In the article, we consider the instructions for use and reviews for the drug "Orvirem".
When the cold season comes, namely in the autumn-winter period, influenza viruses spread especially quickly among those who are susceptible to them. First of all, children are at risk of infection. To prevent infection, as well as to stop the harmful microorganism that has already entered the body, antiviral drugs are prescribed. Of great popularity among antiviral agents has "Orvire". Below we consider the drug in terms of its properties, as well as possible contraindications and adverse reactions.
Structure
Orvirem is produced in a single form - syrup. The drug is packaged in 100 ml bottles. The liquid itself is viscous and thick, has a pink or light red hue. The syrup is sweet, tasting like strawberries, but with a small bitterness.
This is indicated in the instructions for use with Orvirem. Tablets for sale can not be found.
Remantadine hydrochloride acts as the active component of the drug . The content of the active substance is 2 mg. per milliliter of syrup. A teaspoon thus contains 10 mg of remantadine (based on 5 ml of syrup).
Excipients are also present in the preparation and include sugar, water, food coloring and sodium alginate. All these components allow you to make the syrup thick and sweet so that it is convenient to give it to children. Ethyl alcohol is absent in the preparation.
The properties
According to the instructions for use, Orvirem has a powerful antiviral effect. Remantadine is particularly active against influenza virus strain A2. A similar property of the drug prevents the transfer of genetic material from virus particles to affected cells. In addition, remantadine prevents viral cells from multiplying. All this prevents the spread of the virus and reduces the number of harmful cells.
According to the instructions for use with Orvire syrup, when it is taken at the very beginning of the disease, immediately after the onset of flu symptoms or a few days before they occur, the likelihood of developing a pathology is significantly reduced. If the flu has had time to manifest itself, then while taking the syrup, the symptoms will be less pronounced, and the course of the disease will not be severe. It is considered optimal to take the drug in the first 6-7 hours after the onset of infection. However, with a later admission, up to 18 hours from the onset of the disease, patients feel relief in their condition. Instructions for use with Orvirem are very detailed.
Indications
It is most commonly prescribed for the treatment of influenza. The drug is taken not only as a therapeutic agent, but also as a prophylaxis. Sometimes it is prescribed for children who were in contact with a member of the family who had the flu or who were in the children's team at the time of infection.
Contraindications
Syrup is not prescribed for children until they are one year old. The drug is contraindicated in newborns. Other restrictions for taking Orvireme may include the following conditions:
- An acute liver disease.
- A history of kidney disease.
- Thyrotoxicosis.
- Hypersensitivity to the components that make up the drug.
In the presence of epilepsy in a child, the drug is taken under the supervision of the attending physician, since the likelihood of a seizure during treatment with Orvire increases. It is also important to consider that the composition of the drug includes sugar. Therefore, diabetics should take the syrup in low dosages and with regular monitoring of glycemic indicators.
What else can you learn from the instructions for use of Orvirem baby syrup?
Adverse reactions
The development of adverse reactions to medication is not excluded. So, syrup can provoke an upset digestive system, accompanied by symptoms such as flatulence, pain in the stomach, loss of appetite, nausea, etc.
If the child is prone to allergies, then his body can respond to taking the syrup with urticaria and other types of rash. In addition, such reactions from the nervous system as sleep disturbance, weakness, pain in the head, etc. are possible. Specific treatment for the occurrence of adverse reactions is not required. It is necessary to cancel the drug and carry out symptomatic treatment, which involves taking antihistamines.
The instructions for use "Orvireme" does not mention cases of exceeding the dosage or any consequences of such a violation of the dosing schedule.
Combination with other drugs
It is not recommended to be taken simultaneously with antiepileptic drugs, since under the influence of remantadine their effectiveness decreases.
In combination with binders, envelopes or adsorbents, the absorption of remantadine is significantly reduced. The same applies to antacids.
Substances that oxidize urine, such as sodium bicarbonate, increase the severity of the action of Orvirem, which is caused by an obstacle to its excretion by the kidneys.
The concentration of remantadine in the blood becomes lower while taking syrup with acetylsalicylic acid and paracetamol.
Instructions for use "Orvireme"
Before collecting the required amount of syrup, you must shake the bottle well to achieve uniformity of the drug. As a rule, the dosage is prescribed in teaspoons at the rate of 5 ml. Syrup is taken after meals, and if it is necessary to drink the drug, the child is given purified water.
Instructions for use "Orvireme" for children should be strictly observed.
The regimen of the drug depends on the indications and severity of the child's condition. As a rule, in childhood, the duration of treatment is four days in the following dosages:
- The first day - two tablespoons three times a day, if we are talking about a child under three years old, from 3-7 years a single dosage is 15 ml., For children from 7 to 14 years old the amount of syrup at one time is 20 ml.
- The second day - the amount of admission is reduced to two times a day. The dosage remains the same as on the first day.
- Taking the drug on the third day of treatment remains the same as on the second.
- The fourth day - the intake of syrup is reduced to once a day.
For preventive purposes, the drug is taken for 10-15 days once a day. The dosage is similar to that indicated for treatment.
This is confirmed by the instructions for use for children's "Orvirem".
Analogs
There are a number of antiviral drugs that can become a substitute for Orvir:
- "Remantadine." In composition, it is a complete analogue of Orvirem, but they are produced in the form of tablets, which excludes the use of the drug by children under seven years of age.
- Amiksin. The composition of the tablets includes tilorone, which is active against herpes, influenza, hepatitis and other viral pathogens. Assigned to children from the age of seven. Often used as a prophylactic to exclude influenza and SARS during the fall and winter.
- Kagocel. The drug has a stimulating effect on the production of interferon, which helps to strengthen the immune system. It is prescribed for the treatment of influenza, herpes and other viral diseases of an infectious nature. "Kagocel" is appointed from three years. It is also used for prevention.
- Arbidol. It has an antiviral and immunostimulating effect. It is prescribed for the treatment of rotavirus infection, SARS and influenza. Available in capsule form as well as suspension powder. Children are given it in the minimum dosage, starting from three years.
- Ergoferon. It is an antiviral drug in the form of lozenges. It has anti-inflammatory properties. Children can be given tablets dissolved in water, starting from six months.
- Ingavirin. Antiviral and anti-inflammatory agent. It can be prescribed from 13 years. Active against influenza, adenovirus, etc.
- "Tsitovir-3." It is produced in the form of a syrup that can be given to children from the age of one.
Replacing one drug with another requires a mandatory consultation with a doctor.
Opinions
For quite a long time, drugs based on remantadine as an active ingredient were not prescribed for children, as specialists did not have enough confidence in the safety of such drugs. However, in the production of Orvirem, a new formula of remantadine is used, which allows to improve the properties of the active component, while significantly reducing the likelihood of adverse reactions.
Reviews about "Orvir" confirm the opinion of experts about the safety of the drug. Instructions for use are not satisfactory, since the regimen for taking the drug is clearly and in detail. Determining the required dosage is very simple, as it is measured in teaspoons.
Parents especially note the performance of the Orvire. In this case, the drug is very well tolerated by children of any age. In combination with immunomodulators like Interferon, Viferon, Genferon and Anaferon, the action of the syrup increases significantly. Most often, Orvirem is prescribed precisely in combination with the listed drugs.
In the reviews you can find information about the effectiveness of "Orvireme" at high temperature, especially if you use the prescribed dosage regimen. As a prophylactic, syrup is also the best suited. In the vast majority of cases, when taking "Orvire" the person’s condition improved. The progression of the disease stops. Only a few hours after taking the severity of symptoms such as a runny nose and temperature decreases.
Negative reviews
However, there are negative reviews about taking "Orvireme". Some parents express the idea of the uselessness and inappropriateness of taking antiviral drugs. They emphasize that a similar effect can be achieved in more gentle and natural ways. However, there are fewer such people than those who enthusiastically respond about the medication.
We reviewed the instructions for use in syrup for children "Orvirem".