"Rinzasip" is indicated for use by patients for the treatment of acute respiratory diseases. They are usually accompanied by a sensation of aches in the joints and bones, headache, fever, intoxication, runny nose.
Composition and formulations of the drug
According to the instructions for use, Rinzasip is produced by the manufacturer in the form of a powder, which should be used to make the solution. The resulting solution is taken orally. The powder has an orange color with white spots or light orange. The taste can be currant, lemon, orange. The smell has a corresponding.
Let us consider in more detail what is in the Rinzasip? Each dose of the drug contains the following active components:
- Phenylephrine hydrochloride in an amount of 10 mg.
- Caffeine - 30 g.
- Pheniramine maleate in an amount of 20 mg.
- Paracetamol - 750 mg.
Auxiliary components are: flavorings, sodium citrate, sucrose, anhydrous citric acid, karmuazin, sodium saccharin.
A medicine is packaged in a paper sachet, each of which holds 5 grams. In a cardboard pack can be 5, 10, 25, 50, 100 sachets. Each package is accompanied by instructions for use.
Pharmacokinetics and pharmacodynamics of this drug
As indicated by the instructions for use with Rinzasip, its therapeutic effect is due to the combined effect of its active components.
- Paracetamol is a representative of PNVS. Under its influence, the cyclooxygenase enzyme, which is responsible for the production of prostaglandin by the immune system cells, the main mediator of inflammation, is blocked .
- Caffeine is able to stimulate the brain, which improves well-being and performance.
- Phenylephrine is able to stimulate vascular alpha receptors. As a result, they narrow, the severity of swelling of the mucous membranes in the nose decreases.
- Pheniramine has the ability to block histamine receptors, reducing the severity of the manifestations of allergies that accompany respiratory disease.
All active components of the drug are absorbed into the general bloodstream quite quickly and almost completely. They are metabolized to inactive metabolites mainly in the liver. Excretion is carried out with urine.
Next, we find out in which cases this remedy is prescribed.
Indications for use of the medication and contraindications for use
A solution made from Rinzasip powder should be used to reduce the severity of symptoms associated with respiratory diseases such as nasal congestion, rhinitis, body aches, fever, headache.
There are contraindications for Rinzasip:
- Individual susceptibility to any component that is part of the drug.
- Age to 15 years.
- "Rinzasip" is prohibited during pregnancy, as well as during lactation.
- Parallel therapy with drugs related to MAO inhibitors, tricyclic antidepressants, beta-blockers.
- Simultaneous therapy with drugs that have the same components.
Caution should be exercised when prescribing a medication to patients who are diagnosed with coronary artery atherosclerosis, high blood pressure, diabetes mellitus, thyrotoxicosis, bronchial asthma, chronic obstructive pulmonary pathology, glucose-6-phosphate dehydrogenase deficiency, systemic blood diseases, liver pathologies, Gilbert syndrome .
Before starting therapy with the specified drug, it is extremely important to exclude the presence of each of the contraindications described.
The use of a drug
It is important to follow the instructions for the tool.
Before using the Rinzasip preparation, the contents of the sachet should be dissolved with hot water in the amount of one glass. To completely dissolve the powder components, mix the medicine with a spoon. It is allowed to add honey or sugar to the solution. Children from 15 years old are shown four times the use of the drug for 1 sachet. The drug should be taken at regular intervals. The maximum amount of the drug that can be taken during the day is 4 bags. The average duration of therapy should be 3 days. If necessary, the course can be extended up to 5 days, but no more.
This is confirmed by the instructions for use with Rinzasip.
Negative effects of taking the drug
Against the background of the use of the medication, a variety of negative reactions can develop, such as:
- Allergic manifestations in the form of anaphylactic shock (a reaction accompanied by a critical decrease in blood pressure), bronchial obstruction (narrowing of the bronchi causing respiratory failure), angioedema (characterized by severe swelling of the soft tissues of the face, genitals), urticaria, itching, rash on the skin.
- Papillary necrosis, urinary retention on the part of the excretory system.
- Pancytopenia, anemia, agranulocytosis, thrombocytopenia from the bone marrow, blood system.
- Increased intraocular pressure, mydriasis (dilated pupils) from the visual system.
- Increased irritability, sleep disturbance, dizziness from the side of the National Assembly.
- Increased heart rate (tachycardia), increased blood pressure (arterial hypertension) from the cardiovascular system.
- Functional disorders of the liver, periodic nausea, dry mucous membranes in the oral cavity, pain in the gastric projection from the gastrointestinal tract.
If any of the described negative manifestations occurs, the drug should be stopped. In the future, you should contact a specialist.
What else does the instruction manual for Rinzasip tell us?
Special instructions for the use of a medication
Before starting drug therapy, it is important to fully study the instructions for use, which contains certain specific instructions that must be followed in order to avoid the development of negative reactions:
- When using a medical product, it is important to exercise caution when performing work associated with increased concentration and requiring a fast reaction rate.
- If the therapeutic effect of taking the drug does not develop within 3-5 days, it is important to consult a doctor.
- If it is necessary to use drugs included in other pharmacological groups in parallel, it is important to consult a doctor in advance and exclude the possibility of their interaction with Rinzasip components.
- It is unacceptable to take medications that are derivatives of paracetamol in parallel.
- Throughout the course of therapy should not take alcohol, sleeping pills, antidepressants.
In drugstores, the drug is dispensed freely, that is, a prescription is not required for its purchase. If in doubt about the use of Rinzasip, you should consult with a specialist.
Overdose
The development of symptoms of an overdose of “Rinzasip” from a cold is caused by paracetamol, which is the main active ingredient in the medication. An overdose occurs if the patient simultaneously takes more than 15 grams of paracetamol (each sachet contains 0.75 grams). This phenomenon manifests itself in the following symptoms:
- Lack of appetite.
- Nausea.
- Pallor of the skin.
- Vomiting
- Liver failure.
If this symptom is detected, the patient should rinse the stomach, ensure the intake of activated carbon or other enterosorbents, and introduce an antidote (N-acetylcysteine or methionine). The choice of antidote is carried out by the doctor and depends on the period that has passed since the onset of the overdose.
Analogs of Rinzasip
If necessary, "Rinzasip" can be replaced by one of the following pharmacological analogues:
- "Efferalgan C";
- Khayrumat;
- Fervex;
- "Upsarin UPSA";
- “Teraflu”;
- Stopgripan Forte;
- Rinicold;
- "Revalgin";
- "Piralgin";
- "Paracetamol";
- "Naklofen Duo";
- MIG 400;
- Coldrex
- Ketonal;
- "Influte";
- "Ibuklin";
- "FluFlu";
- "Hydrovit Forte";
- "Voltaren Acti";
- "Brustan";
- "Aspirin complex";
- "Antigrippin";
- "Aquacitramone";
- Advil;
- "Flucoldex N";
- “Febritset”;
- TeraFlu Extra;
- Streamol Plus;
- Spazgan
- Rinza
- "Prostudox";
- Pentabufen;
- "Nalgesin";
- "Naklofen";
- Maksikold;
- Kaffetin Cold;
- Ibuprofen
- "Girel";
- "Hydrovit";
- Brufen
- "Took";
- "Aspirin";
- "AntiFlu Kids";
- AnviMax.
Structural analogues are: “Rinikold HotMix”, “Rinzasip S”, children's “Rinzasip”.
Each of these medications will effectively stop the manifestations of colds, such as chills and fever.
If there is a need to replace Rinzasip with any of its analogues, it is necessary to consult a doctor who will determine the feasibility of such a replacement.
The cost of the drug in pharmacies
The average cost of Rinzasip depends on the region of distribution, the pricing policy of the pharmacy chain that distributes it, and the number of sachets per pack.
So, a package containing 5 sachets will cost about 140 rubles, 10 sachets - 240 rubles.
Patient Reviews About This Drug
There are quite a lot of reviews about the use of Rinzasip. Most of them are positive. The medication has proven its own effectiveness, its cost is affordable. Patients report that negative effects on the background of the use of the drug develop very rarely, and health improves in a short period of time.
The negative side of the drug, patients consider the impossibility of its use for the treatment of patients under 15 years of age, pregnant women; women in the lactation period. Despite contraindications, Rinzasip during a cold really helps relieve the acute symptoms of the disease, lowers the temperature, and improves well-being.
Responses of doctors about "Rinzasip"
Doctors respond positively about this drug. But it must be remembered that Rinzasip is a medicine intended for symptomatic therapy; it does not eliminate the cause of the disease. In this regard, it is important to consult a specialist before using it, who will most likely recommend using it as part of complex therapy.