Nise is a non-steroidal anti-inflammatory drug. It is quite potent, so when using it is necessary to follow the instructions. How compatible "Nise" and alcohol will look at in this article.
Description of the drug
Available in the following forms:
- in the form of a suspension;
- in gel form;
- in the form of tablets.
The list of indications for the tablet form is universal, therefore it is precisely they most often can be found in home medicine chests.
Nise has the following properties:
- anti-inflammatory;
- antipyretic;
- painkiller (headache, muscle, toothache, menstrual pain stop).
Are Nise compatible with alcohol? About it further.
The main active ingredient is nimesulide. Most often used for diseases of the musculoskeletal system (arthrosis, arthritis, rheumatism, neuralgia). Sprains and inflammation of the ligaments and tendons, postoperative pain are also indications for use.
The drug has structural analogues. Nise and alcohol affect the body about the same.
When ingested, nimesulide acts as follows:
- the synthesis of hormones-mediators of prostaglandins is suppressed (they give pain);
- platelet aggregation (gluing) is inhibited, that is, blood is diluted;
- toxins are not formed, that is, an antioxidant effect is manifested;
- glucocorticoid receptors are activated, an anti-inflammatory effect is manifested in this.
How do Nise and alcohol interact?
The analgesic effect of the drug occurs very quickly, after about 5-10 minutes. The maximum concentration of a substance in the blood 2 hours after administration. 3-5 hours is required for the half-life of the main metabolite. The kidneys and bile remove the substance from the body.
Metabolism occurs primarily in the liver. His action is hepatotoxic. For diseases of this organ, it is not recommended for use. Prolonged use should be careful. The gastric mucosa is negatively affected. Often in the form of side effects, gastrointestinal diseases develop. Also, the instructions for use indicate that “Nise” depresses the central nervous system, causing drowsiness and some slowdown of all reactions. Drivers and those who work with mechanisms should use the medicine with great care.
Can Nise and alcohol be combined? This question interests many.
Since alcohol also has a toxic effect on the liver, kidneys, stomach, central nervous system, when taken with Nise, the negative effect is amplified several times. Specialists confirm the complete incompatibility of alcohol and Nise.
What consequences can this lead to?
With the simultaneous use of the drug and alcoholic beverages, the following negative consequences may develop:
- From the liver. It has a double effect on the liver of toxins (drug and alcohol). There is a lack of enzymes that break down poisons. As a result, they remain in the body, poisoning it. Especially in the presence of cirrhosis and other diseases of this organ.
- Gastrointestinal tract. Alcohol and Nise, taken concurrently, cause heartburn, abdominal pain, nausea, and vomiting. With excessive drinking, poisoning of the body occurs, “Nise” reinforces this reaction.
- Heart and blood vessels. Under the influence of alcohol, the vessels expand, from “Nyza” blood coagulation decreases. This can cause internal bleeding, especially if there is a stomach or intestinal ulcer.
This combination also harms the kidneys, since they remove so many toxins. Ethanol and nimesulide act the same way on the central nervous system, so inhibition, poor reaction, drowsiness only increase. After all, Nise and alcohol are incompatible. After how long can I take medicine or drink alcohol? About it below.
How to combine alcohol and Nise tablets?
We found that this medicine and alcohol are incompatible. To avoid serious health consequences, you must wait until the active substance or alcohol is excreted from the body.
There are some rules for using the drug:
- It is necessary to take into account the time of alcohol removal from the body. It depends on the weight of the person and the strength of the drink. The average is 6-12 hours. You can take Nise after this time. The drug is not categorically suitable for the treatment of a hangover.
- About 5 hours after the Nise tablet is drunk, it will not remain in the body. That is, by this time you can start drinking alcohol.
- If “Nise” is prescribed for the course and there is no way to interrupt it, then some time before the feast you can drink a capsule of the drug “Omeprazole” or any analogue of it: the gastric mucosa will be more protected. But before that, you need to get advice from your doctor. Any drug should be taken deliberately.
Main conclusions
So, a joint intake of Nise and alcohol is not recommended. Especially with prolonged therapy with non-steroidal anti-inflammatory drugs. After all, the liver and kidneys suffer with regular intake of Nise. It can also lead to ulcers and erosion of the mucous membrane of the stomach or intestines. Internal bleeding is not ruled out. Therefore, with the mind you need to combine "Nise" and alcohol. How much can I take this or that?
Be sure to observe the time interval when using the drug and alcohol. If the doctor has prescribed long-term treatment of NSAIDs, then it is necessary to undergo comprehensive examinations of the whole body in order to prevent the development of dangerous complications. Chronic diseases can worsen even after a single dose of alcohol.
Conclusion
One's own health cannot be taken too lightly. In some cases, when, for example, the head hurts slightly or the stomach aches, it is better to endure the discomfort. Lie down, take a nap or take a walk in the fresh air than drink Nise tablets and alcohol. Uncontrolled intake of anti-inflammatory and analgesic drugs is unacceptable. Especially with the joint use of alcohol.