Bronchitis is a disease in which inflammation of the mucous membrane of the bronchi is observed. The disease must be treated with the medication method. If the disease has a bacterial nature or inflammation is severe, doctors prescribe antibiotics. This drug is considered "Azithromycin." With bronchitis, this medicine is effective, both for adults and for children.
pharmachologic effect
"Azithromycin" is a drug with a wide spectrum of action, it is part of the macrolide group. The drug is effective in the treatment of infectious ailments of an inflammatory nature. The medication is able to accumulate in the area of inflammation in concentrated doses, it has a strong bactericidal effect.
Due to the high concentration of active components in the site of inflammation (in the bronchi), the production of foreign proteins by pathogens ceases, and the process of their reproduction is also reduced. After taking the drug, the active components enter the blood vessels to the lungs and enter the tissues. The medication penetrates the pulmonary parenchyma and bronchi, so pathogenic microorganisms cannot enhance inflammation.
When localized in the area of inflammation, therapeutic substances inhibit inflammation, therefore, "Azithromycin" in bronchitis is used for adults and children. The drug acts after 2 hours, excretion from the body is carried out for a long period.
The drug is excreted 2 days after administration and only half. It is undesirable to take the drug for more than 5 days in a row, this course of therapy is considered optimal in the treatment of the disease. According to reviews, "Azithromycin" for bronchitis, adults and children should be used after consulting a doctor. This is due to the fact that the drug is considered an antibiotic.
Pharmacokinetic effect
"Azithromycin" for bronchitis should be taken on an empty stomach, that is, between meals. This is due to the fact that if the drug is taken on a full stomach, then the effectiveness of the substances decreases many times. In addition, this drug will not be rapidly absorbed into the bloodstream, and it will also easily enter the affected organs.
The medication is resistant to the gastric environment and accumulation in tissues, and in the blood plasma it does not settle. With the accumulation of active substances in leukocytes, the antibacterial effect of the agent will be stronger. With other therapeutic drugs of this category, “Azithromycin” is able to be excreted within 3-4 days, medications are excreted unchanged. Due to prolonged withdrawal, the antibiotic helps with bronchitis.
When is it used?
"Azithromycin" is used in the treatment of bacterial diseases that develop from harmful microorganisms. The drug quickly and effectively suppresses pathogenic activity. The drug is considered a macrolide and has an antibacterial effect. Effective for bronchitis "Azithromycin" if the disease appeared from:
- chlamydia;
- pneumococci;
- mycoplasmas;
- legionella;
- moraxella.
If the disease appeared from staphylococcus aureus or enterococcal infection, then the treatment will not be effective. These bacteria are immune to the drug, so therapy does not bring results.
If the disease appeared from staphylococci or enterococci, then treatment should be carried out with the help of semi-synthetic antibiotics. Before treatment, it is necessary to determine the strain of bacteria that led to the disease, perform bacteriosis of sputum, establish the sensitivity of organisms to the drug.
Forms of the drug
According to reviews, "Azithromycin" for bronchitis is sold in every pharmacy. In this case, the tool is available in several forms:
- Suspensions They are available in a dosage of 100 ml and 200 ml. The body of children is the most sensitive and undeveloped, so a lower dosage is needed. They are prescribed a remedy in this form.
- Powder. From it create suspensions. From 5 ml of powder, 200 ml is obtained. suspension, which can be used in the form of an injection or orally.
- Capsules They have a gelatin base. Capsules are available in 250, 500 and 600 mg.
The form of the drug is chosen by the doctor based on the individual characteristics of the patient. "Azithromycin" for bronchitis in adults and children is effective, you only need to follow the treatment recommendations provided by a specialist.
Dosage
Which dosage to choose? How to take "Azithromycin" for bronchitis? With acute or chronic bronchitis, adults need to take the drug for 5 days 2 hours before a meal. On 1 day of treatment, 1 tablet of 500 mg is required. Then, 1 tablet of 250 mg is required. According to reviews, "Azithromycin" with bronchitis 500 mg is considered effective.
In the treatment of illness in children, this remedy is also used, but after 1 year and consultation with a pediatrician. Therapy for children 1-12 years old is performed as follows:
- On the 1st day of treatment, take 1 time - 10 mg per 1 kg of weight.
- The next 4 days are required to be given 1 time per day - 5 mg per 1 kg of weight.
It is advisable to take the medication in the morning, taking into account the following recommendations:
- During treatment of bronchitis in children, the dosage should be no more than 30 mg per 1 kg of weight.
- In children from 12 years of age, the dosage can be increased to 250 mg.
- In the treatment of bronchitis in infants, whose weight is less than 5 kg, the drug is not used.
- The maximum course of therapy is 7 days.
- In acute bronchitis, treatment can be extended for another 1 week.
- In order for the treatment of chronic bronchitis to be effective, antimicrobial medicines are taken with an antibiotic that stimulate the immune system. These include “Immunal” or tincture of “Echinacea”.
- If the improvement is not noticeable on day 14, then you need to change the drug.
It is important to adhere to the dosages recommended by your doctor. This will prevent adverse effects on your health.
Treatment recommendations
Like other antibiotics, Azithromycin can not only help, but also cause harm. To minimize the negative impact, it is necessary to adhere to the rules for the use of "Azithromycin" in bronchitis:
- During treatment, you can not drink alcohol.
- Do not take medicine for people with kidney or liver problems, as well as mental disorders.
- Medicines must be taken at the same time. If you skip taking them, you should immediately use them. The following procedure should be carried out after the designated time.
- Joint administration with alkaloids leads to ergotism.
- When combined with "Disopyramide", "Rifabutin", "Lovastatin", "Digitoxin" unpleasant side effects appear.
Subject to these rules, it will be possible not only to recover from bronchitis, but also to prevent the appearance of pathological complications. The course of therapy with this tool must be taken under the supervision of a doctor.
Features of the reception
"Azithromycin" should be taken once a day, regardless of food intake. If there is an upset stomach, the antibiotic is taken with food. Features of the treatment are as follows:
- You should not interrupt the course, you need to continue therapy, even if the symptoms have been eliminated earlier.
- If the therapy is completed ahead of schedule, then the infection may become chronic.
A general blood test, with which the nature of the infection is different, is performed in a hospital. Pediatricians and therapists often do not take them into account, prescribing antibacterial agents if wheezing is heard.
Many acute bronchitis are not caused by bacteria, so antibiotics are not required. The problem of treatment is that the viral form disappears on its own as the body's immune forces are activated, and the bacterial form is inhibited by the drug.
special instructions
Take “Azithromycin” continuously for at least 3 days, taking into account the dosage. Caution should be taken in case of impaired liver and kidney function. When taken together with antacid medicines for the treatment of gastrointestinal diseases, you need to drink "Azithromycin", and then after 2 hours - "Antacid".
You can not take medication during pregnancy. During lactation, it is also undesirable to use it. During the course of therapy, it is important to observe precautionary rules for drivers of transport and employees of areas where a quick reaction is needed, since the drug can lead to dizziness and other disorders of the nervous system.
Contraindications and side effects
As indicated in the instructions "Azithromycin", with bronchitis medication can not be used for such phenomena:
- intolerance to the components;
- allergies to macrolide antibiotics.
In other cases, the drug can be taken. As evidenced by numerous reviews, the antibiotic acts positively and does not have serious side effects. But sometimes the appearance is still likely:
- heart palpitations;
- dizziness and headaches;
- Depression
- urticaria;
- diarrhea
- chest pain
- apathy;
- loss of taste;
- nausea
- stool disorders;
- vaginitis.
These conditions are rare. They occur in the elderly and in people with a weak immune system. Antibiotic treatment in patients with bronchitis, especially in the elderly, should be under the supervision of a physician.
Interaction
"Azithromycin" can interact with various means. It will have a stronger activity if combined with tetracycline and chloramphenicol. And with lincosamides, the effect of this drug is weakened. Antibiotic absorption will be delayed when antacids and ethyl alcohol are taken concomitantly.
When the reaction of microsomal oxidation in the liver is slowed down, Azithromycin enhances the toxic properties of dihydroergotamine, carbamazepine, xanthines, and hypoglycemic agents. The drug increases the plasma concentration of indirect anticoagulants and cycloserine.
The drug is used for antibiotic therapy of respiratory ailments. It is effective for adults and children in dosages prescribed by a doctor. The course of treatment is short, which eliminates negative health effects, increases patient adherence to treatment and reduces costs.
Analogs
Sometimes doctors prescribe similar drugs. Instead of "Azithromycin" the following is allowed:
- "Sumazid."
- "Zitrocin."
- "Sumamed."
- "Azithrala."
- "Summamox."
- Sumameda Forte.
- "Azitrox".
The main substance in these medicines is azithromycin. But the price may be different, it all depends on the manufacturer. What is better with bronchitis - “Azithromycin” or “Amoxicillin”, the expert will tell. In the second drug, amoxicillin is considered to be the active ingredient, which is active against bacteria that synthesize beta-lactamase. Both are considered safe and effective, but they should still be prescribed by a doctor.