"Vilprafen" is a broad-based antibacterial medicine that belongs to macrolides. The active components of the drug are detrimental to most pathogenic microorganisms. The medication is prescribed for various bacterial infections.
In what forms is the drug produced?
According to the instructions for use, "Vilprafen Solutab" (1000 mg) is made in the form of tablets for oral administration, in blisters of ten pieces. Each tablet is coated with a film coating of a milky tint and has a horizontal line on one side.
The active microelement is josamycin (one thousand milligrams). Additional components are:
- magnesium salt of stearic fatty acid;
- talc;
- cellulose;
- titanium dioxide;
- ethylene glycol polymer;
- aluminum hydroxide.
Pharmacological properties
According to the instructions for use with Vilprafen (1000 milligrams), the main substance of the medication adversely affects inflammation in the body, reducing the synthesis of protein by bacteria. The current trace element has the ability to persist in the source of infection, thereby the drug has a strong antibacterial effect. The medicine is effective in relation to:
- Helicobacter pylori;
- clostridium;
- peptococcus;
- peptostreptococcus;
- chlamydia
After taking the drug inside, the main trace elements are instantly absorbed through the membrane of the digestive system into the blood. The maximum concentration of the active ingredient in the blood is observed a couple of hours after the use of the drug. The highest content of substances can be found in the patient in the sweat glands, urogenital secretions, semen, bile.
Indications for use
The drug is prescribed to individuals for the treatment of the following disorders:
- Bronchitis (inflammation that affects the mucous membrane or the entire thickness of the wall of the bronchi).
- Pneumonia (infection of the lung tissue, as a rule, inflammation occurs with the main lesion of vesicles in the lungs).
- Pharyngitis (instant or gradual pathological process of the mucosa of the posterior wall of the larynx).
- Sore throats (infectious disease in the form of severe inflammation).
- Tonsillitis (prolonged inflammation of the pharyngeal and palatine tonsils).
- Sinusitis (pathological process of the inner lining of the hollow paranasal sinuses).
- Otitis (a sharp or systematic inflammatory process in various parts of the ear).
- Inflammation of the larynx.
- Acute inflammation localized in the peri-amydalin fiber appears as a result of the spread of the inflammatory process.
- Bronchopneumonia (lung disease involving all structural elements and mandatory damage to the alveoli).
- Periodontal disease (systemic lesion of the complex of the tooth tissue).
- Gingivitis (gum disease without disturbance of the gingival joint).
- Flux (a purulent disease that affects the subgingival and subperitoneal jaw area).
- Alveolitis (diffuse inflammatory lesion of the dental socket).
- Boils (a sharp purulent pathological process of the gland of external secretion and the surrounding adipose tissue, which are caused by necrotic bacteria).
- Carbuncle (an inflammatory process near the existing hair follicles with the formation of an extensive source of necrosis in the skin).
- Acne
- Pyoderma (purulent infection of the skin, which develops as a result of the introduction of harmful carriers into it).
- Abscesses (inflammation of the tissue with the formation of a limited purulent lesion surrounded by granulation tissue).
- Erysipelas (a sharp, often repeated, infectious disease caused by streptococcus).
- Infection, a characteristic feature of which is the defeat of the skin of the lungs and intestines.
- Lymphadenitis (inflammation of the lymph nodes, often accompanied by suppuration).
- Lymphogranulomatosis (a malignant increase in the number of structural elements of lymphoid tissue, the characteristic feature of which is the occurrence of granulomas).
- Cystitis (a bladder disease, most often infectious).
- Urethritis (an inflammatory process in the urethra caused by damage to the canal wall by various bacteria and viruses).
- Pyelonephritis (inflammation of the kidneys, which occurs in acute or chronic form).
- Inflammation of the prostate gland.
- Salpingoophoritis (inflammatory process with simultaneous involvement of the ovaries and fallopian tubes).
- Inflammation of the uterus.
- An inflammatory disease of the cervix or otherwise cervicitis (inflammation of the cervix, which includes infection of the vaginal mucosa).
- Septic abortion (a complication after abortion that occurs in community-acquired conditions in people with immunodeficiency).
- Gonorrhea (an inflammatory disease that is caused by gonococcus).
- Chlamydia (an infectious disease that is transmitted with intimacy).
- Ureaplasmosis (an inflammatory disease of the genitourinary system, which is caused by the pathological activity of ureaplasmas).
Contraindications
"Vilprafen" is not recommended for patients with the following diseases and conditions:
- Individual intolerance to the trace elements that make up the drug.
- Damage to the kidneys and liver.
- Bearing a child.
- The period of breastfeeding.
- Severe allergic manifestations of drugs from the macrolide group.
Instructions for use
Adults "Vilprafen Solutab" must be taken as a whole orally, washed down with water. The drug is usually consumed after a meal or half an hour before it.
The dosage of the drug and the duration of therapy are prescribed by the doctor for each patient purely individually. This primarily depends on the disease, the course of the inflammatory process, complications, hypersensitivity to the components of the drug, age, weight.
According to the instructions for use "Vilprafen" (500 mg), the maximum dosage for adult patients and adolescents is one to two grams, which are divided into several times. At first, the doctor prescribes one tablet twice a day for adults. The duration of the course for various diseases will vary, but the medicine should be used for at least five days, a maximum of fourteen days.
In the absence of a therapeutic effect and improvements, the patient should consult a therapist to clarify the diagnosis and prescribe another medication. If the patient feels better, but the course of therapy is not yet finished, you should never cancel the medication yourself. In this situation, the inflammation will again make itself felt, but with greater strength, and the source of infection will already have immunity to josamycin, and then the doctor will have to look for a new medicine, stronger and in a larger dosage.
According to the instructions for use "Vilprafen", for children there is a special form of the drug - suspension.
Can I take medicine during pregnancy?
This antibacterial agent is not prescribed for the treatment of women in an interesting position. Active trace elements of the drug are able to easily penetrate the placenta, causing fetal pathology.
Tablets during breastfeeding are contraindicated for use. If therapy with this medicine is necessary, a woman needs to interrupt her feeding or consult a therapist to select another medication.
Side effects
When using Vilprafen (according to the instructions for use and exact adherence to dosage) it is well tolerated by patients, but in rare cases, negative reactions may occur:
- nausea;
- colic in the stomach;
- increased salivation;
- burning sensation in the chest;
- gagging;
- persistent diarrhea;
- increased activity of liver enzymes responsible for intracellular metabolism and linking carbohydrate metabolism with nitrogen compounds;
- violation of the outflow of bile;
- disruption of the gallbladder;
- anaphylaxis (immediate allergy, the condition instantly increases the sensitivity of the body).
Overdose
Currently, there is no information on cases of negative reactions in patients with the correct observance of the instructions for use of Vilprafen (1000 mg). With an increase in the standard dose, people may develop complications in the functioning of the stomach and intestines - severe vomiting, nausea, enlarged liver, and diarrhea. In some situations, kidney and liver problems may occur.
Interaction with other medicines
It is necessary to avoid prescribing Vilprafen tablets with antibacterial drugs from the penicillin or cephalosporins group, as this can lead to severe disturbances in liver function, diarrhea and dehydration. In difficult cases, a coma may occur.
With the joint use of an antibiotic with xanthines, the patient may manifest increased intoxication of the body.
With the simultaneous administration of Vilprafen to the patient with antihistamines, it is possible to develop severe disorders in the cardiovascular system, in particular cardiac arrhythmias.
With the simultaneous administration of tablets with hormonal medications, it is possible to reduce their effect, about which it is necessary to warn patients. During therapy with antibacterial agents, therapists recommend the use of condoms.
Storage and price
According to the instructions for use, "Vilprafen Solutab" (1000 mg) is dispensed in pharmacies without a prescription. For elderly people, as well as patients with severe problems in the functioning of the liver and kidneys, this medicine should be prescribed with extreme caution.
During therapy, it is necessary to periodically monitor the general state of human health and the clinical picture of the blood.
The medication must be stored out of the reach of children, at a temperature of no more than twenty-five degrees according to the instructions for use of Vilprafen. The price (1000 mg) is seven hundred rubles per pack.
"Wilprafen" analogues
The following drugs are referred to generics of the drug, which are similar in their therapeutic effect:
- Erythromycin.
- "Azithromycin".
- Sumamed.
- Clarithromycin.
- Roxybide.
- "Rovenal."
According to reviews and instructions for the use of "Vilprafen", the price corresponds to the quality of the drug. The medication has a gentle effect, so the risk of adverse reactions is zero, which is confirmed by many medical studies. The medicine reliably eliminates the focus of infection in both the body of children and adults.
Erythromycin
A drug from the macrolide group. It is produced in the following dosage forms:
- pills
- eye ointment;
- ointments for local and external use;
- lyophilisate for solution for intravenous injection.
The active substance is erythromycin. An active trace element disrupts the formation of bonds between amino acids, blocking the process of combining bacteria proteins. The use of "Erythromycin" in high dosages contributes to the manifestation of its therapeutic effect.
Erythromycin tablets must be taken orally. The maximum daily dosage for adults and adolescents over fourteen years is two grams. If necessary, the daily dosage is increased to four grams. The interval between doses should be six hours. Children from four months to eighteen years of age, depending on the weight, age and complexity of the disease, are prescribed 0.03-0.05 grams per kilogram of weight per day four times a day. The duration of treatment is fourteen days. The cost of the drug is ninety rubles.
"Azithromycin"
Tablets are taken in the treatment of various diseases that are caused by bacteria sensitive to the main substance. It exerts an effect on the ribosomes of a bacterial cell, after which the protein compound process is disrupted and the death of the microorganism occurs. Depending on the concentration, the drug can inhibit the growth and reproduction of bacterial cells or lead to the death of microorganisms. In relation to the source of infections, the drug has a wide spectrum of activity. It contributes to the suppression of streptococci and staphylococci, as well as bordetellas, moraxellas, gardnerells, and neisseries.
"Azithromycin" has a high activity against the source of genital infections. After using the tablet, the active trace element is absorbed into the bloodstream and spreads to the tissues.
"Azithromycin" tablets are taken orally after a meal or in one to two hours. They are not chewed and washed down with a sufficient amount of water. The average dosage depends on the indications:
- Infections of the upper and lower respiratory tract, as well as skin and soft tissues (with the exception of Lyme disease) - five hundred milligrams once a day for three days.
- Lyme disease - one thousand milligrams (two tablets) on the first day once, then five hundred milligrams once a day from the second to the fifth day of treatment.
- Diseases of the urogenital tract - one thousand milligrams once.
- With acne, five hundred milligrams, then a break, and from the eighth day from the start of therapy, five hundred milligrams is taken once a week for nine weeks.
The cost of the drug varies from one hundred to three hundred rubles.
Sumamed
The drug is used to treat various infectious pathologies aimed at eliminating pathogenic bacteria sensitive to this medicine. The tablets are coated with an enteric coating, have a white tint, round shape. The active active trace element of the drug is azithromycin, its content in one tablet is five hundred milligrams.
After using the drug "Sumamed" the active component of the drug is instantly and completely absorbed from the intestine into the blood. It is evenly distributed over all tissues with a slightly increased concentration in the lungs, respiratory tract, as well as in the structures of the urogenital tract. It can penetrate into the cells through the plasmalemma. The drug most accumulates in the tissues affected by the infection. The cost of the drug varies from two hundred to seven hundred rubles.