The accelerated pace of life, regular stress and nervous strain in modern society have led to a noticeable increase in the incidence of peptic ulcer of the stomach and duodenum. The danger of pathology is that erosion is able to reach the bottom of the muscle layer, provoking perforation of the wall of the stomach or intestines. Untimely assistance and unqualified treatment can ultimately lead to death, therefore, experts say the need for timely treatment. The range of medicines for this disease is diverse, allowing the doctor to optimally choose the medicine itself or its analogues: "Sanpraz", "Nolpaza", "Omeprazole".
Digestive Aggression Factors
An important factor in the development of ulcerative erosion is the aggressive effect on the mucous membrane of the digestive system against the background of a decrease in its protective capabilities. The factors of aggression include:
- increased production of hydrochloric acid;
- infection of the mucous membrane with microorganisms;
- gastrointestinal motility disorders;
- oxygen starvation of the gastric mucosa;
- throwing the contents of the duodenum into the stomach.
Most often, these factors work against a background of stressful situations, when infected with bacteria and injured the mucous membrane during diagnostic procedures.
The action of antisecretory drugs
The number one drugs in the treatment of erosive pathologies of the stomach are recognized as drugs aimed at reducing the secretion of gastric juice: sanpraz, analogues and substitutes for this antisecretory drug .. Excessive production of hydrochloric acid disrupts the microflora of the mucous membrane, making it susceptible to bacteria.
Antisecretory inhibitor drugs in their therapeutic pathway go through several stages:
- Once in the stomach, they are transported to the small intestine;
- dissolve in the intestines, enter the bloodstream;
- inhibit blood flow into the liver, then into the stomach;
- accumulating, it is converted to tetracyclic sulfenamide;
- block the proton pump, excluding it from the process of production and transportation of hydrochloric acid;
- reduces the volume of hydrochloric acid in the stomach, minimizes its effect on the mucous membranes.
In this way, antisecretory drugs minimize the negative effect on the mucous membrane of the stomach and intestines of hydrochloric acid, and contribute to the acceleration of the healing of erosion.
A variety of inhibitory agents
The basis for inhibitors that reduce secretory function are active substances of a certain direction of action. Therefore, in the modern pharmaceutical market there are a lot of both inhibitor drugs themselves and their analogues.
- Pantoprazole-based preparations: Sanpraz and Nolpaza, Peptazol and Kontrolok.
- Means based on omeprazole: Omez, Promez, Ortanol, Omezol, Gastrozole.
- Preparations based on lansoprazole: "Lanzap", "Helikol", "Lanzoptol", "Epicurus".
- Medicines based on rabeprazole: Zolispan, Pariet, Rabelok.
The popularity of drugs based on active substances is based on the fact that they act most sparingly on the mucous membrane, minimize the risk of side effects.
Preparations and analogues
Doctors consider analogues of any drug to medicines with a similar active active substance. Inhibitor preparations have many analogues, the most popular are sanpraz analogues.
A drug | Active active substance | Indications | Contraindications |
Sanpraz | Pantoprazole | Stressogenic etymology ulcer Gastric and duodenal ulcer Erosive gastritis Reflux - Esophagitis | Dysepsia of neurotic origin Gastrointestinal cancer Childhood Hypersensitivity to pantoprazole |
"Nolpaza" | Pantoprazole | Gastric and duodenal ulcer Erosive and ulcerative lesions while taking steroid drugs Reflux esophagitis Erosive gastritis | Dyspepsia of neurotic etiology Under 18 years old Hypersensitivity to pantoprazole |
Omez | Omeprazole | Gastric and duodenal ulcer Reflux esophagitis Erosive and ulcerative lesions while taking steroid drugs Stress ulcers | Child age Pregnancy Lactation Hypersensitivity to the drug |
The rules of treatment "Sanprazom"
Depending on the pathogenesis of the disease, the severity of symptoms, specialists prescribe a specific dosage form of the drug "Sanpraz". Instructions for use (analogues are also selected by the doctor) stipulates the universal administration of the drug:
- For the treatment of gastric ulcers, doctors prescribe a tablet form of Sanpraz 40 mg. Rules of administration: 1-2 tablets (depending on the severity of symptoms) in the morning before meals, swallow whole, washed down with plenty of liquid. After the onset of the remission period, the drug should be drunk in a prophylactic dose - ½ tablets per day for two months.
- A duodenal ulcer and erosive gastritis are treated in a similar way. The therapeutic course - no more than two weeks.
- Erosive pathologies caused by taking steroid drugs are treated with Sanpraz. The tablets are taken orally on an empty stomach, washed down with a sufficient amount of liquid. The course of administration: the first two weeks, 2 tablets, the next month and a half - ½ tablets.
- Reflux esophagitis is treated according to a similar scheme: 40-80 mg of the drug in bitches for two weeks.
Side effect of Sunprase
The use of sanprase, like any other medicine, has a risk of side effects during treatment. Most often, they occur against the background of an uncontrolled intake of the drug or an incorrectly adjusted dosage.
- Pathologies of the nervous system are manifested in depressive states, causeless headaches, hallucinations and problems with orientation.
- Side effects from the hematopoietic system are manifested in a violation of the formula of platelets and leukocytes.
- The gastrointestinal tract can respond to the intake of sanprase by pain spasm, intestinal dysfunctions, an increase in the level of liver enzymes and bilirubin in the blood.
- Local manifestations are diagnosed with symptoms of urticaria, skin itching, and laryngeal edema.
- Violation of body thermoregulation , manifested in an increase in body temperature.
Treatment with analogues of Sanpraza
Sometimes patients do not particularly trust in imported drugs, considering them an unreliable tool that provokes side effects. "Sapraz" refers to imported drugs, so doctors use the full analogs of "Sanpraz", which include "Nolpaza", "Ultra", "Peptazol".
The advantage of nolpase is that this medicine is produced by domestic pharmaceutical companies; in comparison with many other medicines, it has a mild and gentle effect. The following benefits of this medicine are considered:
- low cost;
- gentle and soft action;
- good tolerance;
- minimum side effects.
Therapy with other inhibitors
A omez is considered to be a well-known known inhibitor drug for the treatment of ulcerative erosive pathologies of the stomach and intestines. Sometimes the doctor faces a choice: “Sanpraz” or “Omez”, despite the fact that the active substance of both drugs is identical.
The preparations "Sanpraz" and "Omez" have much in common:
- Both drugs have an antiulcer effect.
- The same principle of action ..
- The same amount of active substance.
- The coincidence of side effects.
This allows patients to conclude that these drugs are completely identical, qualifying Omez as full Sanpraz analogues.
Different similar drugs
Despite the fact that Omez and Sanpraz are considered analogues, there is a significant difference between these drugs, which should be considered when choosing a medicine.
The differences include:
- different, but identical active substance;
- a more delicate effect of sanprase, minimizing the risk of side effects;
- a shorter period of taking sanpraz to achieve the desired therapeutic effect;
- higher degree of safety of sanitary protection and a wider spectrum of action compared with omez;
- the frequency of taking sanprase is less than omeza ..
Omez has established itself as a relatively simple drug that is used primarily in the treatment of ulcers or gastritis. Modern "Sanpraz" has a wider range of effects on the pathological conditions of the gastrointestinal tract, therefore, with complicated pathologies, "Sanpraz" or "Nolpaza" are recommended for treatment.
Patient Reviews
Most patients taking antisecretory drugs to eliminate the symptoms of peptic ulcer of the stomach and intestines respond positively to the drug "Sanpraz". Reviews (analogues are also considered for comparison) note the mild effect of the drug "Sanpraz".
According to reviews, Sanpraz and Nolpaza:
- differ in the long prolonged action;
- acts effectively even against the background of errors in the diet;
- relieves heartburn and nausea.
Negative reviews are those that, against the background of treatment with these drugs, the patient's mental state worsens. Some note their psychological state as uncomfortable, continuing throughout the period of taking "Sanpraza". Those who continued treatment, despite the discomfort, pay attention to the fact that depression accompanied their entire therapeutic course.
Recommendations for choosing a drug
Absolute and complete analogues are considered drugs "Nolpaza" and "Sanpraz". Doctors, as a rule, prescribe to patients any of these drugs, based on the individual characteristics of the patient's body.
“Omez” has long been considered equally effective. Those patients who are accustomed to this particular drug are not recommended to change the treatment regimen, despite the fact that omez acts more aggressively on the mucous membrane of the gastrointestinal tract.
Experts draw attention to the fact that the choice of a drug or its analogue should be entrusted to a qualified specialist, self-medication is dangerous and can lead to a complicated course of the disease.