In the article we will study the instructions and reviews for “Gelarium”. A medication is a herbal preparation that has an anxiolytic and antidepressant effect.
According to the instructions for use with Gelarium Hypericum, the dosage form of this medication is dragees, which have a round biconvex shape and a greenish-yellow shell. Dragees are packaged in blisters of 15 pieces, placed in a cardboard package of 2 blisters. In addition, a cardboard pack can contain 3 blisters with 20 tablets or 2 blisters with 25 tablets.
Structure
In 1 tablet of the medicinal product contains the main active substances - extract of St. John's wort perforated (grass) and 60% ethanol. The following components are used as auxiliary components in the production of this medicine: colloidal silicon dioxide, lactose, potato starch, magnesium stearate.
The shell contains shellac, sucrose, kaolin, macrogol, calcium carbonate, titanium dioxide, gum arabic, yellow quinoline, talc, a green lacquer.
Indications for appointment
As the instructions indicate, "Gelarium Hypericum" is used for the following pathological disorders:
- neurotic reactions;
- mental and autonomic disorders, including decreased mood, apathy;
- mild and moderate severity of depressive disorders.
Are there any restrictions on the reception of funds?
Contraindications
The medication is contraindicated in such cases:
- patient age less than 12 years;
- insufficiency of lactase, isomaltase or sucrase, lactase intolerance, glucose-galactose malabsorption;
- photosensitization (sensitivity) of the skin to ultraviolet radiation;
- combination therapy with tacrolimus, cyclosporine (for systemic use), HIV protease inhibitors (including indinavir, amprenavir), warfarin, monoamine oxidase inhibitors, irinotecan;
- period of pregnancy and lactation;
- intolerance to components.
Instruction manual
"Gelarium Hypericum" is taken orally during meals, in whole, with water. Recommended dosing regimen: 1 tablet 3 times a day, the duration of treatment - from 28 days (at the discretion of the attending physician). If clinical symptoms persist after 28 days of taking the medicine, you need to get further specialist advice.
Side effects
In accordance with the instructions for use and reviews, Gelarium Hypericum can provoke the following negative reactions:
- CNS: excessive fatigue, headache, anxiety.
- Digestive system: dry mouth, flatulence, nausea, abdominal pain (including the epigastric region), diarrhea, anorexia, constipation.
- Allergic reactions: skin pigmentation, itchy skin, rash, eczema, increased sensitivity to animal hair particles, photosensitivity.
- Hematopoietic organs: anemia of iron deficiency type.
If such negative symptoms occur, you should immediately consult a doctor.
Special recommendations
What else does the instruction manual for Gelarium Hypericum tell us? In one tablet there is less than 0.03 XE. This allows you to take this medication to patients with diabetes. The combined use of ethanol-containing medicines and the use of alcohol are contraindicated.
During the treatment period and within 2 weeks after it, it is recommended to avoid prolonged exposure to the skin of direct sunlight, visits to the solarium, and the use of ultraviolet lamps. The time interval between taking dragees and MAO inhibitors should be at least 2 weeks. An adverse reaction in the form of photosensitization is most often observed in HIV-infected patients.
The impact of the drug in no way affects the person’s ability to drive vehicles and complex mechanisms.
Drug interaction
With the concomitant use of the pharmacological preparation Gelarium according to the instructions with indirect anticoagulants (warfarin, fenprocoumon), digoxin, midazolam, cytostatics (including imatinib), fexofenadine, amitriptyline, theophylline, methadone, benzodiazepin, medication, nortriptyme, medication, nortriptyme, finistriptyne, nortriptyme, medication .
Such substances as nefazodone, buspirone, sertraline, antidepressants (triptans) can enhance their therapeutic effect and provoke the appearance of vomiting, nausea, confusion, severe anxiety, and fear.
Thiazide diuretics, sulfonamides, tetracycline, piroxicam, quinolones enhance the photosensitizing effect.
General anesthesia medicines, as well as some narcotic analgesic drugs increase their effect on the patient's body, causing a longer sleep.
With the simultaneous administration of reserpine, its hypotensive effect is reduced. When combined with cyclosporine, indinavir, digoxin, their concentration in the blood and therapeutic effects are reduced. When using ethinyl estradiol and desogestrel, the likelihood of breakthrough bleeding increases. During therapy with theophylline, the metabolic rate of the drug “Gelarium Hypericum” increases.
During combined use with oral contraceptives, their contraceptive properties are reduced, which requires the use of additional contraceptive methods. Hypericum perforatum reduces the period of sleep caused by barbiturates.
Analogs
Analogs of “Gelarium Hypericum”, which can be found on the domestic pharmacological market, are:
- "Deprim" is a phytopreparation made on the basis of St. John's wort extracts and has anxiolytic and antidepressant properties. The main substance of this medicine contains flavonoids, hypericin, pseudohypericin, hyperforin, which normalize the functional state of the main and autonomic nervous systems. A similar analogue of “Gelarium” in composition increases mood and helps to strengthen physical and mental activity.
- Rexetin is a synthetic drug based on the substance paroxetine. It is an antidepressant that inhibits neuronal reuptake of serotonin in the structures of the central nervous system. The neuronal uptake of substances such as norepinephrine and dopamine, virtually no effect. Also, this medication has anxiolytic and psychostimulating effects. It is used for depression of various origins, conditions accompanied by anxiety, obsessive-compulsive pathologies (obsessive syndrome), post-traumatic stress disorders, panic attacks, including those that occur with agoraphobia (fear of being in the crowd), and generalized anxiety disorders and sociophobia. What other analogues of “Gelarium Hypericum” are on sale?
- Cipralex is an escitalopram-based medication that is a selective serotonin uptake inhibitor and antidepressant with significant affinity for the primary binding site. The substance reacts with the allosteric site of formation of the transporter protein, the allosteric modulation of which increases the level of escitalopram binding in the primary region, which leads to a stronger inhibition of serotonin uptake. A similar medicine is prescribed for social anxiety disorders, obsessive-compulsive disorders, depressive episodes of any severity, generalized anxiety and panic disorders.
- "Fluoxetine" is a drug that refers to propylamine derivatives. The principle of its effect is due to the selective ability to suppress the uptake of serotonin in the central nervous system. In this case, the medication has a minimal effect on the exchange of acetylcholine, dopamine and norepinephrine. Such a medical tool reduces the feeling of tension and fear, eliminates anxiety, and improves mood. It does not cause orthostatic pressure reduction, does not affect the myocardium. “Fluoxetine” is indicated in the treatment of depressive and obsessive states of varying severity, in case of anorexia (bulimia, anorexia), as well as in the complex treatment of alcoholism.
Reviews
Regarding the use of Gelarium Hypericum, there are various reviews - both good and bad. Patients note that the herbal remedy has pronounced effectiveness in the treatment of a variety of anxiety and depressive disorders. It quickly eliminates the feeling of panic, fear, improves mood and helps get rid of numerous nervous and vegetative disorders.
Among the negative reviews from patients are those that contain information about the development of adverse reactions from taking this medication. People indicate that taking this drug is not very convenient, due to the fact that it interacts poorly with other medications that are sometimes necessary for patients to treat concomitant diseases. Among the side effects, the most frequently observed phenomena are dyspepsia, dizziness, and stool disorders. We reviewed the instructions and reviews for "Gelarium Hypericum."