A person can feel great, go to work, do everyday chores, and only after blood donation he learns about the diagnosis of “hyperlipidemia”. This is a pathology in which the level of triglycerides and cholesterol in the body rises. The insidiousness of the disease lies in its asymptomatic course. But it is he who increases the risk of atherosclerotic plaques. And those, in turn, can lead to a heart attack, stroke. The Krestor preparation allows to prevent such serious consequences in a timely manner. This is an effective medicine of the last generation. Let us consider in more detail the instructions for use and the main analogues of Krestor.
Release form, composition
The medicine "Crestor" is available in the form of tablets.
However, depending on the amount of active ingredient - rosuvastatin - several types of pills are made:
- Some of them are yellow. Pills are biconvex, round. Engraved on their surface is ZD4522 5. Each tablet contains 5 mg of the basic substance.
- Other pills are pink. They are also biconvex, round. But they already contain 10 mg of the active substance. The engraving on such tablets is as follows: ZD4522 10.
- Pills containing 20 mg of rosuvastatin are available. They are also pink in color. They are distinguished by the engraving ZD4522 20.
- There are tablets in which the main substance contains 40 mg. These pills are pink, but oval. ZD4522 is engraved on one surface of the tablet, and 40 on the other.
All medicines - both the original drug and any analogue of "Crestor" - are sold only by prescription.
Drug action
The drug "Crestor" is a modern lipid-lowering agent. It is often used for the prevention and treatment of atherosclerosis.
The active components that make up the medication provide the following effects on the body:
- hypocholesterolemic;
- lipid-lowering.
Its effectiveness is confirmed by patient reviews. They testify that the Krestor drug is one of the best remedies for cholesterol. In this case, the medication is practically well tolerated by almost all patients.
The beneficial effect of the drug is noticeable after a week. However, the maximum effect occurs only after 14-30 days of taking the drug "Crestor". Instructions for use (analogues also do not work immediately) warns about this.
Analogues of the drug can have a toxic effect on the liver. The drug "Crestor" compares favorably with them. Since it does not adversely affect an important organ.
The medicine may be the only drug in the treatment of hypercholesterolemia, hyperlipidemia. Sometimes it is recommended to use it as a dietary supplement. And in some cases, it, in combination with other medicines, constitutes a cholesterol lowering treatment.
In pharmacies you can find a great analogue of "Crestor". But this issue should initially be resolved with the doctor.
Indications for use
When choosing an analogue of "Crestor", be sure to consider under what conditions the product is recommended for use.
The original medication has the following indications:
- primary hypercholesterolemia;
- stroke prevention;
- mixed hypercholesterolemia;
- heart attack prevention;
- familial homozygous hypercholesterolemia;
- atherosclerosis;
- hypertriglyceridemia.
Dosage of medication
Only the doctor prescribes Krestor tablets. Dosages depend on the stage of pathology and the risk of developing heart ailments.
Doctors recommend that the following rules be followed during treatment with this medication:
- The pill should not be crushed. It is swallowed whole.
- Take the drug at any time. Its use is not dependent on food intake.
- Before therapy with the drug "Crestor", the patient must be transferred to a lipid-lowering diet. It continues while taking pills.
- The dose of medicine is selected individually. As a rule, at the beginning of therapy, it is 5 or 10 mg. The tablet is used 1 time per day.
- In case of poor treatment effectiveness, an increase in dose is possible only after 4 weeks of therapy. In this case, the patient is recommended to take a pill containing 20 mg of the main substance once a day.
- It is extremely rare that the maximum dosage of the drug is prescribed. It is indicated only for those patients who are diagnosed with a severe stage of hypercholesterolemia and there is a high risk of developing cardiac and vascular pathologies. In this case, a dosage of 40 mg is indicated if the undertaken treatment with 20 mg tablets did not bring the desired effect.
- Patients who are recommended to take the maximum dose of the drug are under the constant supervision of doctors, since there is a high risk of developing adverse side effects.
- After 2-4 weeks, people who use high doses of the drug must monitor lipid metabolism. Depending on the test results, the settings are adjusted.
Side effects
Patients, subject to the dosage prescribed by the doctor, rarely encounter negative consequences from taking the “Crestor” drug. Reviews of people confirm this.
According to the instructions, such reactions may occur:
- Gastrointestinal tract: nausea, pain in the abdomen, constipation.
- Nervous system: dizziness, headache often occurs.
- Skin: itching, hives, sometimes a rash.
- Immune system: angioedema is rarely manifested.
- Musculoskeletal system: myalgia, rhabdomyolysis, myopathy.
- Urinary system: proteinuria.
Contraindications
The drug "Crestor" has a number of limitations. Be sure to read them before using the drug.
Tablets (10 mg, 20 mg) are contraindicated:
- with increased sensitivity;
- liver diseases that occur in the active stage, including with a persistent increase in serum transaminase activity;
- severe violations in the work of the kidneys;
- myopathy
- the simultaneous use of Cyclosporin;
- pregnancy
- lactation period;
- lack of adequate contraception;
- predispositions to the occurrence of myotoxic complications.
40 mg pills have the following intake restrictions:
- hypersensitivity;
- simultaneous therapy with the Cyclosporin medication;
- pregnancy, lactation;
- ineffective methods of contraception;
- liver pathology, which are diagnosed in an active form;
- hypothyroidism;
- renal failure;
- a history of muscle disease (either personal or family);
- alcohol abuse
- myotoxicity as a result of taking other drugs;
- conditions that provoke an increase in the concentration of rosuvastatin;
- simultaneous therapy with fibrates;
- Asian race.
Analogues of the drug
Today you can pick up quite effective substitutes for Krestor. However, do not rush to do it yourself. Do not forget, if you were prescribed the original medicine, then the Krestor drug is perfect for your body and the ailment that you have to fight. Therefore, to independently select other medicines is not only undesirable, but it can also be dangerous.
The most basic analogue of “Crestor” is the medication “Rosuvastatin”. However, the pharmaceutical market is able to offer other means, no less effective.
Excellent analogues of the original drug are medicines:
- "Rosistark".
- Rosart.
- "Akorta."
- Mertenil.
- Tevastor.
- "Rosucard."
- "Roxer."
- "Rosuvastatin Calcium."
- Rosicore.
- "Rustor."
- "Rosuvastatin-SZ".
- "Rosulip."
Cost of medicines
Very often, the need to replace the original product arises as a result of its high price. Unfortunately, many cannot afford the purchase of the Krestor medicine. Analogs, the price of which is much lower, are an excellent alternative in this case. Just do not forget to consult with your doctor initially.
So, we will get acquainted with the prices of the original medicine and the main analogues:
- the drug "Crestor" No. 28 (10 mg) - 1676 rubles .;
- Krestor medicine No. 28 (20 mg) - 2825 rubles;
- tablets "Akorta" No. 30 (10 mg) - 511.40 rubles .;
- Medication "Akorta" No. 30 (20 mg) - 1049.50 rubles .;
- Mertenil agent No. 30 (10 mg) - 663 rubles;
- Mertenil drug No. 30 (20 mg) - 1045 rubles;
- Rosuvastatin medicine No. 30 (10 mg) - 478.70 rubles;
- Rosuvastatin tablets No. 30 (20 mg) - 622.30 rubles.
What do doctors and patients think about the drug?
Of course, in the first place, the opinion of people who are faced with this drug is important. What do doctors say about the Krestor medication? Doctors' reviews indicate that in patients who were prescribed this drug, cholesterol levels were perfectly reduced. At the same time, in most of them, the indicator reached a normal mark just a week after the start of taking the drug.
Doctors note that this medication is well studied, has a large evidence base. The tablets are of high quality. Therefore, this medicine in comparison with other medicines of this group works more efficiently. Often it is well tolerated by the body.
It is simply amazing, but the Krestor medicine belongs to the category of drugs about which the opinions of doctors and patients completely coincide. People who have been prescribed the drug note that the pills help to lower cholesterol. This is evidenced by all patients who use the medicine.
Most often, reviews are left by patients who have had a heart attack or stroke. They indicate that the medication is very effective. However, some of them had to drink pills for about a month, so that a high rate dropped to normal.