The medicine "Papaverine" belongs to the category of vasodilating and myotropic antispasmodics. The bioavailability of the drug is about 54%. The medicine has the ability to quickly bind to plasma proteins. The body is evenly distributed.
At an increased dosage, the drug penetrates the histohematological barrier and affects the patient’s nervous system. The decay process occurs in the cells of the liver. The remedy is excreted by the kidneys.
The composition of the drug contains papaverine and bendazole. The latter has a direct effect on the smooth muscles of blood vessels and organs in the abdominal cavity. In addition, bendazole has the ability to stimulate the activity of the spinal cord. With prolonged use, an immunomodulating effect is manifested, in particular, the production of interferon and the activation of phagocyte activity are enhanced. Papaverine reduces the concentration of calcium in muscle cells. Due to this, the resistance inside the vessels decreases. The result is a decrease in blood pressure. About 50 rubles - such is the price for the drug "Papaverine". Tablets are prescribed to patients from the age of twelve.
Indications
The drug is recommended for spasms of smooth muscles, accompanied by pain. The Papaverine medication is prescribed (tablets, the instructions for use contain such information) at elevated pressure. For patients with angina pectoris, the drug is recommended in combination with other medicines. The medicine is also prescribed for sedation in anesthesiology. Papaverine (tablets) is indicated during pregnancy. In the prenatal period, the medication is prescribed to patients with increased uterine tone. Therapy is carried out under the close supervision of a doctor.
Dosage regimen
The drug "Papaverine" (tablets) instructions for use recommends taking 40-60 mg. Frequency of admission per day - 2-3 times.
Contraindications
No medication is prescribed for neurological disorders, head injury, convulsive syndrome. Contraindications include hypotonic bleeding and a predisposition to them, low blood pressure, bronchial obstruction syndrome. The medicine "Papaverine" (tablets) does not recommend the use of the drug for liver or kidney failure in acute or chronic course, hypertrophic processes in the prostate. The drug is contraindicated in case of intolerance.
Side effects
The tool can provoke dysfunctions of the cardiovascular system, excessive sweating, dizziness. Complications also include a sharp decrease in pressure, arrhythmia, aching pain in the abdomen, constipation, nausea.
additional information
When treating elderly patients, the Papaverine drug (tablets) is recommended for use in a reduced dosage (10 mg). In practice, there have been cases of mutual strengthening or weakening of the therapeutic effect with the combined use of the drug with antispasmodics, tranquilizers, antidepressants. In this regard, if necessary, in a combination of means, dosage adjustment may be required.