Permanent itching and unpleasant odor of the legs may appear due to damage to the nail plate by the fungus. Such a disease can be easily obtained by visiting moist, warm places, for example, saunas, baths, shoe stores and pedicure salons. In pharmacies, a huge assortment of various remedies for this ailment is presented, including Mikospor, which occupies a leading position. As you can conclude from numerous reviews, this tool quickly copes with fungus limbs.
Instructions for “Mikospor” will be presented in this article.
Description
The tool can cure fungal diseases caused by yeast and mold fungi, dermatophytes, it copes with such diseases:
- superficial skin candidiasis;
- pityriasis versicolor;
- mycosis of limbs;
- erythrism;
- interdigital dermatophytosis.
"Mikospor" is a drug that has a wide range of actions. It destroys the cell membrane of a harmful fungus that has fallen into the structure of the nail.
Structure
As indicated by the instruction, "Mikospor" contains active components that affect the disease in a comprehensive manner.
Bifonazole has antimycotic and fungicidal effects. This substance begins to affect the body when its concentration reaches 5 μg / ml, the duration of exposure is 6 hours. It actively affects many yeast and mold fungi, as well as gram-positive cocci, but cannot destroy enterococci.
Urea in this drug increases its antimycotic effect, acts as a conductor of the first substance, softens the area of the affected nail.
The drug can easily penetrate the nail plate, which was affected by the fungus, and when applied to a healthy area of the skin, it will not affect it at all. As a result of studies, it was found that the absorption of the drug increases when applied to the inflamed parts of the surfaces.
Pharmacokinetics
According to the instructions, "Mikospor" penetrates deep into the damaged layers of the skin. 6 hours after its use, in different layers of the skin, the concentration reaches 1000 μg / cm3 in the upper layers of the epidermis (its stratum corneum) and in the papillary layer up to 5 μg / cm3. Therefore, all produced concentrations are located within the zone of antifungal activity. When applied to unaffected skin, a small fraction of bifonazole is absorbed (0.6-0.8% of the dose of the drug); the degree of concentration of the substance in the blood plasma as a result is always below the limits of detection.
Insignificant absorption is detected only after using the solution on the affected skin. Thus, due to the fact that a very low concentration is formed in blood plasma with local use (usually not higher than 5 ng / ml), no systemic effects are observed. The duration of stay in the skin (which is determined by the protective actions against fungal infections using the example of guinea pigs) is 36-48 hours. Bifonazole crosses the placental barrier in rats.
What else does the instructions for use with Mikospor tell us?
Indications
The tool is effective in the following cases:
- fungal infection of the skin caused by yeast-like, dermatophytes, mold fungi, including Malassezia furfur and Corynebacterium minutissimum:
- superficial candidiasis of the skin;
- foot mycoses (interdigital dermatophytosis and dermotophytosis of the skin of the feet);
- dermatophytosis of smooth surfaces of the body;
- onychomycosis (nail fungus);
- pityriasis versicolor;
- mycosis of the hands (interdigital dermatophytosis and dermatophytosis of the skin of the hands);
- inguinal dermatophytosis ;
- erythrasma.
This is confirmed by the instruction to Mikospor.
Release Forms
Can be found on sale:
- cream for external use 1%;
- solution for external use 1% (sometimes called a spray, which is wrong);
- ointment for external use (set).
The instruction for Mikospor is very detailed.
Instructions for use
Ointment is applied externally. In the absence of other purposes, the ointment must be applied to the affected nail once during the day in sufficient quantity to cover the entire area of the nail with a thick layer. After, a patch is glued on the treated nail, a dressing is applied over it and left for a day, after that the dressing needs to be changed. After the patch has been removed, the treated surface must be immersed in warm water for ten minutes, and then carefully remove the steamed part of the infected nail with a scraper. After this treatment, the nails should be well dried, and then again apply the ointment and glue with a plaster.
According to the instructions for use with the Mikospor kit, it is not necessary to cover with ointment those areas of the skin that are adjacent to the nail. If there are signs of irritation, then before sticking the patch, you can treat the skin around the nail with a paste containing zinc. Change the bandage every day. Such treatment should be continued until the steamed plate affected by the fungus ceases to move away with the scraper and the nail becomes smooth. It usually takes from one to two weeks, it all depends on the stage of a common infection and the thickness of the nail.
It also describes the instructions for the ointment "Mikospor".
The tool only affects the affected nail plate and does not affect healthy areas. After the affected nail plate has been removed, the attending physician will need to check whether the onycholysis is completed, and if necessary, the doctor will completely clean the nail bed and prescribe the final antifungal treatment. The final antifungal treatment of the nail bed must be carried out with the drug for external use once a day for four weeks. Next, consider the instructions for the solution "Mikospor".
Solution
It is applied externally, this solution should be applied not in a thick layer to the infected areas of the skin once during the day, mainly at night, and gently rub. To achieve a positive result, treatment should be continuous. The duration of therapy usually takes:
- with mycosis of the hands (interdigital dermatophytosis and dermatophytosis of the skin of the hands), body skin (dermatophytosis of smooth skin) and skin folds (inguinal dermatophytosis) - two or three weeks;
- with erythrasma and pityriasis versicolor - two weeks;
- with foot mycosis (interdigital dermatophytosis and dermatophytosis of the skin of the feet) - three weeks;
- with superficial skin candidiasis - from two to four weeks.
In order to treat a surface approximately equal to the palm of your hand, a few drops of this solution (about three drops) will suffice.
Cream
Use externally, apply the cream in a thin layer on infected areas of the skin once a day, preferably at night, rub gently. In order to achieve a good result, it is impossible to interrupt treatment. The duration of treatment is the same as in the case of the solution.
Side effects
Against the background of admission, may develop:
- allergic dermatitis;
- itching
- contact dermatitis;
- erythema;
- hives;
- pain at the site of application;
- blisters;
- dry skin
- peripheral edema (in the field of application);
- burning sensation;
- skin irritation.
Contraindications
High sensitivity to the substance bifonazole or to any other component of the drug.
Use with caution:
- during pregnancy and lactation;
- in childhood.
special instructions
It is necessary to use this drug with caution to patients who have high sensitivity to other drugs with the antifungal effect of their group of imidazole derivatives (Clotrimazole, Miconazole, Econazole). If there is an increased sensitivity to cetostearyl alcohol, medicinal types of bifonazole should be used that do not contain it. For example, use a solution instead of a cream. Avoid contact with eyes.
Reviews
The attending physicians actively advise this drug for the treatment of mycotic lesions of the skin. Reviews about "Mikospor" for the fight against fungus are relatively positive, basically everyone prefers to use a kit, which additionally includes a scraper and a patch.
We reviewed the "Mikospor" tool instructions and reviews.