"5 nock" is an effective antimicrobial drug that has a fairly wide spectrum of action. The medicine is active against gram-positive and gram-negative bacteria, in addition, against certain subspecies of fungi, such as dermatophytes, candida and mold fungi.
The medicine is rapidly absorbed from the stomach, after an hour and a half after administration, its maximum concentration is reached. The drug is metabolized in the liver, and excreted by the kidneys and bile ducts. After taking in urine, an increased concentration is noted. Apply the drug “5 nock” for the treatment of both acute and chronic infections of the genitourinary tract caused by microorganisms sensitive to nitroxoline. It is mainly prescribed for the treatment of pyelonephritis, urethritis, epididymitis, infected adenoma, prostate carcinoma. The drug "5 nock" with cystitis also showed high efficiency. This medicine is prescribed for the prevention of infections in the period after operations on the genitourinary tract and kidneys, as well as in such diagnostic medical procedures as catheterization and cystoscopy. Sometimes the drug is taken to prevent recurrence of infections in the urinary tract.
The active substance of the drug "5 knock" - niktroksolin. It also contains various excipients. It is available in the form of 50 mg coated tablets. Tablets are usually contained in a plastic bottle, in an amount of 50 pieces. In appearance they are round, convex on both sides, shiny and covered with an orange shell.
Typically, the drug “5 knock” is recommended to take 500 milligrams per day, that is, 2 tablets 4 times a day. The dose can be increased to 800 milligrams per day. For children over five years old, it is recommended to take 300 milligrams, for children aged three to five years - 200 milligrams. Tablets should be taken before meals. The standard course of treatment can last from two to four weeks, if the need arises, therapy can be continued, but in intermittent courses. Patients who have moderate renal failure or liver failure should reduce the standard dose by half.
When using the drug, some side effects may occur. On the part of the digestive system, this is vomiting and nausea, increased activity of hepatic transaminases. From the nervous system, paresthesia, ataxia, headache, and polyneuropathy can occur. In rare cases, tachycardia may occur. An allergy in the form of a skin rash is also possible. There were also cases of thrombocytopenia and increased levels of uric acid in the blood.
The drug is categorically contraindicated in cataracts, the last degree of renal failure, high sensitivity to any of its components, and especially to nitroxoline and quinolines. You can not assign it to children under three years of age. The drug "5 nock" during pregnancy and lactation is also not prescribed, as it is contraindicated and carries a risk to the health of the child. Due to taking the medicine, urine may acquire a yellow-red tint, this is normal. You can not prescribe the drug "5 knock" at the same time as drugs that contain hydroxyquinoline or its derivatives. If the drug is used in patients with impaired renal function, constant monitoring by a qualified specialist is necessary. Without examination of the liver and kidneys, it is impossible to prescribe courses of treatment lasting more than 4 weeks. There is no data on any effect on the ability to control mechanisms and the car. Store the drug in a place not accessible to children, at room temperature. Usually, the shelf life of the medicine is five years.
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