In the article, we consider the instructions, reviews and analogues to Ginoflora E.
This drug is a local effect, which is designed to normalize the balance of microflora in the vagina in women.
Composition and form of release of the drug
According to the instructions, “Ginoflor E” is available in the form of tablets for vaginal use, which are packaged in special blisters of 6 pieces each. Blisters are packed in cardboard packs of one or two pieces. One vaginal tablet of the drug contains 50 mg of the main active ingredient, which is represented by the lyophisiate of acidophilic lactobacilli, as well as estriol and lactose.
Pharmacological properties
Ginoflor E medicine is intended for vaginal use. Two active substances that are included in the content of this drug, lactobacillus Lactobacillus acidophilus and estriol, are involved in the normalization of the physiological mechanisms of maintaining the correct processes of biocinosis in the vagina.
Lactobacillus acidophilus are one of the dominant bacteria that live in the vagina of healthy women and have antagonistic activity against pathogenic and conditionally pathogenic infectious bacteria.
This confirms the instructions for use for the Ginoflor E product.
Estriol is an estrogen that has a short-term protective trophic effect on the vaginal epithelium and does not affect the general condition of the body, since it is not absorbed into the blood. The mature proliferating epithelium in the vagina accumulates glycogen, which is necessary for the functioning and life of lactobacilli that produce lactic acid and maintain an acidic environment in the vagina (pH 3.9-4.4), which creates rather unfavorable conditions for the development and colonization of various pathogenic microorganisms . In addition to lactic acid, this variety of bacteria is able to produce bacteriocins and hydrogen peroxide, which also inhibit the reproduction of pathogenic microorganisms.
When is it effective?
A change in the balance of the physiological vaginal flora occurs as a result of numerous factors: systemic or local use of antibacterial drugs, including during the spread of vaginal infections or after them, various systemic diseases, with insufficient personal hygiene, etc. In these cases, the main number lactobacilli can significantly decrease.
The intravaginal use of the drug “Ginoflor E” improves the condition of the vaginal epithelium and restores the microflora balance in it. Lactose, which is also included in these vaginal tablets as an excipient, lactobacilli can be fermented into lactic acid.
Use during menopause
The internal vaginal epithelium begins to gradually thin out and, if some hormonal disorders occur, it can be damaged, and therefore the drug Ginoflor E can be used during menopause, significantly reducing its local manifestations in the form of itching, dryness of the vagina, burning sensation, pain during intercourse , normalizing the state of the epithelium of the urethra and vagina, reducing the frequency of inflammatory and dystrophic pathologies.
According to research results, Lactobacillus acidophilus, within a few hours after administration of the tablet, helps to reduce the pH, bringing its level to normal, and estriol, with a duration of therapy from 6 to 12 days, provides a trophic proliferative effect on the vaginal epithelium.
What else does the application instruction tell us about the Ginoflor E preparation?
The main active substance of this medication helps to restore and normalize microflora in the vagina and inhibit the growth and reproduction of all kinds of pathogens and yeast-like fungi.
Estriol is a kind of synthetic compound, which in its therapeutic effect is similar to some hormones produced in the ovaries in women. Estriol has a therapeutic effect exclusively on the mucous membrane in the genital tract and does not violate the basic functions of the endometrium. The drug "Gynoflor E" significantly increases the protective properties of the epithelial vaginal layer and stimulates the reproduction and growth of lactobacilli.
With the introduction of tablets intravaginally, a gradual release of the active substances occurs. The drug acts locally, without falling into the general bloodstream.
Indications for use
As the instruction indicates, “Gynoflor E” in the form of vaginal tablets is prescribed to women for the prevention and treatment of the following pathological conditions:
- With menopause in order to restore normal balance in the microflora of the vagina.
- Atrophic vaginitis.
- Prolonged use of antibacterial drugs, which often leads to disturbances in the normal vaginal environment.
- Recurrent candidiasis (thrush).
- Inflammatory processes affecting the mucous membrane in the vagina, not complicated by certain infections.
- Dysbacteriosis, which is accompanied by abundant secretions that have an unpleasant odor.
Contraindications to the use of the medication
In accordance with the instructions for Ginoflora E, before starting therapy it is extremely important to consider some contraindications, therefore, a gynecologist's consultation is necessary here. The list of main restrictions for using this medication includes:
- Individual intolerance to medicinal substances that are contained in vaginal tablets.
- Age less than 18 years.
- Bleeding from the genital tract of an unexplained nature.
- Malignant tumors in the vagina and cervix.
- Endometriosis
- Cancerous diseases of the mammary glands.
This is described in the instructions for use with the Ginoflor E tablets.
Dosage and administration
Vaginal tablets are exclusively for vaginal use.
According to the instructions for using these vaginal tablets, they must be thoroughly moistened in running water, and then deeply inserted into the vagina. A day you need to enter the drug only 1 time per day before bedtime.
During menstruation, the use of the drug should be suspended, and two days after the end of the bleeding, the therapy should be started again. The duration of the course of therapy is determined by the doctor depending on certain characteristics of the body and indications. This information can be found in the instructions for Ginoflora E.
After the patient has undergone chemotherapy or a long-term course of antibiotic therapy, vaginal tablets are prescribed 2 tablets of the drug once a day before bedtime - 7 days, after which they switch to the usual dosage - 1 tablet per day.
The duration of therapy is usually two weeks, and if necessary, it can be repeated after a certain period of time.
To prevent vaginal dysbiosis against the background of a general decrease in immune defense in the body, it is sufficient to use this medication 1 tablet once or twice a week for one month.
This is indicated by instruction. Reviews about Ginoflora E are mostly positive.
Use during pregnancy and lactation
In the first months of pregnancy, the drug should be used with extreme caution. In the second and third trimesters, such a medication is prescribed in the required dosage strictly according to the indications. Studies of the drug did not reveal embryotoxic or other negative effects of its substances on fetal development and pregnancy.
The use of this medication during breastfeeding is also carried out according to the indications and appointment of a specialist. The active substances of the drug “Ginoflor E” are not able to penetrate into breast milk, however, before using it, you should study the instructions.
Adverse reactions
According to the instructions for use and reviews for Ginoflor E suppositories, in most cases, the drug in question is well tolerated by patients. With increased sensitivity to its substances, some local reactions may occur, which can be expressed in the following:
- Discomfort in the vagina after the administration of the drug.
- Itching or burning.
- Redness of the mucous membranes of the genital tract.
Such symptoms, as a rule, manifest themselves very slightly and do not require discontinuation of the drug.
Overdose and drug interactions
There have been no cases of an overdose of this drug in medical practice. Nevertheless, it is not recommended to exceed the dosages indicated in the instructions.
With concomitant antibacterial therapy or treatment with bacteriostatic drugs using these vaginal tablets, a slight decrease in the effectiveness of Ginoflora E is observed.
In addition, it should not be used simultaneously with other topical medicines, since this can also provoke a weakening of the therapeutic effects of the former.
Vaginal suppositories "Ginoflor E" according to the instructions should be used carefully.
special instructions
During the use of the drug should refrain from sexual intercourse. This medicine may adversely affect the integrity of latex barrier contraceptives, which is necessary to warn patients who do not plan a pregnancy.
This is confirmed by the instruction.
Analogues of Gynoflora E
The following medicines are similar in therapeutic effect with these vaginal tablets:
- "Vagilak."
- Gentaxan.
- "Terzhinan."
- Ginolact.
Reviews
This drug is very popular among women of all ages. Judging by the reviews of most patients, they are very pleased with this medication, because they believe that it helped them cope with many problems in the female genital area. The main positive quality of this drug, in their opinion, is its safety and the absence of toxic effects on the body, which is very important for such categories of women as pregnant women or those who suffer from concomitant diseases in chronic forms, in which many medicines are contraindicated.
The reviews indicate that Ginoflor E vaginal suppositories have a positive effect on the well-being of women who have suffered from pathologies such as candidiasis or vaginal dysbiosis. As a result, the balance of microflora that lives in normal amounts in the vagina is disturbed, and unpleasant symptoms such as profuse discharge, sometimes with an unpleasant odor, itching with thrush, dry mucous membranes, pain during sexual contact, etc.
As for adverse reactions from the use of this drug, women note its good tolerance, with the exception of some cases of minor discomfort in the vagina in the form of burning and swelling. A certain category of patients also showed minor allergic reactions to the substances of the medication, but they did not cause any significant inconvenience.
Women noted that after a course of treatment with these vaginal tablets, the discomfort disappeared after the first days of their use. For many of them, therapy with this medication was prescribed again to prevent genital tract diseases and consolidate the therapeutic effect.
The main thing is to adhere to the instructions for the use of Ginoflora E.
There are negative reviews about vaginal tablets, but they are relatively few in number. At the same time, women claim that they did not notice the particular effectiveness of this medication, and the symptoms of the underlying disease, even after the full course of treatment, remained or decreased, but not significantly. In such cases, they were prescribed complex therapy, which included not only the local use of such drugs, but also the systemic administration of probiotics.
We examined the Ginoflor E candles, instructions, reviews and analogues.