Breast cancer is the second most common cancer diagnosis for women. A malignant tumor occurs in the tissues of the mammary gland and with the development of the disease metastasizes to other organs. In the fight against this ailment in many countries of the world, the effective Ibrans remedy is used, manufactured by the American company Pfizer.
The main active ingredient of the drug is palbocyclib, announced in 2013 as a fundamentally new drug for the fight against metastatic cancer. It is prescribed for the treatment of postmenopausal patients who have not received prior systemic therapy. The effect of this treatment allows you to extend the life of patients without the progression of the disease, which in turn significantly postpones the timing of the use of chemotherapy and hormonal drugs.
Where can Ibrans buy cheaper
Unfortunately, the cost of the described tool can not but upset those who need it. So, in Moscow, the price of Ibrans capsules was set at 257,000 rubles. But in cases where the cost of a vital drug seems unbearable, the site will help you. . It makes it possible to purchase original drugs at distributor prices, as well as generics of expensive drugs, if available on the Indian market.
Note that a generic is several times cheaper, not because it is less effective. It has exactly the same active substance, but at the same time, the costs of the company for development and advertising are not included in its cost, which significantly reduces production costs and, as a result, reduces the retail price of the drug.
Based on the foregoing, it is safe to say that the price set for the generic drug "Ibrans" is not at all a sign of its lack of effectiveness.
Drug use
Part of the Ibrans preparation, palbocyclib is characterized by the ability to block the activity of enzymes called cyclin-dependent kinases (CDKs), which promote cell growth and division. With the development of cancer, their activity leads to the fact that carcinogenic cells begin to divide uncontrollably.
The described agent is used to combat locally advanced or metastatic breast cancer in women. As a rule, it is prescribed in combination with letrozole to patients in postmenopausal women or with fulvestrant - patients with symptoms of pathological progression, manifested after hormonal therapy.
The treatment cycle with Ibrans is 28 days (125 mg of the drug once a day) - the capsules are taken for 3 weeks, after which they take a break for a week. Reception of capsules should be combined with food, and it is better to do it at the same time.
Side effects
During treatment with Ibrans capsules, certain side effects occur. Most often they include:
- the development of neutropenia (low levels of white blood cells fighting infection);
- manifestations of stomatitis;
- anemia;
- increased hair loss - alopecia;
- nausea, digestive upset;
- feeling tired
- increased risk of developing infections.
In connection with the above, the appointment and monitoring of the use of the drug "Ibrans" should be performed only by a specialist with experience in working with antitumor agents.