"Ciprofloxacin-Akos" is an eye drop with antibacterial effect. This is an antibacterial agent of the fluoroquinolone group, which is intended for local use in the ophthalmic field.
Product release form, composition and packaging
Ciprofloxacin-Akos eye drops are made in the form of a clear solution of greenish-yellow or yellowish color.
One milliliter contains three milligrams of ciprofloxacin (in the form of hydrochloride). The following substances act as auxiliary substances: disodium salt of ethylenediaminetetraacetic acid, water d / i, mannitol or mannitol, benzalkonium chloride, glacial acetic acid, sodium acetate, anhydrous or anhydrous.
The release form is five milliliter polyethylene dropper bottles in cardboard packs.
Pharmacology Features
According to the instructions, “Ciprofloxacin-Akos” is an antimicrobial agent, a fluoroquinolone derivative. It functions bactericidal. It inhibits bacterial DNA gyrase (topoisomerases IV and II, which are responsible for the occurrence of chromosomal supercoiling near nuclear RNA, this is necessary for reading hereditary information), disrupts DNA synthesis, bacterial division and growth, and causes obvious morphological changes (including membranes and cell walls) and accelerated destruction of the bacterial cell.
It bactericidal against gram-negative microorganisms during division and dormancy (since it acts not only on DNA gyrase, but also provokes lysis of the cell wall), on gram-positive microorganisms - only in the process of division.
The reduced toxicity to macroorganism cells can be explained by the lack of DNA gyrase in them.
At the same time, against the background of ciprofloxacin, parallel production of resistance to other antibiotics that are not gyrase inhibitors does not occur, which makes the drug highly effective against bacteria that are resistant, for example, to tetracyclines, cephalosporins, penicillins, aminoglycosides and other antibiotics.
The vast majority of staphylococci that are resistant to methicillin are resistant to ciprofloxacin. The resistance of sensitive pathogens develops very slowly, since, on the one hand, there are almost no persistent microorganisms after the influence of ciprofloxacin, on the other hand, there are no enzymes in bacterial cells that inactivate it.
Indications and contraindications
"Ciprofloxacin-Akos" is used for:
- subacute and acute conjunctivitis;
- post- and preoperative prophylaxis of ophthalmic surgical infectious complications;
- blepharoconjunctivitis, blepharitis;
- infectious inflammation of the organs of vision after the penetration of foreign objects or injuries;
- keratoconjunctivitis, keratitis;
- meibomite;
- chronic dacryocystitis;
- a corneal ulcer of a bacterial nature.
The drug is contraindicated:
- with viral keratitis;
- with individual sensitivity to the composition of the drug;
- children up to one year old.
Instruction manual
"Ciprofloxacin-Akos" is used locally, by digging them into the conjunctival sac. If the patient has an eye infection of moderate and mild severity, one or two drops should be instilled into the affected eye every four hours. If the infection is severe, then instillation is carried out every two hours. Frequency of use is reduced as the condition improves. The treatment course lasts from one to two weeks.
With a bacterial ulcer
The use of “Ciprofloxacin-Akos” in case of a bacterial ulcer: the first day - drop by drop every quarter hour for six hours, then every half hour drop by drop until night's sleep; on the second day - drop by drop from morning to night with an interval of an hour; from the third day to the fourteenth - every four hours in the eye drop by drop. If the ulcer does not heal, the treatment course can be continued.
It is necessary to close the bottle after each use. It is forbidden to touch the eye with a pipette tip.
Side effects
Local reactions from ophthalmic drops “Ciprofloxacin-Akos”: allergic reactions, burning, itching, nausea, mild hyperemia and conjunctival tenderness may occur; rarely - photophobia, swelling of the eyelids, lacrimation, an unpleasant aftertaste in the mouth, a foreign object in the eyes, a decrease in visual acuity, the appearance of crystalline white precipitate in patients with corneal ulcers, spots, keratopathy, corneal infiltration, keratitis.
If any of the listed symptoms occurs, you must immediately stop using the drug and consult a doctor.
special instructions
As indicated by the instructions for use, “Ciprofloxacin-Akos” should be carefully prescribed to patients with vascular atherosclerosis of the brain, seizures syndrome and defects in the blood circulation of the brain.
The medication is used exclusively locally. The drug can not be administered directly into the anterior chamber of the eye or subconjunctival.
The patient must be informed that if conjunctival hyperemia increases or continues for a long time after use of the drops, he needs to stop using the drug and consult a specialist.
Contact lenses
It is not advisable to wear contact soft lenses during drug treatment. If hard lenses are used, then you need to remove them before the procedure and put them on again 15-20 minutes after drug administration.
Impact on the ability of patients to control mechanisms and drive a vehicle: people who have lost their clarity of vision after using Ciprofloxacin-Akos are not allowed to work with serious machinery, equipment or machines, or drive a car, because they require clarity of vision immediately after procedures.
Interaction with other drugs
The pharmaceutical interaction is as follows: ciprofloxacin solution is incompatible with such solutions of drugs that have pH values ​​from 3 to 4, unstable chemically or physically. With simultaneous use with other antimicrobial drugs, synergistic interference is usually observed (metronidazole, clindamycin, aminoglycosides, beta-lactam antibiotics).
The instructions for use with Ciprofloxacin-Akos Drops do not indicate analogues. Consider them below.
Analogs
Drops have the following analogues:
- Ear drops and eye drops “Ciprofloxacin-Solofarm” in the form of an almost transparent or transparent, slightly colored liquid.
It is intended for local use: subacute and acute conjunctivitis, meibomites, blepharoconjunctivitis, keratitis, chronic dacryocystitis, blepharitis, keratoconjunctivitis, bacterial corneal ulcers. Infectious inflammation of the eyes after the penetration of foreign objects and injuries. Prevention before surgery in ophthalmosurgery.
When applied topically, 1-2 drops are injected into the affected eye, into the lower sac of the conjunctiva every 1-4 hours. Once the condition improves, the intervals between administrations can be increased.
- Drops "Rotsip" eye transparent, yellow or light yellow.
It is used in the treatment of infections of the anterior segment and appendages of the eye apple, provoked by bacteria sensitive to ciprofloxacin, corneal ulcers in newborns (up to 27 days from birth), infants and babies (from 28 days to 23 months), older children (2-11 years old) ), adolescents (12-18 years old), adults.
When carrying out treatment with ciprofloxacin, the recommendations that are set out in the official instructions for using antibacterial agents should be taken into account.
In case of corneal ulcers, the medicine should be instilled with the following intervals between the procedures (including at night): on the first day every 15 minutes, two drops in the first six hours, then every half hour in two drops for the rest of the day. On the second day of treatment - two drops every hour. From 2 to 14 days of therapy - every four hours, two drops. If it is necessary to continue treatment for more than two weeks, the dosage regimen should be selected by the attending physician.
If the patient has a disease of the anterior segment of the eyeball, the agent should be instilled according to this scheme: one or two drops into the inflamed eye (or both) four times a day.
In case of serious infections in the first two days, the dosage regimen may include the introduction of the drug every two hours, one or two drops during wakefulness.
The duration of treatment with the drug according to the indicated indications should not be more than three weeks.
The dosage regimen for treating children over one year old is the same as for adult patients.
After using the product to reduce the likelihood of developing unwanted systemic reactions, it is advisable to lightly press a finger on the area of ​​the inner corner of the eye projection of the lacrimal sacs for one to two minutes after the procedure.
Drops for eyes are an aqueous solution for topical use in the ophthalmic field. The drug is an antimicrobial drug from the number of fluoroquinolones, it acts bactericidal against most gram-positive and gram-negative bacteria, is used to get rid of bacterial pathologies of the organs of vision (keratitis, conjunctivitis), including those provoked by microorganisms that are resistant to other groups of antibiotics.
Ciprolet eye drops are used to treat bacterial inflammation of the organs of vision and their appendages caused by bacteria sensitive to the drug:
- subacute and acute conjunctivitis;
- bacterial corneal ulcers;
- keratoconjunctivitis and bacterial keratitis;
- chronic meibomites;
- chronic dacryocystitis;
- keratoblepharitis and blepharitis.
The drug is prescribed for the prevention of bacterial complications after surgery in eye surgery, as well as after an injury. Ciprolet eye drops are used only as prescribed by a specialist, the duration of treatment and the dosage regimen are determined by the doctor. When treating an inflammatory process of moderate or mild severity, 1-2 drops are dropped every four hours (up to 6 times a day), reducing the multiplicity as the symptoms disappear. In severe inflammation of the eyes of an acute nature, you can use every hour, reducing the frequency of instillation in the future.
For the treatment of bacterial-type corneal ulcers, in the first six hours, they drop a drop of water every 15 minutes, then drop by drop every half an hour, on the second day they drop it every hour, then every four hours (up to six times a day).
In surgery, for the prevention of infectious complications, a medicine is instilled into each eye 1-2 drops once immediately before surgery, every 4-6 hours, 1-2 drops during the first day after it.
The instruction for drops "Ciprofloxacin-Akos" also does not contain information about patient reviews.
Reviews
"Ciprofloxacin-Akos" is an affordable tool for the treatment of pathologies of the organs of vision, which can be purchased at any pharmacy.
Some patients note that it is not very convenient to use eye drops, since the bottle is made of thick plastic, and at first there were problems with their dosage. The tube is very hard, so you need to make some efforts to carry out the procedure.
The advantages of the drug include:
- vast spectrum of its action;
- elimination of redness of the eyes and pain, reduction of the size of the neoplasm;
- availability in many pharmacies;
- efficacy in the treatment of barley;
- affordable cost;
- lack of side effects (individually).
The disadvantages are also noted:
- is an antibiotic;
- eliminates the symptoms of halazion, but the disease does not cure;
- slight burning sensation;
- an antibiotic is not very effective in the treatment of chronic conjunctivitis.
We reviewed the instructions for eye drops Ciprofloxacin-Akos.