Modern living conditions make most of us remain in a state of constant stress, which cannot but have a negative impact on our health, both physical and psychological. Increasingly, the tension becomes so strong, and the condition is so severe that the situation forces a person to seek professional help, since he is already unable to cope with stress on his own.
Alarming symptoms, which, as a rule, do not go unnoticed, are sleep and wakefulness disorders, extreme manifestations of emotions, inability to lead a previous lifestyle. It is important to consult a doctor in time, who will be able to provide the necessary assistance, drawing up a competent treatment regimen and prescribing the necessary medication. Many consider the drug "Valdoxan" to be effective. Reviews of people about well-being after using this drug will be described in detail in this article. Among other things, it will give answers to the following questions: what is the principle of action of the drug in question? In what cases would it be rational to use it? What are the potential side effects? Be careful and do not miss a single detail.
Structure
The main active ingredient of the drug "Valdoxan" reviews and instructions for use are called agomelatine. In one tablet, the content of this substance reaches 25 mg. This is enough to ensure that the drug in question is sufficiently effective and does not interfere with the normal course of the patient's life.
Indications
Instructions for use and reviews of people "Valdoxan" is described as an antidepressant. Its action is aimed at stimulating the release of dopamine and norepinephrine, in particular in a certain area of the cerebral cortex - the prefrontal zone. Despite this, it does not affect the level of extracellular serotonin. The active substance of the drug in question stimulates melatonin receptors. This helps to restore circadian rhythms and the structure of sleep itself.
As a rule, specialists include this medication in the course of correction of major depressive disorder in adult patients.
Contraindications
Instructions, reviews about "Valdoxan" recommend paying special attention to what contraindications the medication in question has. In some cases, the use of this drug is undesirable or even completely prohibited. It is important to know for sure whether you are also at risk, so that treatment with the drug in question does not harm you. So, in what cases is it forbidden to use "Valdoxan" reviews of doctors and instructions? The following are distinguished:
- personal intolerance or allergy to the main active ingredient of the drug agomelatine;
- childhood;
- lactose intolerance by the patient;
- if at the same time some powerful CYP1A2 inhibitors are used, such as ciprofloxacin or fluvoxamine;
- in the presence of liver failure (including with liver diseases in the active phase, or with cirrhosis);
- the period of breastfeeding (if the treatment with the drug in question can still not be dispensed with, then breast-feeding should be stopped).
In some cases, the use of this medication, although possible, should be carried out with caution under the supervision of an experienced doctor. These are the following options:
- the patient is in advanced age (people over 65 years old are meant);
- suicide attempts have already taken place;
- the patient abuses alcohol or is prone to such excesses (as noted by reviews, Valdoxan and alcohol are incompatible);
- moderate CYP1A2 inhibitors are also included in the course of treatment (we are talking about substances such as grefafloxacin, propranolol or enoxacin);
- the presence of dementia in an elderly patient;
- previously had manic or hypomanic episodes;
- developing pregnancy;
- the use of any hepatotoxic drugs;
- in case of large depressive episodes in patients who have moderate or pronounced renal failure.
If you know that you have one or more of the above conditions, tell your doctor. This will help him to correctly draw up a treatment regimen that takes into account all your individual characteristics. Such an appointment will be truly effective.
Mode of application
How do experts recommend taking the drug "Valdoxan"? The reception scheme is quite simple. Tablets should be taken orally, swallowing whole and in no case chewing. At the time of eating, there is no need to navigate.
Doctors recommend taking only one tablet per day containing 25 mg of the active substance. It’s better to do it in the evening. If, within two weeks, the specialist did not notice positive dynamics, then perhaps he will decide to increase the therapeutic dosage to 50 mg (you will have to drink 2 tablets once a day in the evening).
Overdose
Unfortunately, at the moment there is no exact data on the dangers that an overdose of the drug in question entails. Nevertheless, it is possible to describe the alleged symptoms, which, most likely, can be characterized by an overdose of this medication. Among them are the following:
- malaise;
- drowsiness;
- anxiety;
- cyanosis of the skin (or cyanosis);
- dizziness;
- pain in the pancreas;
- weakness;
- general stress;
- anxiety;
- strong emotional arousal (or agitation).
One universal antidote for an overdose of Valdoxan does not exist. If the patient notices the development of one or more of the symptoms described above, he should immediately contact his doctor. Only a specialist can properly remove the patient from this condition. As a rule, symptomatic treatment is prescribed. And the patient is under the supervision of doctors in highly specialized departments for some time.
Side effects
The use of the drug "Valdoxan" can lead to the development of certain side effects. Some of them can be extremely unpleasant, while others can even be dangerous. It is important not to neglect the fact of their appearance and in time to seek help. To do this, you need to know exactly what to pay attention to. Among the most common side effects are the following:
- blurred vision;
- the development of excessive drowsiness or, conversely, insomnia;
- the appearance of obsessive nausea;
- noticeable abdominal pain;
- severe back pain;
- migraine;
- heavy sweating;
- impaired liver function (e.g., hepatitis, jaundice, or liver failure);
- feeling of anxiety;
- feeling of anxiety;
- the emergence of suicidal thoughts;
- attempted suicide;
- the development of constipation or diarrhea;
- recurring nightmares;
- dizziness;
- itching of the skin;
- irritability;
- the occurrence of unusual dreams;
- headaches;
- constant fatigue;
- noticeable aggressiveness;
- paresthesia;
- the occurrence of hallucinations;
- a sharp decrease or increase in patient weight;
- a state of intense emotional arousal (or agitation);
- eczema;
- development of mania or hypomania;
- the occurrence of an erythematous rash.
Do not ignore the onset of these symptoms. Timely assistance of a specialist will help to significantly reduce their manifestation and avoid negative consequences for the patient’s health. Be especially attentive to your health when using the drug in question.
Positive customer reviews
Reviews "Valdoxan" receives the most diverse. This is due both to the correction of which particular disorder he is prescribed by a specialist, and to how sensitive the body of a particular person to the action of the main active component of this medication. Patient reviews of Valdoxan are traditionally divided into two camps: those who are completely satisfied with the effectiveness of the drug in question, and those who consider it absolutely useless or even harmful. Next, we discuss what are the main advantages of this drug.
Positive reviews of "Valdoxan" describe the following positive features of the drug:
- A rare manifestation of side effects.
- Patients talk about the disappearance of tearfulness and excessive emotionality due to the use of Valdoxan tablets. Reviews also note a significant improvement in the quality of sleep in those who take the medication in question.
- Lack of addiction and withdrawal.
- Obvious positive result from the use of the drug.
- Proper packaging design (provides for the separation of individual days of the week for ease of use).
- Performance Improvement.
- Positive effect on mood.
For many, the use of the drug in question was a real salvation in the fight against their ailments. The advantages described above for these patients were enough to start treatment with the drug "Valdoxan". Reviews of people, however, show that the drug in question also has a number of significant drawbacks. What exactly is it about? We consider in more detail below.
Negative customer reviews
As reviews of Valdoxan show, the well-being of people after its use does not always improve significantly. Some do not notice any positive changes, while others suffer from the manifestations of numerous side effects. Feedback on the use of "Valdoxan" allows us to highlight the following negative aspects of its use:
- According to reviews, the drug "is not suitable for some patients. Such people do not notice any positive effect from the use of the drug.
- It can affect the feeling of fullness and, as a result, affect weight.
- It is often ineffective in combating irritable bowel syndrome.
- It does not always help to eliminate a sense of anxiety.
- The drug is relatively expensive.
- Judging by the reviews, Valdoxan can change the perception of reality.
- A large number of possible side effects.
- Increased anxiety, developing at the beginning of the drug.
- Sometimes causes insomnia.
Since one of the significant drawbacks of the drug in question is its high cost, many ask their doctors to prescribe them cheaper medicines - analogues of Valdoxan. Reviews highlight the following drugs in this group: Neuroplant, Azafen, Venlafaxine. Their cost is much more attractive to patients. The effectiveness of such analogues is evaluated individually. Remember that changing your appointment yourself is not recommended. Such adjustments can be made only by the attending physician, who is well acquainted with the history of your disease and the features of the development of your disorder.
The presence of such a number of negative aspects makes many seriously think about whether to start treatment with its use. If you have such doubts, hurry to get a specialist consultation. A competent attending physician will be able to check the rationality of the appointment and, if necessary, prescribe a more suitable medication.
Storage conditions
Reviews, instructions for use of "Valdoxan" notice that there is no need to create special conditions for the storage of the drug or its transportation. However, it is important not to remove the tablets from their original packaging until immediately before use. The shelf life of the medication in question is three years from the moment it was manufactured.
Parents should worry in advance about the safety of their children and limit their access to the drug in question. Uncontrolled intake of the medication in question can lead to detrimental health effects.
Finally
The features of using the drug "Valdoxan", reviews of people about their well-being after it were discussed in detail above. Many find the drug in question extremely effective. So, some patients call it a real salvation, because only this drug helped them get rid of the mental disorders that tormented them so. Others, on the contrary, find it overrated, ineffective, or even harmful (since their condition not only did not improve, but, on the contrary, worsened). In order for the drug to have the desired effect, it must be prescribed in accordance with all the prescribed rules. Such an appointment cannot be made independently, as the patient is not able to give an objective assessment of his condition and does not have enough knowledge to make a diagnosis and select a treatment regimen. Having entrusted your health to a specialist, you will be able to receive qualified help and, with a greater probability, fully restore your mental and emotional balance.
It is important to carefully monitor your well-being during the treatment process. Do not forget that side effects from taking the drug can cause no less inconvenience than an ailment in itself. Therefore, it is extremely important to immediately respond to any unpleasant symptoms. Not only his current state of health, but also the effectiveness of the entire course of treatment as a whole depends on how quickly the patient receives the necessary help. Do not try to neutralize the manifestations of side effects yourself. Similarly, you cannot arbitrarily replace one antidepressant with another, even if it seems to you that it is great for correcting your condition and has few side effects. Illiterate treatment can soon worsen the symptoms, which will require the use of more powerful drugs that have a much stronger effect on the patient's body, which, of course, is undesirable.
Be mindful of your health. Many problems can be avoided without neglecting the necessary rest and having a healthy regime of the day. If difficulties nevertheless arose, take the treatment prescribed by your doctor seriously. Learn as much as possible about the drug, its effectiveness and strictly follow the recommendations of a specialist.