"Indomethacin", manufactured by Altpharm LLC, is one of the most common potent anti-inflammatory drugs from the group of non-steroidal drugs. In the pharmacy you can find ointments, tablets, solutions and drops, however, the most popular are candles. Experts believe that this tool helps to quickly cure pathologies associated with inflammatory processes, while also providing an analgesic and antipyretic effect.
How it works
After the introduction of the rectal suppository "Indomethacin-Altpharm" into the anus, they melt under the influence of human body heat. As it dissolves, the main component begins to exhibit healing properties, penetrating the intestinal wall. The drug has several effects simultaneously:
- anti-inflammatory;
- antipyretic;
- decongestant;
- painkiller.
The product immediately enters the bloodstream. After absorption by the body, it inhibits the production of the hormone prostaglandin. It is he who is responsible for the rapid development of pain and inflammation. With regular use, Indomethacin-Altpharm suppositories help to suppress all chronic pathological processes, while relieving stiffness and pain. A week after the start of use, you can notice a significant improvement in well-being.
The main active component of suppositories - indomethacin, reaches its highest concentration 1-2 hours after entering the bloodstream. It is worth noting that it is best not to eat any food during this period, since in this case the effectiveness of the medicine will be higher. "Indomethacin-Altpharm" has a very high level of absorption. After the end of the action, it is excreted through the gastrointestinal tract or kidneys, however, due to rapid adsorption, it can often enter the placenta or breast milk.
Composition and form of release
Indometacin altpharm is widely used in many fields of medicine. It is available in various forms, but suppositories have the greatest positive effect when taking temperature, swelling and inflammation. They are used for rectal administration (into the rectum), but in some cases, gynecologists prescribe them to women for use in the vagina.
Each carton pack of this medicine contains 5 or 10 candles. They have a white or slightly yellowish color. The main component of the drug is indomethacin. Additionally, Indomethacin-Altpharm includes paraffin wax, fat and corn starch.
Therapeutic effect
As mentioned above, the drug has anti-inflammatory, analgesic and antipyretic effects. The main active ingredient copes with pain in many diseases of the musculoskeletal system. The anti-inflammatory effect is observed already on the fifth day of treatment. In addition, “Indomethacin Altfarm” helps to cope with joint swelling, morning stiffness and greatly facilitates movement.
Indications for use
Indomethacin suppositories are often prescribed not only by therapists, but also by gynecologists to cure a number of inflammatory diseases. As with complex treatment, and as the main means, they are used for therapy:
- myalgia, gout, thrombophlebitis;
- inflammation in the bone tissue;
- rheumatism, arthritis, osteoporosis;
- infectious diseases in ENT diseases;
- hemorrhoids and prostatitis in men;
- disorders in the body of protein metabolism;
- neuralgia.
According to the instructions for use, suppositories "Indomethacin" in gynecology is prescribed vaginally. The schedule of administration completely depends on the recommendations of the attending physician. Often, the drug is used to relieve a painful condition during menstruation, severe inflammation, with endometriosis or cystitis. For the treatment of complex pathologies, complex treatment is used, one of the components of which is an antibiotic, and the other is indomethacin suppositories. Combination therapy helps with such pathologies:
- ovarian cysts;
- uterine fibroids;
- inflammation of the appendages.
In some cases, suppositories help to cope with situations in which there is a threat of miscarriage.
How to use
Most often, doctors prescribe rectal suppositories (insertion into the rectum). Before using the drug, you should cleanse the intestines. Then you need to wash your hands and enter "Indomethacin-Altpharm" as deep as possible into the anus. For convenience, you can lie on one side or sit down. After the procedure, you need to try not to go to the toilet for an hour, so that the medicine has time to absorb and begin to act. In addition, it is recommended to lie down a few minutes after the manipulation.
Most often, adults are prescribed one candle 50 mg from one to three times a day. It is not recommended to use more than 200 mg per day. If the treatment lasts long enough, then the daily dosage should be no more than 75 mg. Apply "Indomethacin" can only be from 14 years old. The necessary dosage and duration of the course can only be selected by a doctor.
Lactation and pregnancy
It is worth knowing that a medicine can have a negative effect on the fetus. Therefore, "Indomethacin-Altpharm" during pregnancy and lactating women are not prescribed. If it is necessary to use the drug, breastfeeding should be discontinued.
Contraindications
The medicine is not recommended for use with the following pathologies:
- individual intolerance to the substances that make up the composition;
- gastric bleeding;
- gastric and duodenal ulcer;
- bronchial asthma;
- cirrhosis of the liver;
- congenital heart disease;
- kidney disease
- arterial hypertension;
- heart failure;
- hemorrhoids.
With extreme caution, candles should be used for diseases such as hyperbilirubinemia, epilepsy, depression, a tendency to form blood clots. Take "Indomethacin-Altpharm" in old age also relies on the careful supervision of a doctor.
Experts recommend during the period of treatment with the drug to monitor the work of the kidneys and liver, as well as to monitor the peripheral picture of the blood condition. In addition, it is best to refrain from driving vehicles and abandon jobs where a quick psychomotor reaction and special attention are required.
Interaction with other drugs
You should also consider such nuances:
- With the simultaneous use of "Indomethacin" with uricosuric, diuretic and antihypertensive drugs, this drug reduces their effectiveness.
- Combination with paracetamol can cause kidney disease.
- Colchicine, ethanol, as well as the use of non-steroidal drugs increase the risk of gastric bleeding.
- "Indomethacin" increases the effect of fibronolytics, anticoagulants and antiplatelet agents.
- Candles increase the concentration of lithium in the blood.
Side effects
When treated with this drug, the following side effects may occur:
- Digestive system: vomiting and nausea, diarrhea, constipation, bleeding, bloating, the development of hepatitis and jaundice, pain in the abdomen.
- Nervous system: headaches, lethargy and weakness, cramps, depression, involuntary muscle reaction, mental disorders.
- Cardiovascular system: palpitations, jumps in blood pressure, heart failure, compression in the heart.
- Circulatory system: the development of anemia, leukopenia, DIC.
- Sense organs: eye pain, visual impairment, hearing problems.
- Urinary system: nephrotic syndrome, renal dysfunction, nephritis.
- Metabolism: glucosuria, hyperglycemia, hyperkalemia.
- Skin: swelling, itching, swelling, rashes.
The drug may cause allergic reactions. With rectal use, worsening colitis and irritation of the rectal mucosa can be observed. In rare cases, there is swelling of the mammary glands, vaginal bleeding and excessive sweating.
Overdose
If the recommended amount of the drug is exceeded, the following symptoms may appear:
- headaches;
- nausea and vomiting;
- cramps
- memory loss;
- numbness of the legs and arms.
In this case, you must immediately stop using candles and take symptomatic therapy.
special instructions
The instructions for use prescribe precautions and additional recommendations:
- Use candles with extreme caution, since the main active ingredient can cause allergic reactions and side effects.
- After the introduction of the suppository, discomfort in the rectum may appear. These symptoms do not require discontinuation of treatment and are not problematic.
- One of the side effects of the medicine is dizziness, so experts do not recommend performing work that requires an increased level of concentration and driving a car during treatment.
- As a result of their anti-inflammatory effect, suppositories can mask the symptoms of active pathology, therefore, the presence of a bacterial infection with its appointment should be excluded.
In addition, according to the instructions for the use of Indomethacin suppositories in gynecology, it is indicated that women taking the drug in their reproductive age have a risk of suppressing the possibility of becoming pregnant.
Terms and conditions of storage
Indomethacin should be kept in a cool and dry place out of the reach of children. Shelf life is two years from the date of manufacture. The drug is dispensed only with a doctor’s prescription. In free circulation candles are not for sale.
"Indomethacin-Altpharm": reviews
The opinion of patients about this drug is quite controversial.
There are many reviews that speak of the high efficiency of suppositories, the rapid elimination of pain and inflammatory processes.
But at the same time, opinions indicate the manifestation of serious side effects, allergic reactions, burning, itching and worsening of well-being.