"Sorbifer Durules" is a combination medicine containing ascorbic acid and iron. The medicine belongs to the group of antianemic medicines, it is used to eliminate the lack of iron in the body.
Reviews about "Sorbifer Durules" are abundant.
The drug is produced by the manufacturer in tablet form, packaged in packages of 30, 50 pieces.
Composition, description of the medication
Sorbifer Durules tablets are round in shape, convex on both sides, covered with a light yellow shade, their fracture has a gray color and a specific aroma. One of the sides of the tablet is engraved in the form of the letter Z. The main active substances in the composition of the drug are ascorbic acid, iron sulfate.
Auxiliary ingredients in Sorbifer Durules are represented by carbopol 934, povidone K25, E572, and polyethylene powder. The shell is made using hard paraffin, E172, propylene glycol 6000, hypromellose, titanium white.
Pharmacological group
Iron is necessary for the body to produce hemoglobin, and a number of oxidation processes in the tissues occur in its presence.
Thanks to the use of special technology, iron ions are released from the tablet gradually, and the absorption of the active substance in this case increases by about 30% compared with conventional iron-containing preparations. The matrix of plastic is not subjected to the destructive effect of gastric juice, due to which the active components are released from it exclusively when it enters the intestines.
Ascorbic acid is able to improve the absorption of iron. About 90% of the total dose of iron binds to plasma proteins. The active component is deposited in the liver cells and the system of phagocytic macrophages in the form of ferritin and hemosiderin. A small number of them are deposited in muscle tissue in the form of myoglobin. Half elimination takes about 6 hours.
Indications for use
According to the instructions to “Sorbifer Durules”, for adult patients, the drug is indicated for use in the treatment of iron deficiency anemia and restore normal levels of iron with a deficiency in the body. Also, the medication can be used as a prophylactic to prevent the development of these conditions in blood donors.
For children from 12 years old, “Sorbifer Durules” can be prescribed according to the same indications.
The drug can be used as a prophylactic for pregnant women and women in the lactation period. The use of the drug can prevent the occurrence of iron deficiency and iron deficiency anemia.
Contraindications
As the instructions to “Sorbifer Durules” indicate, it is forbidden to prescribe medication to patients who have the following pathological and physiological conditions:
- Individual susceptibility to the components that make up the drug.
- Increased iron concentration in the body, impaired absorption of iron. Such conditions accompany hemolytic, lead, bronze, sideroblastic anemia, hemosiderosis.
- Obstructive changes in the digestive tract, including narrowing of the esophageal lumen.
It is important to exercise caution when using tablets by patients suffering from peptic ulcer of the duodenum, stomach, inflammatory processes in the intestines, Crohn's disease, enteritis, diverticulitis, ulcerative colitis.
Use of medication
The tablets are intended for oral use. They should be washed down with liquid in a minimum amount of 100 ml.
For adult patients, the medicine must be taken once or twice a day, 1 tablet. If there is a need, then for patients with iron deficiency anemia, the daily dosage may be doubled. The total number of tablets should be divided into two uses. On average, a therapeutic course takes about 4 months until the body is replenished with iron.
Children from 12 years old are shown to use the drug in adult dosages. Reception should be carried out until the hemoglobin level returns to normal. After this, the course can be continued in order to replenish the iron depot, which takes an average of 2 months.
For pregnant women, it is recommended to take 1 tablet once a day for prophylactic purposes. For therapeutic purposes, a twice-daily intake of 1 tablet is prescribed.
Negative impact
According to reviews of Sorbifer Durules, negative consequences may develop against the background of its use, including:
- Constipation, loose stools, abdominal pains, vomiting, nausea.
- Peptic ulcer of the esophagus, its narrowing.
- Dizziness, headache.
- Allergic reactions resulting in skin rash and itching.
- Hyperthermia of the skin.
- Weakness.
In case of side effects of Sorbifer Durules, the patient is advised to consult a doctor.
Interaction with other medicines
With parallel use, the adsorption level of Methyldopa, Levodopa, Clodronate, Enoxacin, Grepafloxacin, Levofloxacin, Penicillamine, tetracycline derivatives, thyroid hormones decreases.
Concurrent use with antacid preparations based on aluminum hydroxide and magnesium carbonate leads to a decrease in iron absorption.
It is necessary to observe the interval between the use of these medicines for about 2 hours. The exception is tetracyclines, they should be taken with a difference of 3 hours.
It is not recommended to take the medicine together with Ofloxacin, Norfloxacin, Ciprofloxacin, Doxycycline.
Analogs of Sorbifer Durules will be presented below.
Overdose
When an overdose occurs, the patient develops the following symptoms:
- Acidosis.
- Paresthesia.
- Hyperthermia.
- Pallor of the skin.
- Heartbeat
- Weak pulse.
- The fall of blood pressure.
- Weakness.
- Fast fatiguability.
- A loose stool in which there is blood, vomiting.
- Cold, sticky sweat.
- Abdominal pains.
Acute iron intoxication causes:
- Symptoms of peripheral circulatory collapse.
- Decreased blood sugar levels.
- Impaired renal function, liver.
- Cramps.
- Hyperthermia.
- To.
If an overdose occurs, the patient should rinse the stomach immediately and seek help from a medical facility. You should also drink milk and a raw egg, which will bind iron ions in the digestive tract. In addition, the administration of "Deferoxamine" and the symptomatic treatment are prescribed.
Analogs of Sorbifer Durules
If necessary, the medication can be replaced with one of the analogues. The most popular are: Ferrum Lek, Maltofer, Fenyuls, Ferrogradumet.
It is important to remember that any replacement of the drug should be agreed with the doctor.
Reviews on "Sorbifer Durules"
Often there are positive reviews about the drug left by pregnant women. They note its effectiveness, ease of use, ability to quickly restore hemoglobin levels. When following the recommendations for use, the drug rarely provokes negative reactions. A positive characteristic of the drug is its availability and affordable cost.
However, despite the large number of positive reviews about Sorbifer Durules, the drug should not be used alone, but only after consulting a specialist.