The drug "Puregon" describes the instructions as a means of stimulating the maturation of the follicle. Being a recombinant human follicle-stimulating hormone, it stimulates ovulation and promotes pregnancy. Follitropin beta - the active substance of the drug.
A drug is produced in the form of a lyophilisate, which is used to prepare a solution for intramuscular and subcutaneous injections.
Puregon enters the pharmacy network as a ready-made solution for injection (900 IU / 1.08 milliliters) and is a kind of injection cartridge, which is complemented by a set of nine needles.
It is possible to use the Puregon preparation only as prescribed by the doctor, therefore, its purchase in pharmacies is possible only by prescription.
The doctor may consider the following indications as the basis for prescribing the drug:
- female infertility, which is caused by hypothalamic-pituitary disorders;
- polycystic ovary syndrome ;
- lack of ovulation ;
- stimulation of superovulation (when using IVF technology).
Before a woman will be stimulated with Puregon, a thorough examination of her body for diseases of the endocrine system (thyroid gland, adrenal gland or pituitary gland) should be carried out.
Also, stimulation of ovulation with the help of such drugs can significantly increase the risk of multiple pregnancy. With this form of pregnancy, the risk of complications increases, both during pregnancy and in the perinatal period. In order to prevent the development of multiple follicles, appropriate dose adjustment of follicle-stimulating hormones is required.
Therefore, before starting such a procedure as stimulation of ovulation with a puregon of a patient, it is necessary to warn that a multiple pregnancy may occur as a result of it .
However, stimulating ovulation helps many women to have a welcome baby. However, not every patient who needs stimulation is shown the use of such drugs as Puregon, the instructions for its use contain detailed information about contraindications.
The use of the drug is contraindicated in the presence of the following ailments and disorders in a woman:
- various types of tumors (ovaries, mammary gland, uterus, pituitary gland and hypothalamus);
- bleeding, both vaginal and uterine;
- primary ovarian failure;
- cyst or ovarian enlargement ;
- improper anatomy of the genitals, which makes it incompatible with pregnancy;
- uterine fibroids;
- pathology of the endocrine system (thyroid gland, adrenal glands, pituitary gland);
- violation of the liver and kidneys;
- pregnancy period;
- period of breastfeeding;
- intolerance to any component of the drug.
In addition to information about contraindications to the use of the drug "Puregon", the instruction contains information about the side effects that this drug is capable of exerting.
Side effects can include phenomena such as lower abdominal pain, nausea, diarrhea, ovarian cysts, thromboembolism, hypotension - all these are signs of ovarian hyperstimulation syndrome, and multiple or ectopic pregnancy may occur. There are frequent cases of fever, pain in the mammary glands, skin rash, urticaria.
But the most important information provided by the Puregon preparation is the instructions for use, however, is its dosage regimen. However, due to the fact that the drug is not recommended for independent use, we will not consider this information in this article.
Keep the drug in a place that is inaccessible to children and protected from direct sunlight for no more than three years. The temperature in the room should not exceed eight degrees, but it is not recommended to freeze the drug.