Many people suffer from symptoms of allergic rhinitis. This problem is especially typical for residents of megacities. This article will focus on the principles of the drug and its proper use.
Pharmacological properties and composition
Avamis is an effective nasal preparation that comes in the form of a spray. The product contains a fluorinated corticosteroid, which is an active inhibitor of cell activation. The active substance of this drug is fluticasone furoate, which has a pronounced anti-inflammatory effect on the body. The active substances of this drug are metabolized in the liver with the active participation of the cytochrome P450 enzyme CYP3A4. Avamis is an effective hormonal drug for topical use in diseases of the nasal cavity. The active substance of this drug is rapidly introduced into the body and begins to participate in the processes of primary metabolism in the liver. Reviews about Avamis from allergies are mostly positive. Patients note its affordable price at the pharmacy.
The active substance of fluticasone furoate binds to plasma proteins by more than 99%. The substance is rapidly excreted from the bloodstream through the metabolic process in the liver. Oral administration involves the removal of this substance in a natural way. About 2% of the metabolites are excreted by the kidneys.
Indications for use
Allergic rhinitis is a fairly common disease. Statistics show that about 20% of people suffer from it. This type of rhinitis occurs as a result of inflammation of the mucous membrane in the nasal passages due to the ingestion of certain substances. The first signs of the disease may appear in the first few seconds of interaction with the allergen. the drug is applied topically, therefore, quickly and effectively eliminates the first symptoms of the disease. Testimonials about Avamis at rhinitis show that recovery comes rather quickly.
The tool eliminates allergic rhinitis and restores the human immune system. Reviews about Avamis from allergies are mostly positive. Patients believe that the drug has no analogues and is very effective. This tool is indicated for use by people who suffer from allergic rhinitis. The drug is prescribed as symptomatic therapy and is one of the most effective.
The scope of this drug is limited only to the removal of the symptoms of allergic rhinitis. In other words, the use of this tool eliminates nasal congestion. There are various reviews about Avamis, among which you can find negative ones. Experts do not recommend the use of this tool without a doctor’s prescription when a common cold occurs that has arisen against a background of a bacterial infection. The doctors' comments about Avamis for sinusitis show that the drug is not capable of exerting the necessary effect on this ailment. This situation is due to the narrow specialization of this drug. You can give Avamis to children. Reviews of doctors about this drug have a positive orientation, since the tool has proven effective in treating allergic rhinitis in small patients. However, the drug is highly specialized, therefore, does not help with other diseases due to the specificity of the action. That is why the reviews of doctors about Avamis for sinusitis and some other diseases have a negative focus. Treatment with this drug is prescribed only by a specialist.
The drug is not addictive, and can also be used by children with adenoids. This unpleasant disease is characterized by enlargement of the tonsils covering the nasopharynx. Reviews about the Avamis spray for children with adenoids are positive, because the drug actively affects the cause. This tool allows you to facilitate breathing, swallowing and chewing food. You can find many positive reviews of doctors about Avamis for adenoids in children. It should be borne in mind that children over 2 years old can use the drug. Spray perfectly relieves swelling in the nasal passages and has an anti-inflammatory effect.
Most reviews of the Avamis spray for adenoids boil down to the fact that the drug does not cause side effects. Many note a significant improvement in breathing while taking the medication. Patients leave numerous positive reviews about Avamis: polyps quickly pass, health improves. This allows you to lead a normal lifestyle without difficulty breathing. In addition to the listed advantages, the drug has a very affordable price.
Mode of application
The drug is administered intranasally through the nasal cavity. The product is valid for 8 hours after use. The effect is achieved a couple of days after the start of the use of the product. The drug is injected into each nostril twice a day. Children are recommended to make one injection once a day. To achieve maximum effect, you must regularly use the drug. Before new use, shake the bottle well. Reviews about Avamis for children with allergic rhinitis can only be heard positive, since the drug quickly removes the symptoms of the disease.
The bottle has a special protective cap on the sprayer and a special window in which you can see the level of the drug. Before using the medicine, it is recommended to shake the bottle well. You can make several injections into the air and only then, when inhaling, direct the nebulizer into the nasal passage. In this case, the bottle must be kept upright. You can press the spray gun with two fingers. After using the drug, it is recommended to exhale through the mouth. Then wipe the spray gun with a tissue and close the lid tightly. Experts do not recommend:
- Do self-cleaning spray.
- Prevent moisture from entering it.
- Leave the product open.
- Spray into eyes.
If the nebulizer does not work, check the level of the medicine in the vial. Also check the tip for contamination. The drug shows high efficiency in specialized applications. The drug is available in bottles of various capacities of 30, 60 and 120 doses. After each use of the drug, it is necessary to care for the nebulizer. To do this, just wipe its surface with a napkin or dry cloth. In the event that liquid has entered the sprayer, wipe it and leave it in the open air without a protective cap. After a few minutes, you can press the spray gun and activate it. It is not recommended to clean the spray gun with pins or other sharp objects. This will prevent the clogging of the sprayer and ensure its maximum tightness. As a result, the composition of the drug will retain its unique properties for a long time.
Mechanism of action
The effect of the drug is based on the anti-inflammatory effect of glucocorticosteroids. The drug is sprayed into the nasal region, which leads to the rapid interaction of active substances with inflammatory factors. The substance allows you to suspend the production of these factors and quickly eliminate edema. This tool is used to relieve symptoms of allergic rhinitis, such as nasal congestion, burning of the mucous membrane, redness, lacrimation.
The active substance is associated with receptors in the nasal cavity for 24 hours. Therefore, to achieve maximum effect, a single use of the drug is enough. The tool has a high bioavailability, therefore, it is rapidly and completely metabolized in the liver. Due to this, the concentration of the active substance in the plasma is predictable and controlled. Since the drug is applied topically, it is practically devoid of the disadvantages that are characteristic of conventional hormonal drugs. Thus, Avamis is considered one of the most effective and safe drugs.
The medication is a unique drug that contains the active component of fluticasone furoate. Other analogues fight disease based on the vasoconstrictor principle of action. They only complicate the treatment process, since such drugs have a large number of side effects. For example, with an overdose, sleep disturbance, increased heartbeat, the appearance of pallor, stomach pain, etc. are possible. Similar drugs are also contraindicated for children under 6 years of age. At the same time, according to reviews, there are practically no side effects from Avamis in children. The drug has a powerful anti-inflammatory effect and quickly eliminates allergic reactions. Since the solution is sprayed through the nasopharynx and sinuses, a large number of receptors on the mucous membrane are activated and their activity decreases. The tool helps to eliminate puffiness and narrowing of blood vessels. The spray is ideal not only for treating allergies during the flowering period of plants, but also for combating allergies to wool, dust and other provocateurs. Interacting with nasopharyngeal receptors, the drug prevents a reaction to external stimuli. Therefore, a person does not manifest sneezing, itching and a runny nose.
Contraindications
The drug is actively prescribed for children. The doctors' comments about Avamis prove that the remedy is absolutely safe. However, the drug is not prescribed to persons under the age of six. Also, it is not recommended to use the drug for patients who have severe liver disorders. In this case, it is necessary to consult with your doctor and use the drug in small doses with extreme caution. According to reviews, the drug "Avamis" is prescribed even for pregnant women. During the period of gestation, the spray is used in minimal doses.
Experts do not recommend the use of the drug for people under the age of two years, as well as for people who have severe liver and kidney pathologies. During pregnancy, this drug can be used only if the expected harm from allergies is much higher than the alleged harm that can be caused to the fetus. The exact effect of the drug on the embryo is not well understood. There is also no reliable data on the transfer of substances during breastfeeding. While taking this drug, mothers are advised to refuse breastfeeding.
Side effects
When taking the drug, some side effects may occur, as evidenced by reviews about Avamis. Many have noticed various disorders that relate to ulcerative lesions of the nasal mucosa or the appearance of nosebleeds. Some people have allergic reactions, which are expressed in swelling, itching of the skin and a rash on the epidermis.
Therefore, reviews of the side effects of Avamis are rather contradictory, since the manifestation of certain reactions depends on the characteristics of the patient’s body. In some cases, a manifestation of growth retardation is possible, especially with prolonged use of the drug. Still, the reviews about the Avamis spray for children with adenoids are almost positive, since the drug helps to quickly get rid of the symptoms of allergic rhinitis.
The listed phenomena are manifested depending on the individual characteristics of the human body. It is not recommended to use the drug for more than six weeks. The risk of various side effects increases significantly with the joint use of this drug with other drugs that belong to the category of glucocorticosteroids.
Drug overdose
To date, there is no reliable data on drug overdose. This drug does not have systemic side effects and strict limitations. Strict adherence to instructions and short-term use reduces the risk of any side effects. To achieve the maximum effect of taking the drug, it will take about eight hours. In order to obtain a stable positive effect, it will take two days. The doctor will clarify this information during the consultation. From the age of twelve, you can start taking the drug in an increased dose, which is two injections into each nostril. When the desired effect is achieved, it is recommended to reduce the dose to one spray. In some cases, bleeding from the nasal openings may be observed. Some patients notice ulceration of the mucous membrane. The listed symptoms can occur only with prolonged treatment with large doses. Clinical trials have shown that in adult patients, side effects are much more common than in children. Most often, patients using this medicine have nosebleeds. Typically, these unwanted effects accompany long-term treatment with large doses. So, in adult patients receiving large doses, bleeding is more common than in children.
Medical supervision
Experts recommend using Avamis in case of adenoids in children. This drug can improve the health status of young patients. However, there have been cases of small sores on the mucous membrane and the appearance of nosebleeds. The drug is dispensed, as a rule, only by prescription. Certain categories of patients need to take the drug with great care. In this case, maximum attention to internal health during the period of taking the drug will be required. This category of patients includes people with moderate and severe hepatic impairment, allergic to the components of the drug, pregnant women. For these patients, this hormonal drug is rarely prescribed in the presence of circumstances in favor of the fact that the benefits of drinking will be much higher than the possible harm. The drug does not affect the concentration of attention, so it can be used even if you need to drive a vehicle. This tool does not cause drowsiness, so people often use it for their treatment. The drug has helped many patients restore normal nasal breathing. The healing process is significantly accelerated as a result of the use of complex therapy using antihistamines.
Patient Reviews
Many people note the high effectiveness of this drug and ease of use. Therefore, reviews about Avamis are mostly positive. The tool perfectly eliminates the feeling of discomfort and minimizes swelling of the nasal mucosa. However, some users are embarrassed that this product belongs to the category of hormonal drugs. The spray allows you to quickly get rid of nasal congestion and swelling and significantly improves the transportation of active substances to the site of inflammation.
There is a belief that many hormones cause harmful effects on the human body. However, this is a mistake, since this drug belongs to the category of modern hormonal drugs. Proper use and following the instructions can reduce the risks of side effects. The drug has an effect only in the area of application, therefore, minimizes the likelihood of a toxic effect. Clinical studies have revealed that the drug is metabolized by the liver and does not affect the kidneys. Also, the connection of this drug with blood proteins prevents the finding of its free form in blood plasma. Conventional medicines have a positive effect only after a series of chemical transformations in the human body. Such reactions, in certain cases, can have a toxic effect. The formula of the active substance of the drug "Avamis" reacts immediately with the inflammation factor in its original form. Subject to the indicated dosage of the drug, it has a beneficial therapeutic effect. You can give Avamis nasal spray to children. Reviews about this drug are only positive, despite the fact that it belongs to the category of hormonal drugs.
Some patients complained of nosebleeds and the appearance of urticaria. However, proper diagnosis and proper administration of this drug reduces the risk of any side effects to a minimum. Ineffective treatment with a remedy is direct evidence of misuse and prescription. «» , . .
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Many patients note that the drug has high efficiency and ease of use. This spray perfectly eliminates swelling of the nasal mucosa and eliminates the discomfort during seasonal allergies. Nasal treatment helps to eliminate nasal sinus congestion and swelling of the nose. Also, the drug significantly improves the transportation of active substances to the site of inflammation. Experts recommend using this tool with the appearance of adenoids in children. The spray can be used without fear, since it has passed many clinical trials. Nevertheless, the attending physician must make decisions.