Pomalidomide is a drug that belongs to a new generation of antitumor immunomodulators. This substance has the ability to inhibit stromal (stem) cells, which support the development and growth of myeloma. In addition, it causes apoptosis (programmed death of defective cells) and inhibits proliferation (tissue proliferation).
Studies have shown that thanks to the use of pomalidomide, the level of progression is reduced by 52%, and life expectancy is significantly increased.
The described substance has been approved in the United States for the treatment of refractory multiple and recurrent myeloma. There it is produced under the trade name "Pomalist", and in the EU it is known as "Imid".
Where can I buy cheaper drugs containing pomalidomide
Before we continue the description of the action of pomalidomide, it should be said that the drugs needed in the treatment of cancer are expensive. And the problem for patients is that there is no way to interrupt treatment, and paying for the entire course is very problematic. So, in Moscow, for a branded drug containing pomalidomide, the price is around 819,000 rubles.
In such a situation, a well-known site will come to the rescue. . Here you can buy generics containing the same active substance - pomalidomide, but the price for them will be noticeably more affordable. And this is due not to the poor quality of the drug, but to the fact that the well-known Indian company that produces it did not have to invest in research, development and advertising. She only bought the right to manufacture the drug, which explains its relatively low cost, with the same effectiveness.
Method of use of the drug and its dosage
Pomalidomide is indicated in the treatment of patients over 18 years of age in whom the progression of refractory multiple myeloma is noticeable after at least 2 courses of treatment with lenalidomide and bortezomib.
Apply the drug inside, together with dexamethasone, 4 mg once a day, for 21 days, after which a break for a week is needed.
The drug should be taken at the same hours, every day, regardless of the meal time. Capsules cannot be chewed or broken. If one dose was missed, then the next day you do not need to drink a double dose of the drug.
With the progression of the disease, treatment is suspended.
Contraindications
Do not prescribe drugs containing pomalidomide to children under 18 years of age and pregnant women. Breastfeeding for the period of treatment with the named agent should be discontinued.
The condition of patients with renal and hepatic insufficiency should be monitored by the attending physician in order to timely detect an undesirable reaction.
Side effect
When treating with drugs containing pomalidomide (Imdovid, Pomalist, etc.), the following negative effects may occur in patients:
- fatigue;
- the occurrence of headaches, dizziness and confusion;
- nausea, vomiting;
- decreased appetite;
- digestive tract disorders;
- anemia, thrombocytopenia;
- the occurrence of muscle cramps and bone pain;
- the development of infectious diseases of the upper respiratory tract;
- the appearance of a rash.