What properties are inherent in the drug "Almiba"? Instructions for use, analogues, composition and characteristics of this medication will be presented below.
Form, composition of the medication
What is the Almiba medicine? Instructions for use states that this is an injectable solution, available in 5 ml ampoules. The active element of this tool is levocarnitine. The composition also includes the following auxiliary ingredients: water for injection, 10% hydrochloric acid.
Pharmacology
What are the properties of the drug "Almiba"? Instructions for use, reviews claim that this is a metabolic agent. Its active element is a natural substance that resembles the vitamins of group B.
This drug takes part in all metabolic processes. In this case, levocarnitine acts as a carrier of fatty acids through cell membranes from the cytoplasm to mitochondria. In them, acids undergo beta oxidation, resulting in the formation of a large amount of metabolic energy.
Features of the metabolic agent
What is remarkable drug "Almiba" (r / r int.)? Instructions for use say that this tool is able to normalize fat and protein metabolism, as well as restore alkaline blood reserves, inhibit anaerobic glycolysis and the formation of keto acids, can also reduce the degree of lactic acidosis, increase motor activity and increase exercise tolerance. It should also be noted that the mentioned drug saves the consumption of glycogen and increases its reserves in the liver.
What other properties are inherent in this medication? It exhibits an anabolic effect and, as a partial thyroxine antagonist, normalizes increased metabolism in hyperthyroidism. In addition, this tool helps to slow down the breakdown of carbohydrate and protein molecules, as well as stimulate the secretion of gastric juice.
Taking the mentioned medicine reduces the patient’s body weight (excess), reduces the amount of fat in the muscles, inhibits the development of apoptosis, has a neurotrophic effect, restores the structure of nerve tissues and limits the area of their lesions.
Kinetics of the drug
How is the absorption of the drug "Almiba"? Instructions for use informs that with parenteral administration, this drug penetrates pretty well into all body tissues. Very high concentrations of this drug are in the myocardium and skeletal muscle.
The drug is excreted by the kidneys in the form of acyl ethers. In this case, free carnitine is reabsorbed.
Indications for use of the solution
In what conditions is the patient prescribed Almiba medication? Instructions for use (the indications of this remedy will be listed right now) states that this drug is actively used for (including in pediatric practice):
- sluggish sucking reflexes and a slight increase in weight;
- nursing premature babies, as well as those who have suffered asphyxiation or birth injury;
- insufficient development of mental and motor functions, decreased muscle tone;
- hypotension, malnutrition, adynamia;
- stunted growth in adolescents under 16 years of age, mild form of thyrotoxicosis, exogenous-constitutional obesity, diabetic polyneuropathy;
- respiratory distress syndrome in newborns;
- cardiomyopathies, myocarditis, coronary heart disease, acute myocardial infarction, post-infarction conditions;
- anorexia, dementia, memory impairment, senile depression, chronic cerebral ischemia, physical exhaustion, ischemic stroke, traumatic and discirculatory encephalopathy;
- neurological manifestations in traumatic, toxic and vascular lesions of the brain;
- chronic gastritis with reduced secretion of hydrochloric acid, chronic pancreatitis, liver diseases;
- conditions accompanied by a decrease in appetite, exhaustion and weight loss;
- intense physical exertion;
- after operations and various diseases;
- diseases accompanied by a lack of carnitine, as well as its increased loss;
- strong and persistent muscle cramps;
- general weakness affecting the quality of life;
- muscle weakness or myopathy;
- cardiomyopathies;
- anemia requiring large doses of erythropoietin;
- psoriasis, seborrheic eczema, scleroderma, discoid lupus erythematosus.
Prohibitions on the use of solution
Are there any contraindications for the Almiba medicine? The instruction attached to the drug states that this tool can not be used only with hypersensitivity to its components. In other cases, this medication is not contraindicated.
The drug "Almiba": instructions for use
The price of the product in question is not very high.
This medication can be administered intravenously or intramuscularly. In the first case, it is poured slowly in a stream or drip. The contents of the ampoule are dissolved with a 0.9% solution of sodium chloride in an amount of 100-190 ml.
The dosage and duration of treatment with this agent are set individually (depending on the indications).
The daily dose of medication for adolescents from 12 years old and adults is 1-3 g in 3 injections.
For children under the age of 12 years, the treatment regimen is determined taking into account the patient's body weight.
In cases of acute cerebrovascular accident, the medication is prescribed in an amount of 1 g per day for 3 days, and then 0.5 g for a week.
After 10-13 days, the course of treatment can be repeated.
In the recovery and subacute periods, as well as with brain damage and dyscirculatory encephalopathy, the solution is administered to patients at the rate of 0.5-1 g per day intravenously or intramuscularly (in 3 administrations).
With a post-infarction condition and angina pectoris, the medication in question is prescribed orally in a daily dose of 2-6 g. Before such a medication, the contents of the vial are dissolved in a glass of water and taken regardless of food intake.
With congenital metabolic disorders, the dosage of the drug depends on the specificity of the pathology, as well as its clinical severity during treatment.
The duration of parenteral therapy with this drug should be at least 3 months, since it is during this period that the normal level of free carnitine in the muscles is restored.
The therapeutic efficacy of the drug should be evaluated by monitoring indicators of plasma levels of free and acylated carnitine, as well as by studying the dynamics of clinical symptoms.
Side effects
Almiba medicine, the instruction for use of which was presented above, very rarely causes negative consequences. Due to the increased level of released energy during the treatment with this drug, the patient may develop insomnia. To prevent this, the patient should take L-carnitine before lunch.
With individual carnitine intolerance, a person may experience nausea, headache, or stool disturbance.
Special information
With high glucose utilization, the administration of the drug in question to diabetic patients during hypoglycemic oral therapy or insulin can easily increase hypoglycemia.
The efficacy and safety of oral levocarnitine treatment cannot be evaluated in people with renal failure. The prolonged use of high doses of such a drug for kidney diseases during hemodialysis can lead to the accumulation of trimethylamine, toxic metabolites and trimethylamine n-oxide, since they are excreted in the urine. Similar cases are absent with intramuscular or intravenous infusion of levocarnitine.
Price, reviews, analogues of the drug
Now you have an idea of what Almiba is. Instructions for use, price, reviews about this medicine are indicated in this article.
The cost of this drug is approximately 150 rubles. If required, it can be replaced with such medicines as Aghvantar, Karniel, Karnivit, Karniten, Steel, Lecarnita, Heptral, Gepadif, Stimol.
As for consumer reviews, there are not very many of them. From the reports that are available, we can safely conclude that the drug in question is a very effective and efficient metabolic agent.
The advantages of this medicine include the fact that it can be used not only for adults, but also for newborns. The main thing in this case is to observe all dosages prescribed by the doctor, as well as apply the most suitable method of drug administration.
It should also be noted that in case of urgent need, this medication can be prescribed to pregnant and lactating women. However, in this case, you should always consult a doctor and study the attached instructions.