In this article, we consider the instructions and price of Fromilide Uno 500 mg. In modern medicine, antibiotics are widely distributed, which are among the macrolidodes, since, according to experts, they are the most effective and safe among antibiotics. In addition, in accordance with many scientific studies, they have very few contraindications compared to other groups of antimicrobials.
Until recently, the most frequently used drug of this series was Erythromycin, however, modern pharmacological developments have appeared at present, among which the semi-synthetic drug Fromilide, as well as its prolonged version Fromilide Uno, has gained popularity. He received many positive reviews from patients and doctors.
General points
Among all macrolides, this drug, the mechanism of action of which during use is determined by the main component - clarithromycin, satisfies to the maximum extent all the requirements for antibiotics. Such drugs as Fromilide Uno and Fromilide are among the newest in this group, are called "new macrolides", and are widely used in the treatment of various infectious diseases, including bacterial prostatitis. The first drug is in the form of tablets that can be taken on an outpatient basis.
The price of Fromilide Uno 500 mg is of interest to many who need this medication.
The absolute advantages of the drug are:
- high bioavailability;
- a single dose per day;
- proven effectiveness;
- the optimal ratio of concentration in the blood and tissues;
- high ability to concentrate at the cellular level;
- extensive spectrum of action;
- significant activity of the main active ingredient;
- high degree of security;
- the drug is well tolerated by patients.
Structure
The active ingredient clarithromycin with a release of a prolonged type is available in tablets in the amount of 500 milligrams. "Frolimid Uno" prolonged form allows you to use it once a day, since the slow and gradual penetration of the drug into the blood makes it possible to ensure the constant presence of the drug in the inflamed organ. In addition, the medication penetrates well and for a long time retains an increased concentration in the immune system. This is especially important, for example, when using chronic and acute forms of prostatitis as an antibacterial treatment. In addition to antibacterial properties, the drug also has a sign of immunotropic activity, has a pronounced effectiveness in inflammation.
When is it prescribed?
Instructions for use "Fromilid Uno" prescribes to be taken most often with infectious pathologies of the respiratory system. However, the effectiveness of the main active ingredient is superior to both macrolide analogues, and 1st and 2nd generation cephalosporin antibiotics, and unprotected penicillins.
The high effectiveness and prolonged effect of Fromilide Uno allows its use in the treatment of other diseases of an infectious nature, including also prostatitis. The drug is significantly effective in the fight against staphylococcus, hemophilus bacillus and pneumococcus, in some ways superior to the use of such popular antibacterial agents as Roxithromycin, Cefaclor and Amoxicillin.
Among the other therapeutic characteristics of the drug, it is also worth noting its post-antibiotic effect, which means the ability of the drug to inhibit the functioning of pathogenic microorganisms at the end of its administration.
“Fromilid Uno” is produced in Slovenia. There are such forms of release as tablets (or 250, or 500 mg), and suspension (volume - 125 mg).
Many are interested in the cost of the medicine.
Cost
Its cost is quite affordable. The price of Fromilid Uno (500 mg) is about five hundred rubles, 250 mg each - about 320 rubles.
Indications for use
In the instructions for use of the drug, it is recommended to use it for various kinds of diseases of bacterial origin, if the pathogenic flora is sensitive to the drug. First of all, these are the following indications:
- bacterial inflammation of the lower respiratory tract - bronchitis, including also the chronic type, various types of bacterial pneumonia;
- infectious diseases of the upper respiratory system - chronic and acute varieties of otitis media, sinusitis and tonsillopharyngitis;
- skin infections (erysipelas, folliculitis).
As a means of complex treatment, it is used for peptic ulcer and duodenal ulcers to eliminate Helicobacter pylori and bacterial prostatitis, as well as for other diseases.
The duration of the treatment course is established by a specialist who treats a specific patient.
In the instructions for use, it is recommended to prescribe “Fromilide Uno” at the outpatient stage of therapy for bacterial inflammation of the lower and upper respiratory tract, including the atypical type of pneumonia, tonsillitis, asthmatic diseases caused by atypical bacteria, as well as other indications.
For patients under twelve years of age, the drug should be prescribed in the form of a suspension, which is one of the forms of the drug. The suspension consists of a dose of 125 mg. The medicine as a whole receives good reviews from pediatricians. The price of “Fromilida Uno” basically suits patients.
Contraindications
The medication has the following contraindications:
- high sensitivity of the patient to antibiotics of this group or, in particular, to clarithromycin;
- the presence in the patient’s history of the disease of complex forms of renal failure (with creatinine clearance of less than 30 ml per minute);
- lactose intolerance to the patient;
- pregnant women in the first trimester, as well as during breastfeeding;
- it is forbidden to take ergot alkaloids along with all;
- if the patient has a history of cholestatic jaundice;
- in the form of a suspension is prohibited for the treatment of children under six months of age, since no studies have been conducted regarding the safety of its use;
- Until the age of twelve, children are undesirable to take pills, however, you can drink a suspension.
Side effects of using the medication
According to reviews, Fromilid Uno (500 mg) and its analogues, like any antibiotic in this group, can cause a number of certain side effects from various systems and organs:
- Digestive system: vomiting, nausea, dyspepsia, diarrhea.
- Epidermis: rash, excessive sweating, itching.
- Nervous system: drowsiness, headaches, anxiety.
- The system of the heart and blood vessels: in some cases, tachycardia.
Allergy to this drug
Sometimes, side effects may occur when using “Fromilid Uno” (500 mg) in the form of allergic reactions to the main active ingredient or to any substances in the composition of the drug. When prescribing the drug, the specialist should warn the patient that it is necessary to completely refrain from drinking alcohol during the treatment course. Alcohol, in addition to a direct effect on the metabolism of antibiotics, can cause serious liver pathologies during a chemical reaction with them and in especially serious cases even lead to the death of the patient. Therefore, it is not surprising that the condition of the liver is very deplorable after it is affected by alcohol in combination with antibiotics.
In addition to excluding alcohol, during treatment, hepatoprotectors, which are desirable to use along with antibiotics, are prescribed to protect the liver from negative influences. Reviews of patients and doctors are generally positive, side effects are quite rare and immediately disappear after discontinuation.
The price of Fromilid Uno was presented above.
Analogues of this medication
The product has quite a few analogues that are widely represented in the pharmaceutical market. The closest in composition - the drug "Klacid", also based on clarithromycin and having the same indications for use.
The instruction for the drug recommends writing out this analogue of Fromilide Uno in the same cases. The drug is produced in the United States in the form of tablets with a dosage of 250, 125 and 500 mg, and also as a powder used to make the suspension. A package containing ten tablets of 250 mg on average costs 700 rubles. Such a high cost does not allow this tool to fully compete with the described drug, although its effectiveness is confirmed in many reviews.
If there is an individual intolerance to the drug, then you can replace it with another Fromilid Uno analogue 500 mg - the Flemoxin antibiotic, which differs in composition, as it is among penicillins, however, it has similar indications, and the difference is only in the active component . This tool is cheaper than other analogues, it is also forbidden to use with alcohol.
Interaction with other drugs
In the instructions for the drug, special attention is paid to its compatibility with other drugs. For example, if a patient drinks anticoagulants, for example, Warfarin, it is necessary to constantly monitor the functioning of the liver. Low compatibility with ergot alkaloids is also noted. If it is impossible to cancel these drugs, you should always monitor their concentration in the blood.
Reviews of Fromilide Uno
At this point, close attention should be paid. Currently, macrolide antibiotics such as Fromilide and the prolonged form Fromilid Uno with analogues have earned positive opinions from patients and doctors, including when used to treat children. The undoubted advantage of the drug is its ability to combat various types of pathogenic microorganisms, as well as a wide range of indications for use. This is an excellent generic that combines high quality and affordable cost. Effective as a monotherapy for infections of the upper respiratory tract, and in combination with other drugs in the treatment of pneumonia. It is often prescribed by doctors, because it really has a noticeable effect. Like all antibiotics, it requires concurrent administration of probiotics.
Negative comments
Negative reviews about Fromilide Uno are mainly associated with a bitter taste, as this in some cases complicates the intake, especially in the treatment of children. In addition, the presence in the body of the molecule of the active substance in some patients causes bitterness in the mouth, accompanied by nausea. A similar side effect is not a manifestation of liver damage with the drug, but the appearance of unpleasant sensations stops the patient from undergoing the full course of treatment with this drug. In some people, Fromilide Uno helps stimulate motility and eliminates intestinal contents, and diarrhea appears. The resistance of many microorganisms to this drug is noted, especially when previously using clarithromycin or other macrolides. Young patients do not like the taste of the medicine. In some cases, it can cause nausea and a feeling of heaviness in the stomach.
But still, this is a worthy preparation from a good manufacturer. The tool is effective along with standard clarithromycin. It is fairly well tolerated, allergic manifestations are rare. It is used to treat both adults and children. The use mode is quite convenient.