The drug "Lopirel" belongs to the category of medicines that have anti-aggregation effect. The active ingredient is clopidogler hydrosulfate.
Indications
Means "Lopirel" (instructions for use indicates this) is prescribed for the prevention of atherothrombosis. The medication is recommended for patients after ischemic stroke, myocardial infarction or people with a diagnosed peripheral artery disease. The medicine is prescribed for patients with acute coronary syndrome without an increase in the ST segment (with unstable angina or heart attack without a Q wave on the ECG). In this case, the medication is taken in combination with acetylsalicylic acid.
The medicine "Lopirel." Instructions for use. Contraindications
It is not allowed to take medication for hemorrhagic syndrome, intracranial hemorrhage, and conditions predisposing to its occurrence, with hypersensitivity. Contraindications include the stage of exacerbation of a duodenal ulcer, gastric ulcer, tuberculosis, ulcerative colitis of a non-specific nature, hyperfibrinolysis, lung tumor. Means "Lopirel" (instructions for use contains this information) is not prescribed for liver failure. For the form of a drug containing lactose, contraindications include lactase deficiency, galactose intolerance, malabsorption syndrome.
Means "Lopirel". Instructions for use. Side effects
Conjunctivitis, neuralgia, cataracts, fatigue, or dizziness are likely due to therapy. The drug can cause headaches, asthenia, paresthesia of the extremities, convulsions, arterial hypertension, peripheral edema, neutropenia, agranulocytosis. During treatment, hemorrhage in the joints, generalized edema, palpitations, hemoptysis, gastrointestinal bleeding, and purpura can be observed. Lopirel medicine (the instructions for use contain such information) can provoke hepatitis, hemorrhagic gastritis, arthrosis, back pain, arthralgia, sinusitis, pneumonia, inflammation of the upper respiratory tract, bronchitis, eczema, shortness of breath, cough, skin rash. On the basis of therapy, the development of an infection in the urinary tract, chest pain, menorrhagia, urticaria, and flu-like syndrome are sometimes noted. The occurrence of uremic (hemolytic) syndrome, anaphylactic reactions, or membranous nephropathy was rarely observed .
Dosage regimen
The drug is taken orally. The drug is prescribed for stroke, heart attack, occlusion in the peripheral arteries of 75 mg once a day. The medicine is drunk regardless of the meal. Therapy begins in the period from a few days to 35 days after a heart attack, and from a week to six months after a stroke. In acute coronary syndrome, treatment begins with a loading dose of 300 mg once. Subsequently, the amount of medication is reduced to 75 mg once a day. Combination therapy begins as soon as possible from the onset of symptoms, and lasts at least four weeks.
Means "Lopirel". Instructions for use. Price
The cost of the medication varies within five hundred rubles.