The drug "Ceftriaxone" refers to the pharmacological group of cephalosporin antibiotics, has bactericidal and antibacterial properties. The medicine has a wide range of effects, destroys the biosynthesis of mucopeptide of the bacterial cell walls , inhibits the transpeptidase.
The drug is made in the form of a white or yellowish-orange powder for the preparation of injections in bottles of 0.5, 1 and 2 grams. The substance is easily soluble in water, the color of the injection, depending on the shelf life, varies from yellow to amber.
The drug "Ceftriaxone": indications for use
The medication is prescribed for the treatment of infectious manifestations that are caused by microorganisms sensitive to the antibiotic. The list of indications includes infections of the ENT organs, lower and upper respiratory tract, any form of bronchitis, pleural empyema, lung abscess.
The Ceftriaxone drug is effective for pneumonia, infectious pathologies of soft tissues and skin infections, streptoderma. The antibiotic is used to treat the genitourinary system, pyelonephritis, pyelitis, prostatitis, cystitis, epididymitis, gynecological infections, and simple forms of gonorrhea.
The medicine is used to destroy microorganisms that affect the organs of the abdominal cavity, gastrointestinal system, and bile ducts.
It is worth using the drug “Ceftriaxone” for sinusitis, for the treatment of peritonitis, sepsis and bacterial septicemia, endocarditis and meningitis, osteomyelitis, syphilis, soft chancre and spirochetosis.
In some cases, an injection is prescribed for the treatment of salmonellosis, typhoid fever, as well as for the prevention of purulent, septic complications after operations.
The drug "Ceftriaxone": indications for use and method of application
The antibiotic is administered intravenously and intramuscularly. Only fresh solutions can be used for treatment.
When administered intramuscularly, the powder is dissolved in sterile water intended for injection. To use half and 1 gram of the drug, take 2 and 3.5 ml of water, respectively. Injections are injected deep enough into the outer upper part of the gluteal muscle (not more than 1 g in one place). To eliminate pain, it is possible to use a one percent solution of the drug "Lidocaine".
With intravenous treatment, the antibiotic is dissolved in sterile water for injection in the ratio of 0.5 g to 5 ml. The solution is injected into the vein slowly for three to four minutes.
The drug "Ceftriaxone": indications for use and side effects
In general, the antibiotic is well tolerated by patients. However, in some cases, vomiting, nausea, diarrhea, cholestatic jaundice, hepatitis, pseudomembranous colitis can occur . When using the medicine, allergies are possible, manifested in the form of skin itching and rash, eosinophilia. From the urinary system, a reaction in the form of interstitial nephritis is possible , and from the circulatory side, hypoprothrombinemia can be observed.
The drug "Ceftriaxone": indications for use, contraindications and overdose
The drug is not prescribed for hypersensitivity to the drug, penicillin and other cephalosporins. The use of the drug in the first trimester of pregnancy, with breastfeeding, with renal or liver failure is unacceptable.
With long-term treatment with Ceftriaxone using high doses, the blood picture (thrombocytopenia, hemolytic anemia, neutropenia, leukopenia) can change. High excess plasma concentrations of the substance cannot be reduced by peritoneal or hemodialysis, therefore symptomatic treatment is prescribed in such cases.