How should I use Oflokain-Darnitsa ointment? Instructions for the use of local funds will be described below. You will also learn about what medicinal properties are characteristic for this drug, what it is prescribed for, and whether it has analogues.
Packaging, composition
What are the ingredients of Oflocaine (ointment)? Instructions for use indicate active ingredients such as ofloxacin and lidocaine hydrochloride.
You can buy this tool in aluminum tubes of 30 or 15 g, which are placed in paper packaging. Also, the drug in question is available in glass jars of 1000 or 500 g.
Pharmacology (main properties of drug components)
What is a remedy like Oflocaine (ointment)? The instruction for use reports that this is a combined medication that has antimicrobial, analgesic and decongestant properties. The mechanism of action of this drug, as well as its therapeutic effects, are based on the pharmacological characteristics of its active components.
Ofloxacin, which is part of the drug, is an antimicrobial substance belonging to the group of fluoroquinolones. The principle of action of this component is based on its ability to inhibit topopisomerase IV and DNA hydrase, due to which DNA replication of harmful microorganisms is inhibited.
The medication in question is highly effective against gram-negative, anaerobic, asporogenous, aerobic and spore-forming microorganisms, as well as gram-positive bacteria.
It should be noted that ofloxacin is active against hospital strains that are resistant to sulfonamides and antibiotic agents.
What role does lidocaine play in Oflocaine? Ointment, the instructions for which are presented below, thanks to this component, belong to the group of local anesthetics.
As you know, lidocaine is a derivative of acetanilide. Its mechanism of action is associated with the ability to stabilize cell membranes and block Na channels. As a result of this process, lidocaine inhibits the conduction and generation of impulses in nerve fibers.
The drug in question is equally able to block pain impulses and impulses of other modalities. Local use of lidocaine does not affect the myocardium.
Pharmacokinetics of local medication
Is an agent such as Oflokain (ointment) absorbed? The instruction reports that this drug has a hyperosmolar base, which reduces the swelling of tissues located around the wound.
When applied topically to intact skin, the active ingredients of this product are not absorbed into the systemic bloodstream. However, after applying the ointment to the damaged areas, approximately 3% ofloxacin can enter the systemic circulation. Its peak plasma concentration is reached within 4 hours. But after six hours, the active ingredient of this remedy is no longer detected in the blood.
Indications for applying ointment
For what purposes can a drug such as Oflokain (ointment) be prescribed? Instructions for use (a photo of the drug is presented in the article) claims that this medication is actively used as an antimicrobial local medicine in the following cases:
- In combustology - for the prevention of suppuration and the treatment of burn wounds.
- In surgery, for the treatment of people with infected wounds in the first phase of the wound healing process of various origins and localizations, including pressure sores, fistulas, trophic ulcers, complicated postoperative abscesses and wounds, as well as phlegmons of the jaw and facial area.
- In traumatology - for the prevention and treatment of purulent complications.
It should also be said that the said ointment is used in dermatological practice to treat patients with purulent-inflammatory diseases of the skin, which are caused by microorganisms that are sensitive to the action of the drug.
Contraindications to the use of a local drug
When can’t you use Oflokain (ointment)? The instruction for use reports such prohibitions as:
- pregnancy period;
- increased individual sensitivity to ointment substances, as well as drugs of the fluoroquinolone group;
- breast-feeding;
- the second phase of the wound healing process.
"Oflokain" (ointment): instructions for use
For children, this drug is prescribed with caution (strictly according to indications). It is used only externally. A small layer of ointment is applied to the pre-treated skin area, after which a sterile gauze dressing is immediately applied. It is also possible to apply the drug directly to the dressing.
Tampons soaked with the medication in question are actively used to fill purulent wounds and their cavities, including after surgery.
Gauze turunds with a drug are used for their introduction into the fistula passages.
The duration of the course, as well as the dosage of this medication, is determined by the attending doctor (individually).
For adults, for the treatment of purulent wounds, it is usually recommended to apply the ointment once a day. In the treatment of burns, this drug is used every day or three times a week (depending on the severity of the injuries received).
For the treatment of dermatological diseases, the medication should be used twice a day.
The amount of ointment used is determined by a specialist (depends on the area of damage and the degree of purulent exudation).
Side effects after applying a local ointment
What adverse reactions can cause Oflokain (ointment)? Instructions for use states that usually this drug is well tolerated by patients. However, in some cases, when applied to a burn surface, a person may develop a burning sensation that passes within a few minutes, and also does not require the cessation of treatment.
Similar means
Now you know what properties the local drug Oflokain (ointment) has. Instructions for use, analogues of this medication are also presented in this article.
Replace the drug in question can be such means as Lomadey, Levomak, Loksof, Levobaks, Dermoveyt and others. However, it should be noted that such drugs may have their own adverse reactions and methods of use. Therefore, they should be used instead of Oflokain ointment only after prior consultation with the treating doctor.