The drug "Orvirem" (for children) is available in the form of a suspension. The active ingredient is rimantadine. The medication is often prescribed in pediatrics. The drug "Orvirem" is very effective as a preventive and therapeutic agent during the spread of infection in groups, in contact with patients, and also with a high probability of developing the disease against the background of the epidemic. The tool has a pronounced activity against influenza A virus and negligible activity against influenza B.
It should be noted that, relatively recently, the use of drugs including rimantadine has been strictly limited by age. However, employees of the Research Institute of Influenza and other departments of the Russian Academy of Medical Sciences have developed a new medicine based on the polymer form of the active component - Orvirem.
The composition of the medicine includes low molecular weight modified sodium alginate, which has detoxification and absorbing properties. The active component of the agent is fixed on its matrix. Sodium alginate circulates through the blood ten times longer than rimantadine (the active substance). In this case, the diffusion rate of the first is significantly reduced. With prolonged (prolonged) circulation, rimantadine (in this dosage form) is released gradually. The active component selectively interacts with the transmembrane protein of the virus, disrupting some of its functions.
All this allows you to reduce the dose and, therefore, the likelihood of negative effects, thus ensuring good tolerance.
Describing the medicine "Orvirem" (syrup), the instruction indicates its ability to influence the cause of the disease, destroying influenza viruses. The drug acts quite quickly and effectively, is well tolerated by patients in childhood. The undoubted advantage of the drug "Orvirem" experts consider the ability to use it not only for treatment, but also for prevention.
The drug "Orvirem" instruction recommends use for the treatment and prevention of acute respiratory viral infections and influenza in children aged one to seven years.
To prevent the development of viral diseases, twenty milligrams are prescribed for children under three years old, and from three years old - thirty milligrams. Take the medicine once a day.
For treatment, the drug "Orvirem" instruction recommends prescribing to children under three years of age in the amount of twenty milligrams at a time. On the first day, take three times, on the second and third - twice, from the fourth day they switch to a single dose per day. Children from three years old only increase the dosage (up to thirty milligrams). The regimen remains unchanged.
The duration of treatment is from ten to fifteen days.
The dose per day of the drug "Orvire" should not be more than five milligrams per kilogram of mass.
The tool should be taken after meals, washed down with water.
In clinical practice, cases of overdose are not recorded.
Side effects of the drug "Orvirem" include rashes, hives, itching and other allergic reactions. In addition, taking the drug can provoke neurotic disorders, disorders in concentration, anorexia, dizziness, abdominal pain, headaches, vomiting, or nausea.
Medication "Orvirem" the instruction does not allow for the appointment of patients with diabetes mellitus, thyrotoxicosis, with acute or chronic pathologies of the liver and kidneys, children up to a year. The drug is contraindicated during the entire period of gestation and lactation. Do not prescribe a remedy for individual sensitivity.
Before using the suspension, you need to consult a pediatrician, carefully study the annotation.