Among the huge number of drugs that are presented on the Russian market, it is difficult to find funds that do not cause side effects. Despite the achievements of modern pharmaceuticals, almost all drugs, even with the correct intake and dosage, can cause some harm to the patient's body. However, it is impossible to do without medications at all, because for a number of diseases it is necessary to carry out therapy as quickly as possible.
The list of such problems is quite wide, and diseases of the stomach and duodenum occupy not the last place in it. When making such diagnoses, the doctor usually prescribes a course of treatment with De-Nol. This drug is considered one of the most effective and safe. Of course, this statement is true only if all medical recommendations issued simultaneously with the appointment are followed. However, most patients still have many questions regarding this drug. How many days does De-Nol treatment last with a stomach ulcer? How to take pills? How often to repeat the course "De Nola"? Are side effects normal during treatment? What is the best De-Nola course for gastritis?
Judging by the above questions, most often patients try to find out details about the duration of treatment. This is the topic we will touch on in the article. Readers will draw from it all the information they are interested in about the De-Nol treatment course. We will also briefly give a description of the drug itself and note all the features of its administration.
General characteristics of the drug
As soon as the doctor after the treatment has diagnosed the patient with an “ulcer” or “gastritis”, he will most likely prescribe him a De-Nol treatment course. How often to drink pills and how to do it, the doctor usually tells right there in the office, but he does not give a description of the medicine. Although this information is very useful for patients.
So, first of all, it is worthwhile to understand that this drug is one of the most powerful. In addition, it allows you to comprehensively approach the problem, and this already makes it possible to prescribe a simplified scheme and course of treatment. “De-Nol” and “Omez” confuse many patients with each other, considering them to be equivalent drugs and replacing them of their own free will. However, this cannot be done, since the tool we are describing is unique in many respects.
How many days the course of treatment "De-Nol" lasts with gastritis and ulcers, we will tell a little later. Now find out what kind of drug. The medication has both healing and antiseptic properties, which makes it indispensable in the treatment of diseases of the gastrointestinal tract. It also has astringent properties that help the drug more effectively cope with diseases. In addition, the course of treatment "De-Nol" relieves the patient of Helicobacter pylori, which is the culprit in the occurrence of peptic ulcer. A huge plus of the drug is the fact that it does not apply to antibiotics. And therefore, it will not cause serious side effects inherent in this group of drugs.
I would like to mention that even with a long course of taking "De-Nol", Helicobacter pylori cannot develop resistance to the drug. The medication is equally effective in primary and secondary treatment. Similar characteristics are rarely combined in one drug.
Product release form
Before starting a course of treatment with De-Nol for gastritis or peptic ulcer, it is necessary to protect yourself from fakes. This requires studying how the tablets should look.
The manufacturer releases the drug only in the form of tablets. They have a biconvex shape and are covered with a film membrane. Typically, the color of the tablets is close to light cream, but slight deviations towards a darker or lighter shade are also allowed.
Pills are very well protected from fakes due to embossing. It is applied on both sides and consists of an inscription and a graphic drawing. Some patients treated with De-Nol have complained of the unpleasant odor emanating from the pills. Pharmacists point out that this is the norm. Original tablets may not emit a very pronounced smell of ammonia.
The manufacturer packs the drug in cardboard boxes. Each contains several blisters. They are placed on eight tablets. On average, from seven to fourteen blisters are invested in a pack. The maximum number of tablets per pack is one hundred and twelve.
Depending on the neglect and nature of the course of the disease, the doctor may prescribe both the minimum course of treatment with De-Nol and the maximum with a possible repeat in a few months. Based on this, the patient has the opportunity to pre-calculate which package of tablets he will need.
The composition of the drug and dosage
Often, patients with peptic ulcer and gastritis try to independently compare between themselves De-Nol and Omez. The treatment regimens and the course of taking these medicines, however, vary widely. And this is not surprising, because despite the fact that the preparations have similar indications for use, they contain various active ingredients.
"De Nol" consists of active and additional substances. The first category includes bismuth oxide. It is this substance that provides the wide therapeutic effect that the drug has. Its in each tablet is 120 milligrams.
Auxiliary components are selected and included in the composition of the drug in order to contribute to the rapid absorption of the active substance in the gastrointestinal tract. This group of components includes:
- corn starch;
- povidone;
- magnesium stearate;
- potassium polyacrylate.
In addition, it is necessary to mention the components that make up the film coating of tablets:
All excipients are in small quantities in the drug.
Indications for taking pills
In almost a hundred percent of cases, the doctor prescribes a course of treatment with De-Nol for stomach ulcers and gastritis. However, these are not the only indications for taking this drug. The list of health problems that tablets effectively cope with is quite extensive:
- peptic ulcer of the duodenum at different stages of the course;
- gastroduodenitis;
- irritable bowel syndrome (including with diarrhea as one of the symptoms);
- dyspepsia;
- peptic ulcer of the stomach;
- peptic ulcer of the duodenum;
- lesions of the gastric mucosa.
Most often, the last of these problems occurs with prolonged use of non-steroidal anti-inflammatory drugs.
Drug action
The range of action of the tablets is wide enough, therefore, with peptic ulcer and gastritis, the course of treatment "De-Nol" is so effective. Even after the initial intake, the drug forms a protective film that envelops the inner walls of the stomach. Moreover, it very effectively neutralizes Helicobacter pylori.
In parallel, the drug helps to normalize the acid-base balance, improve blood circulation in the stomach, accelerate metabolic processes. It is also noted that during the treatment, the rate of regeneration of damaged tissues increases.
Doctors say that even the damaged mucous membrane of the stomach is actively destroyed by the pepsin produced by the body. Its concentration decreases significantly after a course of treatment with De-Nol (and Omez, by the way, a similar effect can be achieved).
We can not fail to mention the fact that the drug acts as a means to strengthen the immune system. It is proved that a decrease in its activity creates all the conditions for the penetration of Helicobacter pylori into the body. The more immunity is reduced, the more harmful bacteria penetrate. Initially, it manifests itself as a symptomatology of gastritis, then it becomes the cause of ulcers on the mucous membrane. And at this stage it can already threaten the patient with oncology.
The mechanism of action of tablets on the causative agent of peptic ulcer
Readers have already learned from our article what De Nol cures. The course of treatment with this drug successfully neutralizes Helicobacter pylori.
The mechanism of action of the drug on this harmful microorganism is quite simple. When taking the drug, the effect is directly on the cell walls of the bacterium. They begin to collapse, and as a result of this process, irreversible changes in the cytoplasm of the microorganism occur. After a while, he dies.
It is noteworthy that the active substance of the drug is able to penetrate into the deepest tissues and restore them. The moment of lack of addiction to the tablets is very important even with prolonged use. Helicobacter bacteria can not adapt to the components of the drug, so it is effective when repeated.
Contraindications
Do not forget that not all patients “De-Nol” is suitable, despite its high performance. Some health problems can be an obstacle to taking it. However, their list is limited to only a few points:
- Reception of other funds containing bismuth. This substance has the ability to accumulate in the body, so there should be a break between therapeutic courses at least three to four months.
- Childhood. Typically, a child under fourteen years old is not prescribed De-Nol. But there are exceptions to this rule: in especially difficult cases, the doctor may prescribe this medicine to a baby from four years old. This can be done as part of complex therapy in conjunction with two antibiotics. Moreover, the course of treatment with De-Nol (such situations are not specified in the instructions for use) should be minimal.
- Pregnancy and lactation. Women expecting a baby should avoid taking this drug. Its active substance has a negative effect on the fetus, as a result, a child can be born with serious pathologies. During lactation, De-Nol is also contraindicated. Its components penetrate into breast milk very easily and disrupt the functioning of the urinary and nervous systems of the baby. The result of such treatment for the mother can be very disastrous for the baby.
- An allergic reaction to bismuth is rare, but it can still be. Therefore, people prone to allergies, De-Nol is not worth drinking. Doctors do not prescribe it and with individual intolerance to any components of the drug.
- The drug is categorically contraindicated in diseases of the kidneys of a different nature and severity.
The instructions for the tablets noted that they should not be taken to people with problems associated with liver diseases. In these cases, treatment can aggravate them and be supplemented by a number of side effects.
The drug is "De-Nol." What treatment is considered optimal
The attending physician prescribes the drug to people suffering from diseases of the digestive tract. Moreover, they definitely must be over fourteen years old. The doctor only makes up the intake schedule; doing this without authorization is strictly contraindicated. The specialist takes into account all the nuances of the course of the disease: its stage, severity, age of the patient and the like.
On average, no more than four tablets of the drug are prescribed per day. Moreover, they should be taken at regular intervals. Depending on the treatment regimen, the doctor may divide the daily dosage into two or four doses.
The standard course of treatment involves a regimen in which the patient drinks one tablet four times a day. The first three receptions occur before breakfast, lunch and dinner, and the last - at night. It is important to drink the pills thirty minutes before meals on a completely empty stomach. This concept includes not only the lack of food in it, but also fluid.
An alternative course of treatment is prescribed for other diseases. In this case, it is shown to take "De-Nol" two tablets twice a day - before breakfast and dinner. It is important to observe an interval of twelve hours between doses.
The drug needs to be washed down with pure water only. Juices, teas and other drinks, reacting with the components of the drug, violate the absorption of the drug and its mechanism of action.
It should be borne in mind that tablets can not be chewed, broken or taken in parts.
The minimum course of therapy is one month, but often doctors advise, with obvious improvements in the condition, accompanied by the neutralization of unpleasant symptoms, to stop treatment.
The longest course of "De Nola" can not be more than two months of continuous use. If stabilization of the state has not occurred during this period of time, then the next time you can start drinking the medicine only after a sixty-day interval
It should be borne in mind that the patient can not take other drugs containing bismuth in their composition. This substance gives the effect of accumulation in the central nervous system, which negatively affects its work.
Treatment features
"De-Nol" is a fairly powerful drug, so when you take it, you must follow some simple rules.
Patients should know that the drug is most effective when thirty minutes before the tablet enters the body and thirty minutes after this, food and liquid do not enter the stomach. The fact is that a large amount of gastric juice is required to break down the tablets.
In case of vegetovascular dystonia, it is necessary to undergo the most minimal course of taking De-Nola. If this recommendation is not followed, the patient's condition will worsen due to regular headaches and dizziness.
Keep in mind that bismuth, which is an active component of the drug, gives an effect such as staining stool in black light. Despite the fact that this reaction is natural, it is necessary to inform the attending physician about it.
If you notice a general deterioration in your condition in the first week of treatment, then it is possible that the side effects of the drug have manifested, which means that the course of treatment should be stopped.
A few words about side effects
If you analyze all the possible negative reactions of the body to taking pills, then most often they occur from the gastrointestinal tract. The main symptoms are nausea, vomiting, violation of the daily stool (constipation, diarrhea, rapid bowel movements, and so on). Flatulence accompanying the patient throughout the day is also possible. In some cases, there is a decrease in appetite and a change in taste preferences. Sometimes in the course of treatment there is a steady smack of metal in the oral cavity. The color of the tongue in many patients changes to dark brown after the first days of taking the tablets. All of these reactions are considered symptoms of the body's adaptation to bismuth. They usually go away in one to two weeks on their own.
Allergies are a good reason to stop treatment. This effect is manifested by skin itching, rashes on the skin and swelling of the tissues. Such symptoms should be reported to the doctor. After examining the patient, he must decide to cancel or change the treatment regimen.
A long course of treatment is possible only under the supervision of a doctor. It is prescribed in very rare cases, since the risk of side effects increases several times. In addition, many of them are hazardous to health. Such reactions include nephropathy, encephalopathy, gingivitis and so on. Often, long-term use of "De-Nola" is the reason for the development of colitis and arthralgia in patients.
Overdose. How to determine it
Starting to take "De-Nol", it is important to understand that an overdose is extremely dangerous for them. It causes irreversible changes in the body. Among them, acute renal failure can be distinguished, which in parallel leads to high slagging and increased pressure.
The most dangerous disorders of the brain. Initially, the patient feels only weakness, then insomnia is added to it. If the drug is not stopped, then treatment can be fatal.
Disorders of the gastrointestinal tract, which turned into a chronic form, are also one of the results of an overdose of De-Nol.
It should be borne in mind that an overdose of the drug occurs with indicators such as one hundred milligrams of bismuth per liter of blood. This can only be determined by laboratory means.
Patients need to know that an antidote to bismuth does not exist.Therefore, doctors use gastric lavage and adsorbents as emergency assistance in case of an overdose. In severe cases, urgent hemodialysis is required.