Very often, experts prescribe a drug such as Sedalgin Neo to their patients. Instructions for use of this drug will be presented in the materials of this article. We will also tell you about the form in which this medication goes to the pharmacy, what its composition is, how much it costs, whether it has side effects, contraindications and what it is intended for.
The drug "Sedalgin Neo": composition and form of release
Currently, the drug we are considering is on sale only in the form of round white tablets. The therapeutic effect that is observed after taking the medication is due to its composition.
One Sedalgin Neo tablet contains 10 mg of codeine phosphate, 15 mg of phenobarbital, 50 mg of caffeine, 150 mg of metamizole sodium and 300 mg of paracetamol.
You can buy this tool in a cardboard box, in which there are 10 tablets in a blister.
Pharmacological characteristics of the drug
What is the medicine "Sedalgin Neo"? The instruction, enclosed in a cardboard box along with the medicine, contains information that it is a combined preparation that can have vasodilating, analgesic, antipyretic and anti-migraine effects. Also, the remedy considered by us easily eliminates the symptoms of flu and the common cold.
Details on the composition of the drug
As mentioned above, the effectiveness of the drug Sedalgin Neo, whose price is not very high, is due to the combination of substances that make up its composition. Consider the mechanism of action of each element in more detail.
- Codeine , which is part of the medication, has a central antitussive effect. This happens due to the suppression of the excessive excitability of the cough center. Codeine also contributes to the analgesic effect, which is caused by the excitation of opiate receptors in different parts of the nervous system, which ultimately leads to stimulation of antinociceptive systems and a change in the emotional perception of the pain syndrome. It is impossible not to say that codeine, to a lesser extent than morphine, is able to inhibit breathing, cause vomiting, miosis, nausea and constipation (activation of opioid receptors in the intestine causes relaxation of their smooth muscles, as well as a decrease in peristalsis and spasms of all sphincters). This element enhances the effect of analgesics.
- Caffeine has an analeptic effect, and also stimulates the psychomotor centers of the brain (brain). Also, this element is able to enhance the effect of analgesics, eliminate the feeling of fatigue and drowsiness. In addition, taking caffeine as part of the drug significantly increases mental and physical performance.
- Paracetamol is an analgesic (non-narcotic). It blocks cyclooxygenase-2 and cyclooxygenase-1 (mainly in the central nervous system). It is impossible not to say that this particular element acts on the centers of thermoregulation and pain, and also has antipyretic and analgesic effects.
- Metamizole is an anti-inflammatory non-steroidal substance. It is able to have an antipyretic, analgesic and antispasmodic effect on the smooth muscles of the biliary and urinary tract.
- Phenobarbital is called an antiepileptic drug that is capable of exerting sleeping pills, sedatives, muscle relaxants and antispasmodics on the human body.
How long does the Sedalgin Neo preparation work, the composition of which is presented above? The duration of action of this medication is 4-6 hours (after taking one tablet).
Indications for the use of a medical device
Sedalgin Neo tablets are prescribed for moderate and low intensity pain. The drug significantly alleviates the condition of patients who have one of the following deviations:
- febrile syndrome, including the development of acute respiratory viral infections;
- arthralgia;
- pain with burns and other injuries;
- myalgia;
- algodismenorea;
- migraine;
- neuralgia;
- head and dental pain syndromes;
- sciatica;
Contraindications to the use of a medical device
Can I use Sedalgin Neo without a prescription? Of course.
However, before taking it, you should definitely read the instructions. This is due primarily to the fact that this medicine has a fairly wide list of contraindications, which everyone should know about. Consider this list right now:
- acute myocardial infarction;
- hypersensitivity to the elements that are part of the drug;
- children's age (up to 12 years).
- severe renal and / or liver failure;
- breast-feeding;
- glucose-6-phosphate dehydrogenase deficiency;
- the time of gestation;
- anemia;
- leukopenia;
- glaucoma;
- bronchial asthma;
- alcohol intoxication;
- conditions that are accompanied by respiratory depression;
- arrhythmia;
- intracranial hypertension.
Cautious medication
The drug "Sedalgin Neo" should be taken with extreme caution in elderly patients and those who have ulcerative lesions of the stomach or duodenum (especially in the stage of exacerbation of the disease), as well as arterial hypertension.
Medication "Sedalgin Neo": instructions for use
Use the drug we are considering only after consulting a specialist or after carefully reading the instructions.
It is recommended to take this remedy by mouth in one tablet. If the pain syndrome has a pronounced intensity, then the frequency of taking the medication can be increased to 4 tablets per day. The maximum single dosage is 2 tablets. On the day, the drug can be taken no more than 6 pieces.
The duration of therapy with the drug "Sedalgin Neo" is 5 days (no longer).
Overdose cases
The increased volumes of the medicine "Sedalgin Neo" can easily lead to an overdose. As practice shows, its symptoms are arrhythmia, nausea, gastralgia, vomiting, depression of the respiratory center and tachycardia.
What to do in case of overdose? The patient should rinse the stomach urgently, as well as prescribe intestinal adsorbents and symptomatic treatment.
Side effects of taking the drug
What side effects are observed after using Sedalgin Neo? As a rule, these are allergic reactions in the form of a rash, itching and urticaria. In addition, the patient may experience drowsiness, tachycardia, dizziness, granulocytopenia, vomiting, decreased rate of psychomotor reactions, constipation, palpitations, leukopenia, nausea, and agranulocytosis.
With uncontrolled and prolonged use of the drug in high doses, it is addictive and drug addiction. In other words, the analgesic effect is significantly attenuated. Renal and liver function may also be impaired.
Interactions with Other Medicines
With the simultaneous use of drugs that inhibit the nervous system (including sedatives and anxiolytics), there is a possibility of increasing the severity of sedative properties and inhibitory effects on the respiratory center.
Sedalgin Neo medication enhances the effect of alcohol on psychomotor reactions.
Oral contraceptives, tricyclic antidepressants and allopurinol can disrupt the metabolism of metamizole in the liver, as well as increase its toxicity.
Metamizole lowers the concentration of cyclosporine. Oral hypoglycemic drugs, corticosteroids, indirect anticoagulants and indomethacin increase its activity.
Phenylbutazone, barbiturates and other inducers of enzymes (microsomal) of the liver can weaken the effect of metamizole.
The simultaneous administration of the drug with other non-narcotic analgesics sometimes leads to increased toxic effects.
Lactation and the period of pregnancy
Is it possible to use the drug “Sedalgin Neo” during gestation? Reviews of experts say that this medication is contraindicated for use not only during pregnancy, but also during lactation.
Special instructions for the use of the drug
As mentioned above, this medication should be taken only after a thorough study of the attached instructions or consultation with a specialist.
With prolonged therapy with Sedalgin Neo (longer than one week), monitoring of the functional state of the liver and peripheral blood picture is required.
When taking the medication in question, it should be remembered that the substances that make up it can easily change the results of doping control analyzes of professional athletes.
This medicine makes it difficult to establish the correct diagnosis for the so-called acute abdomen.
Patients who suffer from atopic bronchial asthma and hay fever have a rather high risk of developing various allergic reactions. In this regard, such people should be prescribed the drug with extreme caution.
In the process of drug therapy with Sedalgin Neo, patients must refuse to drink alcohol and other dishes containing ethanol, as well as be extremely careful when driving motor vehicles and engaging in potentially dangerous activities that require good attention and speed of reaction.
The cost of the drug, its analogues
Now you know what Sedalgin Neo is intended for. The price of this drug is relatively low. Therefore, everyone can afford it. In pharmacies, you can buy this medication for only 200 Russian rubles (for 10 tablets).
But what if, for one reason or another, you should in no case be allowed to take Sedalgin Neo? Analogues of this tool are available in each pharmacy. However, before using them, you should also carefully read the attached instructions.
So, the following tablets are the most popular and relatively inexpensive analogues of the Sedalgin Neo medication: Quintalgin, Pentalgin, Pentalgin-MEZ, Santoperalgin, Pentalgin-Nova and Sedal-M. These drugs are dispensed without a prescription from a specialist.
Reviews of doctors and patients
What do experts and patients say about a drug like Sedalgin Neo? In general, their reviews are positive. Both doctors and patients claim that only one tablet taken of the drug can instantly reduce pain. Moreover, according to experts, the analgesic effect of this drug lasts quite a long time.
As for negative expressions, they are often associated with the manifestation of side effects. In this case, it is better to replace the medication with another, safer for health means.