The medicine "Tevastor" is in the category of lipid-lowering drugs. The drug competitively selectively inhibits HMG-CoA reductase. The medication increases the number of LDL receptors on the surface of hepatocytes, lowers cholesterol. Hypolipidemic activity is directly proportional to the dosage. From the beginning of treatment, therapeutic efficacy is observed after a week. After 14 days, the maximum effect is observed, after a month the effect of the drug becomes constant. When eating, the absorption rate decreases. Withdrawal of the drug occurs unchanged (mainly) with feces.
The medicine "Tevastor." Instructions for use. Appointment
The medication is indicated for primary or mixed hypercholesterolemia as an addition to the diet and for other cholesterol lowering therapy or the ineffectiveness of another treatment.
The drug "Tevastor." Instructions for use. Contraindications
The drug is not recommended for liver diseases of the active phase. In particular, no agent is prescribed for any, including persistent, increase in the activity of transaminases more than three times in comparison with the upper level of the norm. The drug "Tevastor" does not recommend instructions for use in cases of severe impairment of renal activity, together with cyclosporine, and myapathy. Contraindications include lactation, gestation, age up to 18 years. Do not prescribe medication for women of reproductive age who do not use adequate methods of contraception. Caution when prescribing Tevastor (instructions for use, reviews of specialists indicate this) should be observed with patients over the age of 65, with liver pathologies, arterial hypotension, and sepsis. Dose adjustment (in rare cases) may be required in conditions after operations, injuries, metabolic, electrolyte or endocrine disorders, uncontrolled epilepsy, proteinuria.
The drug "Tevastor." Instructions for use
The initial dose is 10 mg once a day. Four weeks later, if necessary, the amount of medication can be increased to 20 mg. Increasing the dosage to 40 mg is allowed only as prescribed by a specialist in the absence of the effect of lower doses. With a tendency to develop myopathy, the initial amount of the drug is 5 mg.
The drug "Tevastor." Instructions for use. Side effects
Negative reactions are usually dose dependent. Based on therapy
neuralgia, headache, anxiety, abdominal pain, nausea, depression,
asthenic syndrome. The medicine can provoke a heartbeat, dyspepsia, pneumonia, bronchial asthma, angina pectoris. Patients may have muscle hypertonicity, myalgia, myopathy, arthritis. Negative effects include lesions in the urinary tract, arthralgia, allergic reactions, pain in the lower abdomen, angioedema.
Means "Tevastor." Instructions for use. Price
The cost of the medication is about 300 rubles.