first to take the “blow” when ethyl alcohol enters the body, splitting it and contributing to its withdrawal. The more people drank alcohol during treatment with "Grandaxinum", the more the liver suffers. If the patient already has a diagnosis of toxic hepatitis or the presence of hepatosis, then in no case should you mix Grandaxin with alcohol. It is possible to provoke the development of cirrhosis.
The pancreas also suffers. With the simultaneous administration of tranquilizers and alcohol, the production of insulin is disrupted. In a healthy person, this process is not so pronounced, but if pancreatitis is present, then even a single intake of alcohol and Grandaxin can provoke pancreatic necrosis. Reviews of people who, due to their inexperience, drank a large amount of alcohol during treatment, report that the next day they experienced pain in the left side. Most likely, this is an attack of pancreatitis. If the pain is severe, you should consult a doctor as soon as possible or call an ambulance.
Implications for the nervous system and psyche
Ethyl alcohol is a strong depressant. People say that taking a certain dose of a drink relaxes a person, strengthens his nervous system. Any narcologist will confirm that this is just a myth! In fact, alcohol contributes to the death of nerve cells and their subsequent exit from the body.
With regular alcohol abuse, the psyche is depleted. A person becomes nervous, irritable, vulnerable and tearful. As a rule, at this stage, many people are looking for a way out in pharmacology and begin to take "Grandaxinum". But without giving proper attention to the problem of alcoholism, people continue to use both Grandaxin and alcohol.
How much after a course of treatment can I drink alcohol? Optimal - not less than a week later. It should be remembered that drinking alcohol will provoke increased anxiety and the appearance of a depressive state, panic attacks.
Drug and alcohol addiction
As described above, Grandaxin does not cause drug dependence. However, a person with chronic alcohol dependence can get used to the pills. Extinguishing withdrawal symptoms after the fact of abuse is very comfortable.
As a result, a person nevertheless gains an addiction - and double. In narcology, this phenomenon is called polydrug abuse. If, against the background of abuse, a person also took antidepressants, in addition to Grandaxin, then his body and psyche will wear out very quickly. It is very difficult to get rid of polydrug abuse - you need the help of a qualified specialist.
The opinion of doctors about the compatibility of alcohol with the drug
Doctors of various fields of medicine unanimously argue that mixing tranquilizers with alcohol is prohibited. In a drunken state, it is easy to quietly exceed the dosage — and this is already fraught with very serious consequences, even death.
If a person wants to maintain health and a strong psyche, then you can not mix "Grandaxin" and alcohol. How much can I drink after the course of treatment? Of course, it’s optimal not to do this. But if an irresistible desire arises, then not earlier than five to six days after the completion of the course.