The medicine "Omeprazole" is included in the category of antiulcer drugs. The drug is able to inhibit the "proton pump" (a special enzyme) in the gastric parietal cells, thus blocking the synthesis of hydrochloric acid at the final stage. As a result, regardless of the type of stimulus, the level of stimulated and basal secretion decreases. With a single oral administration, the effect is noted during the first 60 minutes, the maximum effect reaches after 2 hours and lasts throughout the day. With peptic ulcer, 20 mg of the drug contribute to maintaining intragastric pH = 317 hours. After the end of therapy, the restoration of secretory activity occurs after 3-5 days. The drug is absorbed quickly enough. The bioavailability of the drug is 30-40%. Metabolism occurs in the liver. The drug is excreted by the kidneys mainly.
Medication "Omeprazole". Instruction Indications
The drug is recommended for peptic ulcer, erosive peptic ulcer lesions in the digestive tract, with Helicobacter pylori eradication.
Contraindications
Do not prescribe medication during pregnancy, breastfeeding, in childhood. The drug "Omeprazole" instruction does not allow for use in case of hypersensitivity.
Adverse reactions
As a rule, negative consequences during treatment are rare and reversible. The drug can cause constipation or diarrhea, an upset liver function, depression, pancytopenia, dizziness. Due to the administration of the drug, taste disturbance, the occurrence of muscle weakness, agranulocytosis, photosensitivity are likely. Against the background of treatment, dry mouth, soreness in the abdomen, hepatitis, stomatitis, flatulence, arthralgia, erythema multiforme, angioedema may occur . The instructions include gynecomastia, the formation of gastric cysts (during long-term therapy), fever, visual impairment, increased sweating, and peripheral swelling as negative manifestations during treatment with Omeprazole. The drug can cause anaphylactic shock, alopecia, myalgia, interstitial nephritis, bronchospasm.
How to take Omeprazole
The medicine is intended for oral administration. Capsules do not chew. With exacerbation of peptic ulcer in the duodenum, 1 capsule is prescribed once a day. The duration of treatment is 2-4 weeks. In some cases, the dosage is increased to two capsules per day. Because of stomach ulcers and erosive-ulcerative esophagitis , 1-2 capsules are recommended for 4-8 weeks. With eradication, Helicobacter pylori is prescribed on a capsule twice a day. The duration of treatment is a week in combination with antibacterial drugs. In case of erosive and ulcerative lesions in the gastrointestinal tract, the omeprazole agent recommends a capsule per day. Duration of admission is a month or two. With anti-relapse therapy, the dosage of the drug is a capsule per day. The duration of admission is set by the doctor individually.
Medication "Omeprazole". Instructions for use. Price
The cost of the medicine is up to one hundred rubles.